ID   U7Q783_SPOS1            Unreviewed;       878 AA.
AC   U7Q783;
DT   22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT   22-JAN-2014, sequence version 1.
DT   27-MAR-2024, entry version 31.
DE   RecName: Full=Spindle pole body component {ECO:0000256|RuleBase:RU363050};
GN   ORFNames=HMPREF1624_00886 {ECO:0000313|EMBL:ERT02586.1};
OS   Sporothrix schenckii (strain ATCC 58251 / de Perez 2211183) (Rose-picker's
OS   disease fungus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Sordariomycetidae; Ophiostomatales; Ophiostomataceae; Sporothrix.
OX   NCBI_TaxID=1391915 {ECO:0000313|EMBL:ERT02586.1, ECO:0000313|Proteomes:UP000018087};
RN   [1] {ECO:0000313|Proteomes:UP000018087}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 58251 / de Perez 2211183
RC   {ECO:0000313|Proteomes:UP000018087};
RX   PubMed=24855299; DOI=10.1128/genomea.00446-14;
RA   Cuomo C.A., Rodriguez-Del Valle N., Perez-Sanchez L., Abouelleil A.,
RA   Goldberg J., Young S., Zeng Q., Birren B.W.;
RT   "Genome sequence of the pathogenic fungus Sporothrix schenckii (ATCC
RT   58251).";
RL   Genome Announc. 2:E0044614-E0044614(2014).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, microtubule organizing
CC       center {ECO:0000256|RuleBase:RU363050}.
CC   -!- SIMILARITY: Belongs to the TUBGCP family.
CC       {ECO:0000256|ARBA:ARBA00010337, ECO:0000256|RuleBase:RU363050}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; KI440842; ERT02586.1; -; Genomic_DNA.
DR   AlphaFoldDB; U7Q783; -.
DR   STRING; 1391915.U7Q783; -.
DR   eggNOG; KOG2065; Eukaryota.
DR   HOGENOM; CLU_005595_0_0_1; -.
DR   OrthoDB; 2729509at2759; -.
DR   Proteomes; UP000018087; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0000930; C:gamma-tubulin complex; IEA:UniProt.
DR   GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR   GO; GO:0000922; C:spindle pole; IEA:InterPro.
DR   GO; GO:0005816; C:spindle pole body; IEA:UniProt.
DR   GO; GO:0043015; F:gamma-tubulin binding; IEA:InterPro.
DR   GO; GO:0007020; P:microtubule nucleation; IEA:InterPro.
DR   Gene3D; 1.20.120.1900; Gamma-tubulin complex, C-terminal domain; 1.
DR   InterPro; IPR007259; GCP.
DR   InterPro; IPR040457; GCP_C.
DR   InterPro; IPR042241; GCP_C_sf.
DR   InterPro; IPR041470; GCP_N.
DR   PANTHER; PTHR19302; GAMMA TUBULIN COMPLEX PROTEIN; 1.
DR   PANTHER; PTHR19302:SF73; SPINDLE POLE BODY COMPONENT; 1.
DR   Pfam; PF04130; GCP_C_terminal; 1.
DR   Pfam; PF17681; GCP_N_terminal; 1.
PE   3: Inferred from homology;
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490, ECO:0000256|RuleBase:RU363050};
KW   Cytoskeleton {ECO:0000256|ARBA:ARBA00023212,
KW   ECO:0000256|RuleBase:RU363050};
KW   Microtubule {ECO:0000256|ARBA:ARBA00022701, ECO:0000256|RuleBase:RU363050};
KW   Reference proteome {ECO:0000313|Proteomes:UP000018087}.
FT   DOMAIN          2..349
FT                   /note="Gamma tubulin complex component protein N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF17681"
FT   DOMAIN          360..874
FT                   /note="Gamma tubulin complex component C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF04130"
FT   REGION          8..49
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          650..683
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          816..839
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        26..47
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        819..838
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   878 AA;  95307 MW;  E773510A2233F93C CRC64;
     MLHEILLSLS GHSSPLLRPD GPSRHGNTGA QDSSAPSLGT ASSPEPALSP SERALLSDLA
     RLSDLHIRLR AHATHIAAVH PSAVCRAVAA AVVSVHLAAF QRHVLAVEAT VLKRDPILVG
     AYDIVPLTAV VGAFADWPRR FEWLWAIVQY ILPESSASRT TMATAKSPAK VSPDTPSGSQ
     LINRLRAELQ TGYEDVERTA RSLVRVAETT WLKQVSAWIL YGRLPSFGGG DFFVQQEAST
     ADMTGEYVCV SQHLPAFVTP ATAASMLFIG RSLVHLRAKT DSRSSNGPKA SHWLSDGVVG
     SGAMTMTSTG DYHLSTQLQE LSKLTYPLDG ATFARTIAHI RAVLSRTALR KLLPPTKVVD
     MLQLLRDFYL LGRGEFAMAL VEQADETMRS RWQRSDGAGA APPTTASSVR GMAAVIVKDG
     EVAAVLARTW AMLGAMHGRN ANADQGEEED EGMELARETL RLVLQKPTTS TSTTPAARTP
     SAGATVVAGS LGNGRQRHTT LASIASTPFQ NLLFSVPASL VLQIPYPLDL VLSAADLQSY
     SAIHAYLLSI RRAHIRLTGL WKLSSLRRHH PPPPTPPYGG RGRHSLEQVQ MLRERYTTRA
     NALRSVWATT SAAIFFLAEI ENYLQIDVVV ELWDGFQKWL TIGNDEPMRG VGVSSSVSQK
     SKPAERKEDS DADVEGGNED GADEDEDIWL AEGLAAEDDT AFRMDDPVAA SHDPQSLATA
     HRRYLRRLVR RLLLDRAHWT EPLYALLVSI DQMAALVHRL QSLWLALDLE SDAGVVDAFV
     DLDREQHDVL DALAAAERGV RQGVLTVVGV LRDLEGQEDG RGEEEEEEDE EDDDGDFGGW
     ADGGLAGNGL RAAGAYVPRR VGRLDRLLMK LDFGSWGG
//