ID U7QFV0_9CYAN Unreviewed; 508 AA.
AC U7QFV0;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=Pyridine nucleotide-disulfide oxidoreductase family protein {ECO:0000313|EMBL:ERT06829.1};
GN ORFNames=M595_3260 {ECO:0000313|EMBL:ERT06829.1};
OS Lyngbya aestuarii BL J.
OC Bacteria; Cyanobacteriota; Cyanophyceae; Oscillatoriophycideae;
OC Oscillatoriales; Oscillatoriaceae; Lyngbya.
OX NCBI_TaxID=1348334 {ECO:0000313|EMBL:ERT06829.1, ECO:0000313|Proteomes:UP000017127};
RN [1] {ECO:0000313|EMBL:ERT06829.1, ECO:0000313|Proteomes:UP000017127}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BL J {ECO:0000313|EMBL:ERT06829.1,
RC ECO:0000313|Proteomes:UP000017127};
RX PubMed=24376438; DOI=10.3389/fmicb.2013.00363;
RA Kothari A., Vaughn M., Garcia-Pichel F.;
RT "Comparative genomic analyses of the cyanobacterium, Lyngbya aestuarii BL
RT J, a powerful hydrogen producer.";
RL Front. Microbiol. 4:363-363(2013).
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|PIRSR:PIRSR000137-2};
CC -!- SIMILARITY: Belongs to the GMC oxidoreductase family.
CC {ECO:0000256|ARBA:ARBA00010790}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ERT06829.1}.
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DR EMBL; AUZM01000030; ERT06829.1; -; Genomic_DNA.
DR RefSeq; WP_023067004.1; NZ_AUZM01000030.1.
DR AlphaFoldDB; U7QFV0; -.
DR PATRIC; fig|1348334.3.peg.3155; -.
DR OrthoDB; 9787779at2; -.
DR Proteomes; UP000017127; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR GO; GO:0016614; F:oxidoreductase activity, acting on CH-OH group of donors; IEA:InterPro.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 2.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR012132; GMC_OxRdtase.
DR InterPro; IPR000172; GMC_OxRdtase_N.
DR InterPro; IPR007867; GMC_OxRtase_C.
DR PANTHER; PTHR46056; LONG-CHAIN-ALCOHOL OXIDASE; 1.
DR PANTHER; PTHR46056:SF4; LONG-CHAIN-ALCOHOL OXIDASE; 1.
DR Pfam; PF05199; GMC_oxred_C; 1.
DR Pfam; PF00732; GMC_oxred_N; 1.
DR PIRSF; PIRSF000137; Alcohol_oxidase; 2.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
PE 3: Inferred from homology;
KW FAD {ECO:0000256|PIRSR:PIRSR000137-2};
KW Flavoprotein {ECO:0000256|PIRSR:PIRSR000137-2};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 7..26
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 24..305
FT /note="Glucose-methanol-choline oxidoreductase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00732"
FT DOMAIN 439..498
FT /note="Glucose-methanol-choline oxidoreductase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF05199"
FT BINDING 235
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000256|PIRSR:PIRSR000137-2"
FT BINDING 443..444
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000256|PIRSR:PIRSR000137-2"
SQ SEQUENCE 508 AA; 57083 MW; 65A00243D3EDAF82 CRC64;
MTLKQHYDLI IIGAGAGGGT LAYALASTGK NILLLERGGY LPREKSNWNP DEIFLNQRYQ
TQEKWLDSNN QSFSPEAFYF VGGNTKVYGA ALQRMRAEDF GELRHFDGIS PAWPLGYDTF
EPYYTRAESL FKLHGLRGED PTEPPATNEY PFPPFEHEPR IQEVADQLQN LGLNPYHLTL
ALNRDEQHPE NRPCIRCNTC DPYPCLVDAK CDAQVTCVDP ALKQDNVTLL MNAKVTRLIT
NNEGKIIQAV EAEIDGETQQ FSSDLVVLSC GAINSATLLL KSTNSHHPNG LANSSGLVGR
NLMLHNHSAL IAASHQPNET VFQKTLGIND FYFQGPKQDY PLGQIQLTGK TVWQRLKHMA
EGEIPQVVLE YIAKHSVDWW ITTEDLPQPE NHVTLNSQGQ IVVNYTPNNL KPHQELISTL
EQYLKQLDFY LFWTKQMPVK VVWHQAGTCK FGNDPKDSVL DLNCQTHDVN NLYVVDSSFF
PALGAVNPTL TIVANALRVA DHLKDQWG
//
