ID   U7V7E3_9MICC            Unreviewed;       966 AA.
AC   U7V7E3;
DT   22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT   22-JAN-2014, sequence version 1.
DT   24-JAN-2024, entry version 46.
DE   SubName: Full=DEAD/DEAH box helicase {ECO:0000313|EMBL:ERT67480.1};
GN   ORFNames=HMPREF0742_00385 {ECO:0000313|EMBL:ERT67480.1};
OS   Rothia aeria F0184.
OC   Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Micrococcaceae;
OC   Rothia.
OX   NCBI_TaxID=888019 {ECO:0000313|EMBL:ERT67480.1, ECO:0000313|Proteomes:UP000017174};
RN   [1] {ECO:0000313|EMBL:ERT67480.1, ECO:0000313|Proteomes:UP000017174}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=F0184 {ECO:0000313|EMBL:ERT67480.1,
RC   ECO:0000313|Proteomes:UP000017174};
RA   Weinstock G., Sodergren E., Wylie T., Fulton L., Fulton R., Fronick C.,
RA   O'Laughlin M., Godfrey J., Miner T., Herter B., Appelbaum E., Cordes M.,
RA   Lek S., Wollam A., Pepin K.H., Palsikar V.B., Mitreva M., Wilson R.K.;
RL   Submitted (AUG-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ERT67480.1}.
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DR   EMBL; AXZG01000010; ERT67480.1; -; Genomic_DNA.
DR   RefSeq; WP_023133066.1; NZ_KI518035.1.
DR   AlphaFoldDB; U7V7E3; -.
DR   PATRIC; fig|888019.4.peg.331; -.
DR   HOGENOM; CLU_002902_4_1_11; -.
DR   Proteomes; UP000017174; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   CDD; cd18795; SF2_C_Ski2; 1.
DR   Gene3D; 1.10.3380.30; -; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR001650; Helicase_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR012961; Ski2/MTR4_C.
DR   PANTHER; PTHR12131; ATP-DEPENDENT RNA AND DNA HELICASE; 1.
DR   PANTHER; PTHR12131:SF8; HELICASE SKI2W; 1.
DR   Pfam; PF00270; DEAD; 1.
DR   Pfam; PF08148; DSHCT; 1.
DR   Pfam; PF00271; Helicase_C; 1.
DR   SMART; SM00487; DEXDc; 1.
DR   SMART; SM01142; DSHCT; 1.
DR   SMART; SM00490; HELICc; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR   PROSITE; PS51194; HELICASE_CTER; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:ERT67480.1};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT   DOMAIN          46..204
FT                   /note="Helicase ATP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51192"
FT   DOMAIN          358..527
FT                   /note="Helicase C-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51194"
FT   REGION          231..319
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          583..610
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        239..257
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        297..319
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   966 AA;  107999 MW;  F4554A97CFFF63AE CRC64;
     MPNNENTSYA AQYQAAQQRA AHAKTALAAF EKNLGFPLDD FQQSACRSVE SGRAVLVAAP
     TGAGKTVVGE FGIYLALRKR LKAFYTTPIK ALSNQKYHDF VREYGEETVG LLTGDTSINA
     EAPVLVMTTE VLRNMLYADS PTLEGLGYVI LDEVHYLADR FRGAVWEEAI IHLPEHVTVI
     SLSATVSNVE EFGAWLDTVR GGTDVIVSEH RPVPLWQHML VGNQIVDLFT PDPGEKSASG
     ARRATKRPRK DADEHTAPAG MRLNPQLKQL RPGYGADRGY RGRGGKRERF RRTRKHHSTA
     QTFEDSRRTP HAAQDNPLRP HRISRPEMVR TLDKAGLLPA ICFIFSRAGC DGAVTQCIDA
     DLMLTTDEQQ RTIRAYIAEA TAHLDPRDLN TLGYYEWREG LLRGIAAHHA GMLPLFKETV
     ETLFTTGLIK LVFATETLAL GINMPARTVI LEKLTKYNGE THVDITPGEY TQLTGRAGRR
     GIDIEGHAVI AWRPNTTAAH VASLASTRTY PLNSSFRPTY NMAANLIATY GAERTRKILE
     SSFAQFQADK SVVGVAARVR KNENALAGYH ESMRCHLGDF AEYFALRRDI SALEKKAEKT
     NQRHARTQAH QSIQELLPGD IIHIPTGRLR GYAVVTTRAE SNTDPRIGIL TEDAHTRTAT
     PRDFEGIIDP VSRIKLPKRL TLKTPKERRD TASRMRQALI DHKPPRETKH RTITERPNGL
     QEQLETLRTK MRNHPCHGCS ERETHARWAE RWYKLNSDTD GLRRQIARRT NTIAHVFNRI
     AQLLTSYGYV NRATDGELTL TSTGQSLRRI YGDKDLLTCL CLEAGFLNTL DPAAIAATIA
     ALTYQGKRDT IEHLPRYPHP SLRESITTIN RELARLNASE EEHKLPQTPA CDFGLVEPIY
     AWARGAHLAK ALENTDLTAG DFVRWAKQVI DSLDQITHIN GINADLRARC EKAIILIRRG
     VIALDI
//