ID   V2JCG5_9BURK            Unreviewed;       393 AA.
AC   V2JCG5;
DT   22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT   22-JAN-2014, sequence version 1.
DT   27-MAR-2024, entry version 28.
DE   SubName: Full=Alcohol dehydrogenase {ECO:0000313|EMBL:ESJ23084.1};
GN   ORFNames=B551_0207345 {ECO:0000313|EMBL:ESJ23084.1};
OS   Cupriavidus sp. HPC(L).
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Cupriavidus.
OX   NCBI_TaxID=1217418 {ECO:0000313|EMBL:ESJ23084.1, ECO:0000313|Proteomes:UP000053474};
RN   [1] {ECO:0000313|EMBL:ESJ23084.1, ECO:0000313|Proteomes:UP000053474}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=HPC(L) {ECO:0000313|Proteomes:UP000053474};
RA   Purohit H.J., Agarwal L.;
RT   "Cupriavidus a Desert isolate.";
RL   Submitted (AUG-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000256|ARBA:ARBA00001947};
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ESJ23084.1}.
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DR   EMBL; AMPR02000092; ESJ23084.1; -; Genomic_DNA.
DR   RefSeq; WP_006579038.1; NZ_AMPR02000092.1.
DR   AlphaFoldDB; V2JCG5; -.
DR   OrthoDB; 9773078at2; -.
DR   Proteomes; UP000053474; Unassembled WGS sequence.
DR   CDD; cd08283; FDH_like_1; 1.
DR   Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR013149; ADH-like_C.
DR   InterPro; IPR013154; ADH-like_N.
DR   InterPro; IPR011032; GroES-like_sf.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   PANTHER; PTHR42813:SF2; DEHYDROGENASE, ZINC-CONTAINING, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G02810)-RELATED; 1.
DR   PANTHER; PTHR42813; ZINC-TYPE ALCOHOL DEHYDROGENASE-LIKE; 1.
DR   Pfam; PF08240; ADH_N; 1.
DR   Pfam; PF00107; ADH_zinc_N; 1.
DR   SUPFAM; SSF50129; GroES-like; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   4: Predicted;
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000053474};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT   DOMAIN          26..152
FT                   /note="Alcohol dehydrogenase-like N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF08240"
FT   DOMAIN          196..277
FT                   /note="Alcohol dehydrogenase-like C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00107"
SQ   SEQUENCE   393 AA;  43354 MW;  2F51AF6FE3F1D5F2 CRC64;
     MKALCWHGKH DIRYDTVPDP VIEHPRDAII RVSSCAICGS DLHLYDGFVP GMEHGDIMGH
     EFMGEVVEVG AQNRRLRVGD RVVVPFTIIC GECDQCRRGN FSVCERTNRN KEAADKMFGH
     TTAGLFGYTH LTGGYAGGQA EYVRVPYADV APVKVPAELS DEQVLFLGDI LPTGWQAAAQ
     CDIQPDDIVA IWGAGPVGQF CILSALLMGA KQVVVIDRVP ERLRMAQQLG PDRVTLIDFE
     NQSVLEALNE ITHGKGPDKC IDAVGLEAHA TRSLDSIYDR VKQAVMLETD RPHVLREMIY
     VCRPGGIVSI PGVYGGLVDK IPMGALMNKG LTIRTGQTHV NRWTDDLLQR IIDRQIDPTF
     VISHRVKLAD GPSMYETFRD KHDGCIKVVM TPA
//