ID V2TSS1_9GAMM Unreviewed; 488 AA.
AC V2TSS1;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=Guanylate cyclase domain-containing protein {ECO:0000259|PROSITE:PS50125};
GN ORFNames=P256_00374 {ECO:0000313|EMBL:ESK40946.1};
OS Acinetobacter nectaris CIP 110549.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Moraxellales; Moraxellaceae;
OC Acinetobacter.
OX NCBI_TaxID=1392540 {ECO:0000313|EMBL:ESK40946.1, ECO:0000313|Proteomes:UP000023785};
RN [1] {ECO:0000313|EMBL:ESK40946.1, ECO:0000313|Proteomes:UP000023785}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CIP 110549 {ECO:0000313|EMBL:ESK40946.1,
RC ECO:0000313|Proteomes:UP000023785};
RG The Broad Institute Genomics Platform;
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Cerqueira G., Feldgarden M., Courvalin P., Grillot-Courvalin C.,
RA Clermont D., Rocha E., Yoon E.-J., Nemec A., Young S.K., Zeng Q.,
RA Gargeya S., Fitzgerald M., Abouelleil A., Alvarado L., Berlin A.M.,
RA Chapman S.B., Gainer-Dewar J., Goldberg J., Gnerre S., Griggs A., Gujja S.,
RA Hansen M., Howarth C., Imamovic A., Ireland A., Larimer J., McCowan C.,
RA Murphy C., Pearson M., Poon T.W., Priest M., Roberts A., Saif S., Shea T.,
RA Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Acinetobacter nectaris CIP 110549.";
RL Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ESK40946.1}.
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DR EMBL; AYER01000002; ESK40946.1; -; Genomic_DNA.
DR RefSeq; WP_023271977.1; NZ_KI530712.1.
DR AlphaFoldDB; V2TSS1; -.
DR STRING; 1392540.P256_00374; -.
DR PATRIC; fig|1392540.3.peg.365; -.
DR eggNOG; COG2114; Bacteria.
DR HOGENOM; CLU_047397_0_0_6; -.
DR OrthoDB; 9806704at2; -.
DR Proteomes; UP000023785; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004016; F:adenylate cyclase activity; IEA:UniProt.
DR GO; GO:0009190; P:cyclic nucleotide biosynthetic process; IEA:InterPro.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR CDD; cd07302; CHD; 1.
DR Gene3D; 3.30.70.1230; Nucleotide cyclase; 1.
DR InterPro; IPR001054; A/G_cyclase.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR PANTHER; PTHR43081:SF16; ADENYLATE CYCLASE, TERMINAL-DIFFERENTIATION SPECIFIC; 1.
DR PANTHER; PTHR43081; ADENYLATE CYCLASE, TERMINAL-DIFFERENTIATION SPECIFIC-RELATED; 1.
DR Pfam; PF00211; Guanylate_cyc; 1.
DR SMART; SM00044; CYCc; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR PROSITE; PS50125; GUANYLATE_CYCLASE_2; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000023785};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 16..36
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 42..63
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 75..97
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 117..139
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 151..169
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 227..361
FT /note="Guanylate cyclase"
FT /evidence="ECO:0000259|PROSITE:PS50125"
SQ SEQUENCE 488 AA; 56930 MW; DD1FDDD045878FAB CRC64;
MSFDRVINNR FVVESLYRLM AYLLLSLGVL LYYFAVPLQL QHLIVPILSL IIFPLSLKLF
FYVKYEFNEF YARQVLFILD SIIVAVALAS THFSIVFSAL TLTTLWCVKS LTKISFFTYS
FAFIISLIVI YLNAIIFFGF ENYFALDSLR LAIYSLICFL LYLGSGFYFN KQYIHHLENT
KDYYQEQMNR YVQFSTQLSR YAPNQLWQSI MSGQTQAKIE YKRKKMTVFF SDIQGFTELS
EKLIPDDLAF VLNDYLSHMT EIAKKYEATL DKFIGDGVLI FFGDPHSNGI EQDAKNCIEM
AISMRQQMHV LRERWLKMGF PELHVRMGVS TGYCHVGNYG SDYRMSYTVI GHDVNLASRL
QGVADIDEIL IADSTYNLIK DEFICIPKQS IKLKGLQNST DTWQVLDKYT GIKSETQKWF
DYEYKGFHLL LNLEEVQHYE YDNLVTVLEK AITRIEQQKS ITTENGVARL RLEDQVVEIV
DIHKKPPY
//
