ID V2WPB8_MONRO Unreviewed; 662 AA.
AC V2WPB8;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE RecName: Full=RNA-directed DNA polymerase {ECO:0000256|ARBA:ARBA00012493};
DE EC=2.7.7.49 {ECO:0000256|ARBA:ARBA00012493};
GN ORFNames=Moror_13406 {ECO:0000313|EMBL:ESK82075.1};
OS Moniliophthora roreri (strain MCA 2997) (Cocoa frosty pod rot fungus)
OS (Crinipellis roreri).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Agaricomycetidae; Agaricales; Marasmiineae; Marasmiaceae; Moniliophthora.
OX NCBI_TaxID=1381753 {ECO:0000313|EMBL:ESK82075.1, ECO:0000313|Proteomes:UP000017559};
RN [1] {ECO:0000313|EMBL:ESK82075.1, ECO:0000313|Proteomes:UP000017559}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MCA 2997 {ECO:0000313|EMBL:ESK82075.1,
RC ECO:0000313|Proteomes:UP000017559};
RX PubMed=24571091; DOI=10.1186/1471-2164-15-164;
RA Meinhardt L.W., Costa G.G.L., Thomazella D.P.T., Teixeira P.J.P.L.,
RA Carazzolle M.F., Schuster S.C., Carlson J.E., Guiltinan M.J.,
RA Mieczkowski P., Farmer A., Ramaraj T., Crozier J., Davis R.E., Shao J.,
RA Melnick R.L., Pereira G.A.G., Bailey B.A.;
RT "Genome and secretome analysis of the hemibiotrophic fungal pathogen,
RT Moniliophthora roreri, which causes frosty pod rot disease of cacao:
RT mechanisms of the biotrophic and necrotrophic phases.";
RL BMC Genomics 15:164-164(2014).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ESK82075.1}.
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DR EMBL; AWSO01002082; ESK82075.1; -; Genomic_DNA.
DR RefSeq; XP_007858624.1; XM_007860433.1.
DR AlphaFoldDB; V2WPB8; -.
DR KEGG; mrr:Moror_13406; -.
DR HOGENOM; CLU_000384_33_2_1; -.
DR Proteomes; UP000017559; Unassembled WGS sequence.
DR GO; GO:0003964; F:RNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
DR CDD; cd00303; retropepsin_like; 1.
DR CDD; cd09274; RNase_HI_RT_Ty3; 1.
DR CDD; cd01647; RT_LTR; 1.
DR Gene3D; 3.30.70.270; -; 2.
DR Gene3D; 2.40.70.10; Acid Proteases; 1.
DR Gene3D; 3.10.10.10; HIV Type 1 Reverse Transcriptase, subunit A, domain 1; 1.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR021109; Peptidase_aspartic_dom_sf.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR InterPro; IPR000477; RT_dom.
DR InterPro; IPR041373; RT_RNaseH.
DR PANTHER; PTHR24559:SF437; RIBONUCLEASE H; 1.
DR PANTHER; PTHR24559; TRANSPOSON TY3-I GAG-POL POLYPROTEIN; 1.
DR Pfam; PF17917; RT_RNaseH; 1.
DR Pfam; PF08284; RVP_2; 1.
DR Pfam; PF00078; RVT_1; 1.
DR SUPFAM; SSF50630; Acid proteases; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR PROSITE; PS50878; RT_POL; 1.
PE 4: Predicted;
KW Nucleotidyltransferase {ECO:0000313|EMBL:ESK82075.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000017559};
KW RNA-directed DNA polymerase {ECO:0000313|EMBL:ESK82075.1};
KW Transferase {ECO:0000313|EMBL:ESK82075.1}.
FT DOMAIN 230..411
FT /note="Reverse transcriptase"
FT /evidence="ECO:0000259|PROSITE:PS50878"
SQ SEQUENCE 662 AA; 76757 MW; C293A78059C6F994 CRC64;
MDRNSMHIPL KYKVGTKNIE TKALLDSGAG GRFISMGLAR TLGKRWIQLP EKIRVFNVDG
TANKTAWITH IVELEFQIAG KEFRENFMIS GIGDEDMILG LPWLRHHNPV IDWETGEIQF
QPRWRIQIKR FRGVLDNLEP EVLIGAKTTV SQEMAHQHQT VKKEIEDLIP SYLLGYRDCF
EKGKAERFPP TRTYGHAIDL KPDFVPRNCK LYPLSPAEQQ EQDKFLEENL WKGYIHKLKS
PMASLFFFVA KKEKGALRPT QDYRELNKGT VKNTYPLLLI LELLGRLKGA TIFTKLDLRN
RYNNVRIKDG DQWKAAFKTN RGLFEPTVMF FGLSNSPATF QAFMNDILSD FIDEGWCVVY
MDDILIFSKD QAEHKERTER LMRRLKEHDL FLKPEKCEFD MTEVVFLGMV IRPGYIAMDP
VKLAGIADWE PPQAVKGVRV FLGFGNFYRK FIGKYAHLTR PLNDLLQKNR KFDWTTQCQL
AFELLKTKFL SEPILVMPDV DKPFVIEADA LKWATGAVLR QKGVDGEWHP CGYLSKSFSP
TERNYEIYDR ELLVIYRALM EWRHYLMGGK FKVVVLSDHK NLTYFRMAQK LNRRQARWSL
FLSEVDLGLV HVPGKSISQA DALSRRSNEQ DDVDSDNEDI VVLPDRLFIK GIDLGLKEDI
AE
//
