ID V4A214_LOTGI Unreviewed; 469 AA.
AC V4A214;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE RecName: Full=Receptor ligand binding region domain-containing protein {ECO:0000259|Pfam:PF01094};
GN ORFNames=LOTGIDRAFT_103681 {ECO:0000313|EMBL:ESO97858.1};
OS Lottia gigantea (Giant owl limpet).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC Patellogastropoda; Lottioidea; Lottiidae; Lottia.
OX NCBI_TaxID=225164 {ECO:0000313|EMBL:ESO97858.1, ECO:0000313|Proteomes:UP000030746};
RN [1] {ECO:0000313|EMBL:ESO97858.1, ECO:0000313|Proteomes:UP000030746}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23254933; DOI=10.1038/nature11696;
RA Simakov O., Marletaz F., Cho S.J., Edsinger-Gonzales E., Havlak P.,
RA Hellsten U., Kuo D.H., Larsson T., Lv J., Arendt D., Savage R.,
RA Osoegawa K., de Jong P., Grimwood J., Chapman J.A., Shapiro H., Aerts A.,
RA Otillar R.P., Terry A.Y., Boore J.L., Grigoriev I.V., Lindberg D.R.,
RA Seaver E.C., Weisblat D.A., Putnam N.H., Rokhsar D.S.;
RT "Insights into bilaterian evolution from three spiralian genomes.";
RL Nature 493:526-531(2013).
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DR EMBL; KB201304; ESO97858.1; -; Genomic_DNA.
DR RefSeq; XP_009051699.1; XM_009053451.1.
DR AlphaFoldDB; V4A214; -.
DR STRING; 225164.V4A214; -.
DR EnsemblMetazoa; LotgiT103681; LotgiP103681; LotgiG103681.
DR GeneID; 20229772; -.
DR KEGG; lgi:LOTGIDRAFT_103681; -.
DR CTD; 20229772; -.
DR HOGENOM; CLU_005389_2_4_1; -.
DR OMA; FWKEADK; -.
DR OrthoDB; 2952216at2759; -.
DR Proteomes; UP000030746; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:InterPro.
DR Gene3D; 3.40.50.2300; -; 2.
DR InterPro; IPR001828; ANF_lig-bd_rcpt.
DR InterPro; IPR000337; GPCR_3.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR24060:SF134; G_PROTEIN_RECEP_F3_4 DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR24060; METABOTROPIC GLUTAMATE RECEPTOR; 1.
DR Pfam; PF01094; ANF_receptor; 1.
DR PRINTS; PR00248; GPCRMGR.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000030746};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT DOMAIN 54..450
FT /note="Receptor ligand binding region"
FT /evidence="ECO:0000259|Pfam:PF01094"
SQ SEQUENCE 469 AA; 52475 MW; C4FC4C3C71E0FF43 CRC64;
MFLDYRTIYF HSVFYLLSHP TISFNYFSGL FDVHEKSVNP FLCGKVNTLH GFQLLEAFHY
ALGLVNNKQG IFADKLQGVQ VGGIGLDGCQ SDIRSGFLVS NIHNGMVSLV KNGKTIDPKE
IDAYIGTYSS DSSIYVNRIL NDLNIPQVSY ASSSTQLKDQ LRYPYFYRTV PADDNQAEAM
VDFLDKHNIR YVQVLYTDTS YGILGSKAFE EAASRKRICV AQMVSYPDEG IVSNEISNDV
VTALLQKPVA NTVVVFAGTN YINALLKAVG RVAGDTSPFK FIGSETWGNS EDAIIGSEKY
ASGSVSLGLE TVNLKVFDEY LGKKTPLNSQ GNPWFSEYYE EIWDCYLSVP SVNRQKECAQ
TARSIPLSTQ YRQDPGVLHV INAVFSSALA LDKALTEVCG EGYTTVCEAY KNRNDRRDVL
LKKLDSVEFE DLSKTNFKFE NREGNKGYDF YSITIQSVTS GYIYKKVRM
//
