ID V4A2Z3_LOTGI Unreviewed; 359 AA.
AC V4A2Z3;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE RecName: Full=Nucleoporin SEH1 {ECO:0008006|Google:ProtNLM};
GN ORFNames=LOTGIDRAFT_191563 {ECO:0000313|EMBL:ESO91072.1};
OS Lottia gigantea (Giant owl limpet).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC Patellogastropoda; Lottioidea; Lottiidae; Lottia.
OX NCBI_TaxID=225164 {ECO:0000313|EMBL:ESO91072.1, ECO:0000313|Proteomes:UP000030746};
RN [1] {ECO:0000313|EMBL:ESO91072.1, ECO:0000313|Proteomes:UP000030746}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23254933; DOI=10.1038/nature11696;
RA Simakov O., Marletaz F., Cho S.J., Edsinger-Gonzales E., Havlak P.,
RA Hellsten U., Kuo D.H., Larsson T., Lv J., Arendt D., Savage R.,
RA Osoegawa K., de Jong P., Grimwood J., Chapman J.A., Shapiro H., Aerts A.,
RA Otillar R.P., Terry A.Y., Boore J.L., Grigoriev I.V., Lindberg D.R.,
RA Seaver E.C., Weisblat D.A., Putnam N.H., Rokhsar D.S.;
RT "Insights into bilaterian evolution from three spiralian genomes.";
RL Nature 493:526-531(2013).
CC -!- SIMILARITY: Belongs to the WD repeat SEC13 family.
CC {ECO:0000256|ARBA:ARBA00010102}.
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DR EMBL; KB202284; ESO91072.1; -; Genomic_DNA.
DR RefSeq; XP_009058341.1; XM_009060093.1.
DR AlphaFoldDB; V4A2Z3; -.
DR STRING; 225164.V4A2Z3; -.
DR EnsemblMetazoa; LotgiT191563; LotgiP191563; LotgiG191563.
DR GeneID; 20244939; -.
DR KEGG; lgi:LOTGIDRAFT_191563; -.
DR CTD; 20244939; -.
DR HOGENOM; CLU_032441_1_2_1; -.
DR OMA; EWECTAR; -.
DR OrthoDB; 177928at2759; -.
DR Proteomes; UP000030746; Unassembled WGS sequence.
DR GO; GO:0005764; C:lysosome; IEA:UniProtKB-KW.
DR GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR037363; Sec13/Seh1_fam.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR11024; NUCLEAR PORE COMPLEX PROTEIN SEC13 / SEH1 FAMILY MEMBER; 1.
DR PANTHER; PTHR11024:SF3; NUCLEOPORIN SEH1; 1.
DR Pfam; PF00400; WD40; 4.
DR SMART; SM00320; WD40; 5.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 2.
DR PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE 3: Inferred from homology;
KW Lysosome {ECO:0000256|ARBA:ARBA00023228};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000030746};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transport {ECO:0000256|ARBA:ARBA00022927};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT REPEAT 8..40
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 273..305
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
SQ SEQUENCE 359 AA; 40657 MW; B1440B5243636CEA CRC64;
MFETNPFPAS HEDLIHDVKY DFHGKRKATC SSDHSVKIWD CDEKGQWHCS ANWKAHSGSV
WRVTWCHPEY GQVIATCSFD RTAAVWEELI GEHARQNKQS HWVKRTSLVD SRTSVTDVKF
APRHLGLQLA TCSADCVVRI YEAHDVMNLS QWSLQHEIQC SLSCSCLAWN PSLSRSHPPM
ICVGSDNPST TAGGKVQIYE YSDSNRKWRK LEIISIVTDP VHDLEFAPNL GRSYHLLAVA
SKDLNLFSIK PLSSSLKDSA NISKFDIQRL GEFTEHKSQV WRISWNVFGT VLTSSGDDGC
VRLWKANYMG IWKCVQVLED GSRKAVASYE TKTVPVTSNN SVRYYHIKPV ANASQAIWH
//
