ID V4A8N1_LOTGI Unreviewed; 269 AA.
AC V4A8N1;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE RecName: Full=Gelsolin-like domain-containing protein {ECO:0000259|Pfam:PF00626};
DE Flags: Fragment;
GN ORFNames=LOTGIDRAFT_105757 {ECO:0000313|EMBL:ESO91380.1};
OS Lottia gigantea (Giant owl limpet).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC Patellogastropoda; Lottioidea; Lottiidae; Lottia.
OX NCBI_TaxID=225164 {ECO:0000313|EMBL:ESO91380.1, ECO:0000313|Proteomes:UP000030746};
RN [1] {ECO:0000313|EMBL:ESO91380.1, ECO:0000313|Proteomes:UP000030746}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23254933; DOI=10.1038/nature11696;
RA Simakov O., Marletaz F., Cho S.J., Edsinger-Gonzales E., Havlak P.,
RA Hellsten U., Kuo D.H., Larsson T., Lv J., Arendt D., Savage R.,
RA Osoegawa K., de Jong P., Grimwood J., Chapman J.A., Shapiro H., Aerts A.,
RA Otillar R.P., Terry A.Y., Boore J.L., Grigoriev I.V., Lindberg D.R.,
RA Seaver E.C., Weisblat D.A., Putnam N.H., Rokhsar D.S.;
RT "Insights into bilaterian evolution from three spiralian genomes.";
RL Nature 493:526-531(2013).
CC -!- SIMILARITY: Belongs to the villin/gelsolin family.
CC {ECO:0000256|ARBA:ARBA00008418}.
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DR EMBL; KB202283; ESO91380.1; -; Genomic_DNA.
DR RefSeq; XP_009058073.1; XM_009059825.1.
DR AlphaFoldDB; V4A8N1; -.
DR STRING; 225164.V4A8N1; -.
DR EnsemblMetazoa; LotgiT105757; LotgiP105757; LotgiG105757.
DR GeneID; 20230026; -.
DR KEGG; lgi:LOTGIDRAFT_105757; -.
DR CTD; 20230026; -.
DR HOGENOM; CLU_002568_4_1_1; -.
DR OMA; EIMNHES; -.
DR OrthoDB; 25995at2759; -.
DR Proteomes; UP000030746; Unassembled WGS sequence.
DR GO; GO:0051015; F:actin filament binding; IEA:InterPro.
DR CDD; cd11290; gelsolin_S1_like; 1.
DR Gene3D; 3.40.20.10; Severin; 2.
DR InterPro; IPR029006; ADF-H/Gelsolin-like_dom_sf.
DR InterPro; IPR007123; Gelsolin-like_dom.
DR InterPro; IPR007122; Villin/Gelsolin.
DR PANTHER; PTHR11977:SF85; HP DOMAIN-CONTAINING PROTEIN-RELATED; 1.
DR PANTHER; PTHR11977; VILLIN; 1.
DR Pfam; PF00626; Gelsolin; 2.
DR PRINTS; PR00597; GELSOLIN.
DR SMART; SM00262; GEL; 2.
DR SUPFAM; SSF55753; Actin depolymerizing proteins; 2.
PE 3: Inferred from homology;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Reference proteome {ECO:0000313|Proteomes:UP000030746};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 64..136
FT /note="Gelsolin-like"
FT /evidence="ECO:0000259|Pfam:PF00626"
FT DOMAIN 177..226
FT /note="Gelsolin-like"
FT /evidence="ECO:0000259|Pfam:PF00626"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ESO91380.1"
SQ SEQUENCE 269 AA; 31021 MW; 519E935FED50190F CRC64;
GLVKAKKYDW KDSNMALFGS DTEKQVKKES AEGEPAWQGA GQEVGLKIWR VEQFEIKDWP
KEEYGKFYNG DSYIILNTYT DGESDGLLFD VHFWIGKNSS QDEYGTAAYK TVELDTFLDD
AAVQHREVQG HESELFKSYF EEIVTMEGGA KTGFRHVTPE EYRTRLMHFS GTRRHITVRE
VPLNREIIKS SDCYILDKGM KLIQFNGSEC SKDEKFKAMM YLNKVKSERG GADSETIEEA
DTPSGVSYDP LFYERHFNFK IHTETICRV
//
