ID V4AE01_LOTGI Unreviewed; 633 AA.
AC V4AE01;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE RecName: Full=STAS domain-containing protein {ECO:0000259|PROSITE:PS50801};
DE Flags: Fragment;
GN ORFNames=LOTGIDRAFT_63093 {ECO:0000313|EMBL:ESO91561.1};
OS Lottia gigantea (Giant owl limpet).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC Patellogastropoda; Lottioidea; Lottiidae; Lottia.
OX NCBI_TaxID=225164 {ECO:0000313|EMBL:ESO91561.1, ECO:0000313|Proteomes:UP000030746};
RN [1] {ECO:0000313|EMBL:ESO91561.1, ECO:0000313|Proteomes:UP000030746}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23254933; DOI=10.1038/nature11696;
RA Simakov O., Marletaz F., Cho S.J., Edsinger-Gonzales E., Havlak P.,
RA Hellsten U., Kuo D.H., Larsson T., Lv J., Arendt D., Savage R.,
RA Osoegawa K., de Jong P., Grimwood J., Chapman J.A., Shapiro H., Aerts A.,
RA Otillar R.P., Terry A.Y., Boore J.L., Grigoriev I.V., Lindberg D.R.,
RA Seaver E.C., Weisblat D.A., Putnam N.H., Rokhsar D.S.;
RT "Insights into bilaterian evolution from three spiralian genomes.";
RL Nature 493:526-531(2013).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141,
CC ECO:0000256|RuleBase:RU362052}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU362052}.
CC -!- SIMILARITY: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
CC {ECO:0000256|RuleBase:RU362052}.
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DR EMBL; KB202237; ESO91561.1; -; Genomic_DNA.
DR RefSeq; XP_009057598.1; XM_009059350.1.
DR AlphaFoldDB; V4AE01; -.
DR EnsemblMetazoa; LotgiT63093; LotgiP63093; LotgiG63093.
DR GeneID; 20251665; -.
DR KEGG; lgi:LOTGIDRAFT_63093; -.
DR CTD; 20251665; -.
DR HOGENOM; CLU_003182_9_5_1; -.
DR OMA; HRNDANI; -.
DR OrthoDB; 161900at2759; -.
DR Proteomes; UP000030746; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008509; F:monoatomic anion transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR GO; GO:0008271; F:secondary active sulfate transmembrane transporter activity; IEA:InterPro.
DR CDD; cd07042; STAS_SulP_like_sulfate_transporter; 1.
DR Gene3D; 3.30.750.24; STAS domain; 1.
DR InterPro; IPR018045; S04_transporter_CS.
DR InterPro; IPR011547; SLC26A/SulP_dom.
DR InterPro; IPR001902; SLC26A/SulP_fam.
DR InterPro; IPR002645; STAS_dom.
DR InterPro; IPR036513; STAS_dom_sf.
DR NCBIfam; TIGR00815; sulP; 1.
DR PANTHER; PTHR11814:SF257; ANION TRANSPORTER SULP-7D; 1.
DR PANTHER; PTHR11814; SULFATE TRANSPORTER; 1.
DR Pfam; PF01740; STAS; 1.
DR Pfam; PF00916; Sulfate_transp; 1.
DR SUPFAM; SSF52091; SpoIIaa-like; 1.
DR PROSITE; PS01130; SLC26A; 1.
DR PROSITE; PS50801; STAS; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU362052};
KW Reference proteome {ECO:0000313|Proteomes:UP000030746};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU362052};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU362052}; Transport {ECO:0000256|RuleBase:RU362052}.
FT TRANSMEM 40..60
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362052"
FT TRANSMEM 67..88
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362052"
FT TRANSMEM 141..159
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362052"
FT TRANSMEM 166..186
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362052"
FT TRANSMEM 225..242
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362052"
FT TRANSMEM 254..271
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362052"
FT TRANSMEM 299..319
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362052"
FT TRANSMEM 379..412
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362052"
FT TRANSMEM 433..465
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362052"
FT DOMAIN 489..633
FT /note="STAS"
FT /evidence="ECO:0000259|PROSITE:PS50801"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ESO91561.1"
FT NON_TER 633
FT /evidence="ECO:0000313|EMBL:ESO91561.1"
SQ SEQUENCE 633 AA; 69231 MW; FB7A16C49679729E CRC64;
KKMKSLCSCS VQSLITSLLA FFPIIKVVTS YRLKFIVNDV LAGLSAGFIH LPLGLGLGLL
ASLQPVYGLY TSFYPVLLYL VFGTSPHISM GTNALFAVLT ASIVEREAEI FQSGIVASNL
SNSDVNSTMT AEVILEYKVD VAMAVTFLAG AILLVMGFLR LGFLTSYLSV SFIGGFTTAS
AVHIATSQIG KMLNIKIRPY AGAGKLVKTY IDIFSRIAST NLGDLFVALV SMFILLGVKI
GINERFKAKL KIPIPIDLIL VIVSTMISYF ANFQDNYGVA IVGNVPTGMP APRLPNLEII
PRVATDGFVI AILVFALTIA MAKLMARLND YEINDNQELI AYGMSNFISS FFLCFPSCTA
PPRTMILQSL GSKTTLNGIV SAIFILIILL AAGPLFASLP VAVLAAMIVV AMKNLLLQLL
NLPGIWRVSK PDFIIWLATF LVGVLVDLDI GIVVGVSVSI LSIILQNQLS RGYTVSLPDG
EQIFLDKSYK TAADDLPRVR IFTFQSQLYF VNAERFKKLL YKNVFNPKSL KSCKEIATSD
AEVKSGNEAP DHEAPPKDEG EIIQYIILDC VYMTYIDLSG VNILKQIISE YDHVGVSIYL
TRLPRSTLNT LERSALFSDF DRSNVFYDIY DAL
//
