ID V4M218_EUTSA Unreviewed; 812 AA.
AC V4M218;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE RecName: Full=HMA domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=EUTSA_v10000049mg {ECO:0000313|EMBL:ESQ46263.1};
OS Eutrema salsugineum (Saltwater cress) (Sisymbrium salsugineum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Eutremeae; Eutrema.
OX NCBI_TaxID=72664 {ECO:0000313|EMBL:ESQ46263.1, ECO:0000313|Proteomes:UP000030689};
RN [1] {ECO:0000313|EMBL:ESQ46263.1, ECO:0000313|Proteomes:UP000030689}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23518688; DOI=10.3389/fpls.2013.00046;
RA Yang R., Jarvis D.E., Chen H., Beilstein M.A., Grimwood J., Jenkins J.,
RA Shu S., Prochnik S., Xin M., Ma C., Schmutz J., Wing R.A.,
RA Mitchell-Olds T., Schumaker K.S., Wang X.;
RT "The Reference Genome of the Halophytic Plant Eutrema salsugineum.";
RL Front. Plant Sci. 4:46-46(2013).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|RuleBase:RU362081}.
CC -!- SIMILARITY: Belongs to the cation transport ATPase (P-type) (TC 3.A.3)
CC family. Type IB subfamily. {ECO:0000256|RuleBase:RU362081}.
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DR EMBL; KI517426; ESQ46263.1; -; Genomic_DNA.
DR RefSeq; XP_006404810.1; XM_006404747.1.
DR AlphaFoldDB; V4M218; -.
DR STRING; 72664.V4M218; -.
DR EnsemblPlants; ESQ46263; ESQ46263; EUTSA_v10000049mg.
DR GeneID; 18021981; -.
DR Gramene; ESQ46263; ESQ46263; EUTSA_v10000049mg.
DR KEGG; eus:EUTSA_v10000049mg; -.
DR eggNOG; KOG0207; Eukaryota.
DR OMA; RACGIRR; -.
DR OrthoDB; 1711at2759; -.
DR Proteomes; UP000030689; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0019829; F:ATPase-coupled monoatomic cation transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd02079; P-type_ATPase_HM; 1.
DR Gene3D; 3.40.1110.10; Calcium-transporting ATPase, cytoplasmic domain N; 1.
DR Gene3D; 2.70.150.10; Calcium-transporting ATPase, cytoplasmic transduction domain A; 1.
DR Gene3D; 3.40.50.1000; HAD superfamily/HAD-like; 1.
DR InterPro; IPR023299; ATPase_P-typ_cyto_dom_N.
DR InterPro; IPR018303; ATPase_P-typ_P_site.
DR InterPro; IPR023298; ATPase_P-typ_TM_dom_sf.
DR InterPro; IPR008250; ATPase_P-typ_transduc_dom_A_sf.
DR InterPro; IPR036412; HAD-like_sf.
DR InterPro; IPR023214; HAD_sf.
DR InterPro; IPR027256; P-typ_ATPase_IB.
DR InterPro; IPR001757; P_typ_ATPase.
DR InterPro; IPR044492; P_typ_ATPase_HD_dom.
DR NCBIfam; TIGR01525; ATPase-IB_hvy; 1.
DR NCBIfam; TIGR01494; ATPase_P-type; 2.
DR PANTHER; PTHR43079:SF3; HMA DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR43079; PROBABLE CADMIUM/ZINC-TRANSPORTING ATPASE HMA1; 1.
DR Pfam; PF00122; E1-E2_ATPase; 1.
DR Pfam; PF00702; Hydrolase; 1.
DR PRINTS; PR00119; CATATPASE.
DR SFLD; SFLDS00003; Haloacid_Dehalogenase; 1.
DR SFLD; SFLDF00027; p-type_atpase; 1.
DR SUPFAM; SSF81653; Calcium ATPase, transduction domain A; 1.
DR SUPFAM; SSF81665; Calcium ATPase, transmembrane domain M; 1.
DR SUPFAM; SSF56784; HAD-like; 1.
DR PROSITE; PS00154; ATPASE_E1_E2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|RuleBase:RU362081};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU362081};
KW Metal-binding {ECO:0000256|RuleBase:RU362081};
KW Nucleotide-binding {ECO:0000256|RuleBase:RU362081};
KW Reference proteome {ECO:0000313|Proteomes:UP000030689};
KW Translocase {ECO:0000256|ARBA:ARBA00022967};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU362081};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU362081}.
FT TRANSMEM 118..138
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362081"
FT TRANSMEM 150..168
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362081"
FT TRANSMEM 175..195
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362081"
FT TRANSMEM 359..381
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362081"
FT TRANSMEM 393..415
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362081"
FT TRANSMEM 735..758
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362081"
SQ SEQUENCE 812 AA; 88101 MW; DB7EE54C91B1761D CRC64;
MEAANLIQHY SSLTRFPFPV KPTLRLARPN SFLLLPIYTS ASLRLPRRSI RILTKSACEN
HNHDHHHHHH EHDHDHHHHH RHCCSVELTV SNHPQKTLIE FAKAIGWIRL ANFLRNHLHL
CCSSAILFIA AAACPYLIPK PYIKPIQNSF MIVAFPLIGI SASLDALMDL AGGKVNIHVL
MALAAFASVF MGNALEGGLL LSMFNLAHIA EEFFTSKSMV DVKELKESNP DSALVIDVDD
DDDNAPNFFD LSYKSVHVHN VQVGSYILVG TGEIVPVDCQ VYQGNATITI EHLTGEVKPL
EVKAGDRVPG GARNLDGRII VKATKAWNES TLNKILQLTE EANSNKPKLQ RWLDEFGEVY
SKVVVVSSVA IAFLGPILFK WPFLGTAACR GSVYRALGLM VAASPCALAV APLAYATAIS
SCARKGILLK GGQVLDALAS CHTIGFDKTG TLTTGGLTCK AIEPIYGHEA GNDASVTPCC
MENCEKEALA IVAAMEKGTT HPIGRAMVDH SVGKDLPTVS VESFEYFPGR GLTATVNCIE
SVTEDSKHQK ASLGSVEFIT SLFTSQDESR KIKDAVNSSL YGNDFVHAVL SLDQKVTLIH
LEDQPRPEVS KVIAELKSRG RLRIMMLTGD HESSARRVAN AVGIDEVYYN LKPEDKLNHV
KNISRDSGGG LIMVGEGIND GPALAAATVG IVLAQRASGT AIAVADVLLL RDNITGVAFC
IAKSHQTTLL VKQNVAIALI SIFLAALPSV LGFLPLWLTV LLHEGGTLLV CLNSIRGLND
PSWSWKQDIA HMISNFNSRR SISHTNSLST AH
//
