ID V4ME15_EUTSA Unreviewed; 397 AA.
AC V4ME15;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=Auxin efflux carrier family protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=EUTSA_v10022717mg {ECO:0000313|EMBL:ESQ50753.1};
OS Eutrema salsugineum (Saltwater cress) (Sisymbrium salsugineum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Eutremeae; Eutrema.
OX NCBI_TaxID=72664 {ECO:0000313|EMBL:ESQ50753.1, ECO:0000313|Proteomes:UP000030689};
RN [1] {ECO:0000313|EMBL:ESQ50753.1, ECO:0000313|Proteomes:UP000030689}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23518688; DOI=10.3389/fpls.2013.00046;
RA Yang R., Jarvis D.E., Chen H., Beilstein M.A., Grimwood J., Jenkins J.,
RA Shu S., Prochnik S., Xin M., Ma C., Schmutz J., Wing R.A.,
RA Mitchell-Olds T., Schumaker K.S., Wang X.;
RT "The Reference Genome of the Halophytic Plant Eutrema salsugineum.";
RL Front. Plant Sci. 4:46-46(2013).
CC -!- FUNCTION: Involved in cellular auxin homeostasis by regulating auxin
CC metabolism. Regulates intracellular auxin accumulation at the
CC endoplasmic reticulum and thus auxin availability for nuclear auxin
CC signaling. {ECO:0000256|ARBA:ARBA00025100}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the auxin efflux carrier (TC 2.A.69.2) family.
CC {ECO:0000256|ARBA:ARBA00025752}.
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DR EMBL; KI517392; ESQ50753.1; -; Genomic_DNA.
DR RefSeq; XP_006409300.1; XM_006409237.1.
DR AlphaFoldDB; V4ME15; -.
DR STRING; 72664.V4ME15; -.
DR EnsemblPlants; ESQ50753; ESQ50753; EUTSA_v10022717mg.
DR GeneID; 18026087; -.
DR Gramene; ESQ50753; ESQ50753; EUTSA_v10022717mg.
DR KEGG; eus:EUTSA_v10022717mg; -.
DR eggNOG; KOG2722; Eukaryota.
DR OMA; GSDPMLW; -.
DR OrthoDB; 297188at2759; -.
DR Proteomes; UP000030689; Unassembled WGS sequence.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:EnsemblPlants.
DR GO; GO:0010329; F:auxin efflux transmembrane transporter activity; IEA:EnsemblPlants.
DR GO; GO:0009734; P:auxin-activated signaling pathway; IEA:UniProtKB-KW.
DR GO; GO:0080162; P:endoplasmic reticulum to cytosol auxin transport; IEA:InterPro.
DR GO; GO:0140964; P:intracellular auxin homeostasis; IEA:EnsemblPlants.
DR GO; GO:0010311; P:lateral root formation; IEA:EnsemblPlants.
DR GO; GO:0040009; P:regulation of growth rate; IEA:EnsemblPlants.
DR InterPro; IPR004776; Mem_transp_PIN-like.
DR InterPro; IPR045033; PILS1/3/4/5/7.
DR PANTHER; PTHR31651:SF32; (RAPE) HYPOTHETICAL PROTEIN; 1.
DR PANTHER; PTHR31651; TRANSPORTER; 1.
DR Pfam; PF03547; Mem_trans; 1.
PE 3: Inferred from homology;
KW Auxin signaling pathway {ECO:0000256|ARBA:ARBA00023294};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000030689};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..26
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 46..64
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 70..94
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 106..127
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 147..168
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 304..324
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 344..363
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 375..396
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 397 AA; 43490 MW; 0B68F9B6A6C734A8 CRC64;
MGFFSLLEVA SMPVIQVLII SLVGAFLATD RCKLFPVEAR NSMNKVVFVI FAPALMFANL
AQTVTLQDMI SWWFMPVNMG LTFLIGGILG WMVVKILKPP PYLEGLIVAT SSSGNMGNLP
IILVPAICDE DKSPFGNRSV CRTVGLSYAS FSMALGGFYI WTYTFRLIKG SAMKLRDIEE
SEKATIKSSN SDLEADHKTQ LLLGASQDKK TSVVKEETGF WRKGVDLVHE ILEELLAPPT
LGAIVGFFFG AVKWLRNLII GDDAPLRIIQ GTAKLLGDGT IPCMTIILGG NLIQGLRSSA
VKPVVVLGIV CVRYIILPII GIGVVKTAES FGFLPQDPLF QYVLMLQFTL PPAMNIGTMT
QLYNVGQDEC SVLMLWTYLI AILALTVWST IFLHLLV
//
