ID V4MGS8_EUTSA Unreviewed; 913 AA.
AC V4MGS8;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE RecName: Full=RNA helicase {ECO:0000256|ARBA:ARBA00012552};
DE EC=3.6.4.13 {ECO:0000256|ARBA:ARBA00012552};
GN ORFNames=EUTSA_v10024349mg {ECO:0000313|EMBL:ESQ55769.1};
OS Eutrema salsugineum (Saltwater cress) (Sisymbrium salsugineum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Eutremeae; Eutrema.
OX NCBI_TaxID=72664 {ECO:0000313|EMBL:ESQ55769.1, ECO:0000313|Proteomes:UP000030689};
RN [1] {ECO:0000313|EMBL:ESQ55769.1, ECO:0000313|Proteomes:UP000030689}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23518688; DOI=10.3389/fpls.2013.00046;
RA Yang R., Jarvis D.E., Chen H., Beilstein M.A., Grimwood J., Jenkins J.,
RA Shu S., Prochnik S., Xin M., Ma C., Schmutz J., Wing R.A.,
RA Mitchell-Olds T., Schumaker K.S., Wang X.;
RT "The Reference Genome of the Halophytic Plant Eutrema salsugineum.";
RL Front. Plant Sci. 4:46-46(2013).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.13;
CC Evidence={ECO:0000256|ARBA:ARBA00001556};
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DR EMBL; KI517384; ESQ55769.1; -; Genomic_DNA.
DR RefSeq; XP_006414316.1; XM_006414253.1.
DR AlphaFoldDB; V4MGS8; -.
DR STRING; 72664.V4MGS8; -.
DR EnsemblPlants; ESQ55769; ESQ55769; EUTSA_v10024349mg.
DR GeneID; 18030764; -.
DR Gramene; ESQ55769; ESQ55769; EUTSA_v10024349mg.
DR KEGG; eus:EUTSA_v10024349mg; -.
DR eggNOG; KOG0923; Eukaryota.
DR OMA; MNDMEMH; -.
DR OrthoDB; 5488182at2759; -.
DR Proteomes; UP000030689; Unassembled WGS sequence.
DR GO; GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003724; F:RNA helicase activity; IEA:UniProtKB-EC.
DR GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR CDD; cd18791; SF2_C_RHA; 1.
DR Gene3D; 1.20.120.1080; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR011709; DEAD-box_helicase_OB_fold.
DR InterPro; IPR002464; DNA/RNA_helicase_DEAH_CS.
DR InterPro; IPR048333; HA2_WH.
DR InterPro; IPR007502; Helicase-assoc_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR18934; ATP-DEPENDENT RNA HELICASE; 1.
DR PANTHER; PTHR18934:SF222; PRE-MRNA-SPLICING FACTOR ATP-DEPENDENT RNA HELICASE DEAH8-RELATED; 1.
DR Pfam; PF13401; AAA_22; 1.
DR Pfam; PF21010; HA2_C; 1.
DR Pfam; PF04408; HA2_N; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF07717; OB_NTP_bind; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00847; HA2; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00690; DEAH_ATP_HELICASE; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW mRNA processing {ECO:0000256|ARBA:ARBA00022664};
KW mRNA splicing {ECO:0000256|ARBA:ARBA00023187};
KW Reference proteome {ECO:0000313|Proteomes:UP000030689};
KW Spliceosome {ECO:0000256|ARBA:ARBA00022728}.
FT DOMAIN 272..435
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 440..629
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 887..913
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 913 AA; 104535 MW; 544749A6FD7243E1 CRC64;
MESNDLKKTK TLEFAGEMHS TVQVRASVAN LDLYKHSEDN RDRFIADEKI PRGTVSVSFK
LNSSKKSIRK RSRESEEEDD DDKVLGNYEI ARLREVSRRE YLKNREKKKI EELRDEIEFE
LSRFDGVKLT EKEEIEFRYK RELYELLKKT EDDVGRYRIP VAYDQEGVID QKKRFAVATQ
RYGEGSSTRG MTEQEAWENH QAQKATVRFG AKNKKQASDG YEFVFDDLGG FVETSNEVET
EKHRDRDSRT VAEKDKEERN MLPIHAYRDE LLKLIEENQV LVIVGETGSG KTTQIPQYLR
EAGYTKRGKI GCTQPRRIAA MSVASRVAQE LGVKLGHEVG YSIRFEDCTS DKTVLKYMTD
GMLLRELLIE PKLDSYSVIM VDEAHERTLS TDILFGLVKD LANVRPDLRL IISSATLEAK
KFSEYFDSAR IYMIPGRRYP VEKFFNKLPE ADLLDTAIRT VFQIHETEPL GDILVFLTGQ
EEIEKAETKL KLRMIDLRTK SSEIIICPIY SNLPTELQAK VFEPAPKGSR KVVLATNIAE
TSITIDGIRY VVDPGYCKLN SYNPRTGMES LLVTPISKAS AEQRAGRSGR TGPGKCFRLY
NVKDLEATTV PEVQRANLAS VVLTLKSLGI EDVFNFDFMD PPPANALLKA LELLYALGAL
DGKGEITKLG ERMLEFPVDP MLSKMIVGSE RYKCSGEMIT IAAMLSTGNS IFYRPRQVRE
EYLADIARMN FYTENVGDHI ALLRVYNSWK ETNYSSQWCY ENYIQSKSMR RARDIRDQLA
GLLEKIGVEL TSNPNDLDAI KKAILAGFFP HSAKLQKDGS YRRVKEPQTV YVHPSSGLFT
ASPCKWLVYH ELVLTTKEYM RHITEMKPEW LIEIAPHYYE LKDIEEARPK KTQRSGRSPM
SKVGDTNKKV KRY
//
