ID V4Y383_9ARCH Unreviewed; 272 AA.
AC V4Y383;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 24-JAN-2024, entry version 24.
DE SubName: Full=Fructose-bisphosphate aldolase {ECO:0000313|EMBL:ESS07111.1};
DE EC=4.1.2.13 {ECO:0000313|EMBL:ESS07111.1};
GN ORFNames=A07HB70_00670 {ECO:0000313|EMBL:ESS07111.1};
OS uncultured archaeon A07HB70.
OC Archaea; environmental samples.
OX NCBI_TaxID=1412872 {ECO:0000313|EMBL:ESS07111.1, ECO:0000313|Proteomes:UP000030648};
RN [1] {ECO:0000313|Proteomes:UP000030648}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=24335829;
RA Podell S., Emerson J.B., Jones C.M., Ugalde J.A., Welch S.,
RA Heidelberg K.B., Banfield J.F., Allen E.E.;
RT "Seasonal fluctuations in ionic concentrations drive microbial succession
RT in a hypersaline lake community.";
RL ISME J. 0:0-0(2013).
CC -!- SIMILARITY: Belongs to the DeoC/FbaB aldolase family.
CC {ECO:0000256|ARBA:ARBA00008116}.
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DR EMBL; KI543174; ESS07111.1; -; Genomic_DNA.
DR AlphaFoldDB; V4Y383; -.
DR STRING; 1412872.A07HB70_00670; -.
DR PATRIC; fig|1412872.3.peg.687; -.
DR Proteomes; UP000030648; Unassembled WGS sequence.
DR GO; GO:0004332; F:fructose-bisphosphate aldolase activity; IEA:UniProtKB-EC.
DR CDD; cd00958; DhnA; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR002915; DeoC/FbaB/LacD_aldolase.
DR InterPro; IPR041720; FbaB-like.
DR PANTHER; PTHR47916:SF1; 3-HYDROXY-5-PHOSPHONOOXYPENTANE-2,4-DIONE THIOLASE-RELATED; 1.
DR PANTHER; PTHR47916; FRUCTOSE-BISPHOSPHATE ALDOLASE CLASS 1; 1.
DR Pfam; PF01791; DeoC; 1.
DR PIRSF; PIRSF038992; Aldolase_Ia; 1.
DR SMART; SM01133; DeoC; 1.
DR SUPFAM; SSF51569; Aldolase; 1.
PE 3: Inferred from homology;
KW Lyase {ECO:0000313|EMBL:ESS07111.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000030648}.
FT ACT_SITE 146
FT /note="Proton donor"
FT /evidence="ECO:0000256|PIRSR:PIRSR038992-1"
FT ACT_SITE 177
FT /note="Schiff-base intermediate with dihydroxyacetone-P"
FT /evidence="ECO:0000256|PIRSR:PIRSR038992-1"
SQ SEQUENCE 272 AA; 29157 MW; E336117BEA0D0788 CRC64;
MRKGADGSIT RDGRMLILAY DHGLEHGPVD FEPVPETADP EVVFDLATHD AVTALAVQKG
IAEAYYPDYA DDVTLLAKLN GTSNMWSGEP DSAVNWSVDY AAEVGADAIG FTVYGGSNHE
IEMVEEFREA QERAREHGMA VVMWAYPRGQ GLRNAESPDT IAYSARTALE LGADVAKVKH
PGSREAMAHA VEVSGRTKVV MSGGSKTDDL QFLRTVESAI AAGAKGLAVG RNVFQREHPR
AILDALEAVI FDGESAEDAL ELATRGPERA AD
//
