ID V4Y6B9_9ARCH Unreviewed; 578 AA.
AC V4Y6B9;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 24-JAN-2024, entry version 37.
DE SubName: Full=Mismatch repair ATPase (MutS family) {ECO:0000313|EMBL:ESS08261.1};
DE Flags: Fragment;
GN ORFNames=A07HN63_02283 {ECO:0000313|EMBL:ESS08261.1};
OS uncultured archaeon A07HN63.
OC Archaea; environmental samples.
OX NCBI_TaxID=1412873 {ECO:0000313|EMBL:ESS08261.1, ECO:0000313|Proteomes:UP000030667};
RN [1] {ECO:0000313|Proteomes:UP000030667}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=24335829;
RA Podell S., Emerson J.B., Jones C.M., Ugalde J.A., Welch S.,
RA Heidelberg K.B., Banfield J.F., Allen E.E.;
RT "Seasonal fluctuations in ionic concentrations drive microbial succession
RT in a hypersaline lake community.";
RL ISME J. 0:0-0(2013).
CC -!- SIMILARITY: Belongs to the DNA mismatch repair MutS family.
CC {ECO:0000256|ARBA:ARBA00006271}.
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DR EMBL; KI543219; ESS08261.1; -; Genomic_DNA.
DR AlphaFoldDB; V4Y6B9; -.
DR STRING; 1412873.A07HN63_02283; -.
DR PATRIC; fig|1412873.3.peg.2407; -.
DR Proteomes; UP000030667; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR GO; GO:0030983; F:mismatched DNA binding; IEA:InterPro.
DR GO; GO:0006298; P:mismatch repair; IEA:InterPro.
DR CDD; cd03284; ABC_MutS1; 1.
DR Gene3D; 1.10.1420.10; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR011184; DNA_mismatch_repair_Msh2.
DR InterPro; IPR000432; DNA_mismatch_repair_MutS_C.
DR InterPro; IPR007861; DNA_mismatch_repair_MutS_clamp.
DR InterPro; IPR007696; DNA_mismatch_repair_MutS_core.
DR InterPro; IPR036187; DNA_mismatch_repair_MutS_sf.
DR InterPro; IPR045076; MutS_family.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR11361:SF34; DNA MISMATCH REPAIR PROTEIN MSH1, MITOCHONDRIAL; 1.
DR PANTHER; PTHR11361; DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER; 1.
DR Pfam; PF05192; MutS_III; 1.
DR Pfam; PF05190; MutS_IV; 1.
DR Pfam; PF00488; MutS_V; 1.
DR PIRSF; PIRSF005813; MSH2; 1.
DR SMART; SM00534; MUTSac; 1.
DR SMART; SM00533; MUTSd; 1.
DR SUPFAM; SSF48334; DNA repair protein MutS, domain III; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00486; DNA_MISMATCH_REPAIR_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA damage {ECO:0000256|ARBA:ARBA00023204};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT DOMAIN 356..372
FT /note="DNA mismatch repair proteins mutS family"
FT /evidence="ECO:0000259|PROSITE:PS00486"
FT REGION 464..528
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ESS08261.1"
SQ SEQUENCE 578 AA; 62193 MW; 91152154A228AB35 CRC64;
GIARSDLHDR LGEAYDLERL AGRVSRERAT ARDLRALHTT LSIVPDLKEL IADIPALSDH
HDRLDELRDV ATLIDEAITT DPPMELTEGG VIKQSFDDEL DTLRTTEQNG REWVADLEAA
ERERTGIDSL SVGHNQVHGY YIEVTNPNLD QVPDDYTRRQ TLKNAERFYT PELKEREDEI
FGAAERADSL EYELFCDVRE TVAAETDRIQ ALATVIAELD ALCSLAITAT ERDYVRPDLQ
PAGSDPQIEI HGGRHPVVET TQQEFVPNDT DLDSGGVAII TGPNMSGKST YMRQVALLCL
LAQTGSFVPA DAATLPILDR IFTRVGASDD IAGGESTFMR EMSELTEILH DATENSLVLL
DEVGRGTSTA DGLAIAQATT EFIHDELDAL TLFATHYHGL TGLADEREGV HNLHFAATRE
DDDVTFLHRV APGASSASYG IEVARMAGVP TAVVDRAREV VATTTGEDKT VTGDNEAAES
SDEGDRTDEL TDDTSTESAA TNGASPADGP ADGDGVSSGE SDTTVAGEAV ADALDGDSLD
AEAVATVASD LRDLDIATMT PLEALTTLDE LRSTLADE
//
