ID V4Z4K1_TOXGV Unreviewed; 2343 AA.
AC V4Z4K1; A0A0F7VA03;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 24-JAN-2024, entry version 35.
DE RecName: Full=Prolyl endopeptidase-like {ECO:0000256|ARBA:ARBA00039290};
DE AltName: Full=Prolylendopeptidase-like {ECO:0000256|ARBA:ARBA00042165};
GN ORFNames=BN1205_070460 {ECO:0000313|EMBL:CEL78099.1}, TGVEG_219485
GN {ECO:0000313|EMBL:ESS28916.1};
OS Toxoplasma gondii (strain ATCC 50861 / VEG).
OC Eukaryota; Sar; Alveolata; Apicomplexa; Conoidasida; Coccidia;
OC Eucoccidiorida; Eimeriorina; Sarcocystidae; Toxoplasma.
OX NCBI_TaxID=432359 {ECO:0000313|EMBL:ESS28916.1, ECO:0000313|Proteomes:UP000002226};
RN [1] {ECO:0000313|EMBL:ESS28916.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=VEG {ECO:0000313|EMBL:ESS28916.1};
RA Paulsen I.;
RL Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000002226}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 50861 / VEG {ECO:0000313|Proteomes:UP000002226};
RA Lorenzi H., Inman J., Amedeo P., Brunk B., Roos D., Caler E.;
RT "Annotation of Toxoplasma gondii VEG.";
RL Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:ESS28916.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=VEG {ECO:0000313|EMBL:ESS28916.1};
RA Sibley D., Venepally P., Karamycheva S., Hadjithomas M., Khan A., Brunk B.,
RA Roos D., Caler E., Lorenzi H.;
RL Submitted (AUG-2013) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|EMBL:CEL78099.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=VEG {ECO:0000313|EMBL:CEL78099.1};
RX PubMed=25875305; DOI=10.1371/journal.pone.0124473;
RA Ramaprasad A., Mourier T., Naeem R., Malas T.B., Moussa E., Panigrahi A.,
RA Vermont S.J., Otto T.D., Wastling J., Pain A.;
RT "Comprehensive Evaluation of Toxoplasma gondii VEG and Neospora caninum LIV
RT Genomes with Tachyzoite Stage Transcriptome and Proteome Defines Novel
RT Transcript Features.";
RL PLoS ONE 10:e0124473-e0124473(2015).
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DR EMBL; LN714502; CEL78099.1; -; Genomic_DNA.
DR EMBL; AAYL02000326; ESS28916.1; -; Genomic_DNA.
DR STRING; 432359.V4Z4K1; -.
DR PaxDb; 5811-TGME49_019480; -.
DR EnsemblProtists; ESS28916; ESS28916; TGVEG_219485.
DR VEuPathDB; ToxoDB:TGVEG_219485; -.
DR eggNOG; KOG2237; Eukaryota.
DR OMA; IVKPWHS; -.
DR Proteomes; UP000002226; Partially assembled WGS sequence.
DR GO; GO:0008236; F:serine-type peptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR001375; Peptidase_S9.
DR PANTHER; PTHR11757:SF19; PROLYL ENDOPEPTIDASE-LIKE; 1.
DR PANTHER; PTHR11757; PROTEASE FAMILY S9A OLIGOPEPTIDASE; 1.
DR Pfam; PF00326; Peptidase_S9; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000002226}.
FT DOMAIN 1783..1886
FT /note="Peptidase S9 prolyl oligopeptidase catalytic"
FT /evidence="ECO:0000259|Pfam:PF00326"
FT REGION 1..26
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 89..164
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 340..368
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 444..484
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 544..630
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 642..701
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 743..773
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1127..1169
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1255..1275
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1518..1590
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1626..1655
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1699..1724
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1887..1961
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2008..2122
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2169..2223
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2235..2267
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 124..164
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 444..469
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 470..484
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 544..586
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 595..630
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 645..671
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 683..701
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 746..773
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1133..1169
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1520..1562
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1573..1587
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1627..1653
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1889..1961
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2027..2052
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2059..2122
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2173..2209
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2343 AA; 256225 MW; 8789B64CB44A6E42 CRC64;
MGKPVHLRPL APAVLSRRPP AADPHEGGCA VQAFLSCARR FHRNARSRSS DAPLSFAPRP
IDRVLESRLS FASTQTCVVS RCRDGSLLCG RGEAGGERKQ GGTVQRGRPN ADGGGPSSGE
RLPTEEKGGG ETEAATARDK KARVSGRPLV GLREKSDTSA RQKHTVCDRE TLLREMDTHA
GDHKPLSFDL PKDAFPSQGD LLVSGTDPWR ALEDDAAILH TFFPSARRSA IARRQREWRS
QETNEERTLE NGDLDFPSES AVFVSERGCD FSPVCSLEKK TRRPPRERER GRDVERLYHS
QDLLTPPLRQ YLTFANKECI SAIDFAEEAL NSLVVASPRN ENLDRTPSSS KSSSSCVSSS
VDSSSISSTC AASLPSDARR TDCGGASTDS PSHLFPAEEE LFYTSRFLDR FCGKAVAETA
KEQAVAELLS WMYRQKVCRS SAVAASEPTS RGRHSSDALQ ASRGTGNEQS KQVEGERRRG
EREDEEISVC KEAVWRQVEA AAQAAEVADS LSVEVLDGRW VYYERPSPFD PGYPVICRRR
LPGKRETETH RERVLPSDRG SGENARSPSE ETRFQERAKR RKVSSDACPD NTAVKKERIS
STPLNRREAS SPPFSFPSSP SSFPSSASPF SLDSPFLQHS FSATSGREED GRGDIDARAR
KQREAAEERS SEEAPPLLTL ADVIQRERDE RRRQRETREE RDPKLENLFL SRVLEPPGLW
TALDVLRGEE QLLDVGWLTT GDAGEERQDS CSDRSTRVSR VSDAEKSPEE RQEAARVSDC
RVGALKAFDE AAILGYTRCL DSSERYTLHF KDLLSGSRFP ASFCGSSTRP CVSSRVTAQA
SALNGQTENE RSPCVRRNRP SACSWDCQEL PGVSLGFVKD FEFFAVGEPS PGSERWHNCT
REVTELATER DQQGSGVLGA AKQPRVLGCM YTSVDPWTGR PHMLRRCLLA LHRPSDSVFP
SFFSPLSLAS LRSSGIARKH ARNAEARNST PHLEVLRDEI VLDLSDETLW GAMHVALGKT
PDGRFFTITA TSRCRTASWI LSATNALDTP LPVMDGPTHF FTTRGKHLLL FDVSQHNAFS
AFALSLEAVL ERQGVQKVGE NSFRFPLSSF ESSAPVFPGD ASRRAISPGM RYPSSEPMTN
NLNAETSFAP SLSESSSAPP DSSSLSSSLS SSSLPPFRSS SLSSSPSPSA LSPLDSVEAG
AVGTLRLIRL FHLSSFLFSD LDLTPRHIAV YGLRSPSCPV VVVVELADSE TDQHSLSSSL
SDLPNSSSSS DASASPPSPP FLFLSSSSSS LSSSSLPSSS LSPSPDASLS SLSTSPALLS
CSSVSPVSSR ETSAAQASPS WKSQVTEVRL SALSNSSGVG VLQPGVNHHT SFLRFLLQSP
FEPSLQCSLD LRTMSVRTQR LHTVDLEILK TAAKVFLLRF FPSLSFTPFL LRDTENTVLS
SRSSFSSSLC HSNSSSSTSS SCSPLSPVPA SPFASSSSSS SSSSSSLSSS SLSSSSCFTA
PHLSSAASDF FAAGRPRPLS LGERRSEPEE APGSEVTSSE RAESRKERED AEKPRRVEEL
RTVSLANFEG AEPPCGDRED DGEHGSFESN PLGKVEVISL PSRDGKSLIP VTLLLPANFE
AEARGATLAS QDKRERKECE GTAQEKLQEP TEKECANPEN LALMKKTTED QDRPVFMFTI
SVHPFSSRFS HLCSSSTTSS TSSTSSTSSS SSLSSPVSSL SSSSASCMSD VRSHTDKTFR
SCSQRSHGTD EAFSFRCWGA SPLLLLAYGA YKRPLAVAFS PLHLLLLSLG WRVAFVHCRG
EGAGECEGGE SGRGLRKHES LDDLEDAVDA FVAMNLAERN SIFLKTSSAG GVLAGAFLAF
QKLRTRIRGV VIRHGFFDVY TAMRKGSGEA REGGGEELRG EDQENSRKGR EARMGKGKEE
ALREEKGESS RGEEDPLRRL EEAEWGNPNC RGEDETDVER EERNAHLGNI LSYSPYTNFH
PPRGYLLRLA KAKPVFPRGR SRDCFALSSK PAARSAKGGD LVEAQGGFHS ENSTERRTGR
WSGSNNGVDS VGQQRGKRLG NGQEERPKEV RSSREDALEP SFQEREEEMG VEFFGRDSTG
ERRKDLCFPP RGKSCGEHPT RVRDSDWEFP SLFLSTSLGD GIVKPWHSAK FLGKLETMRS
LGEKGVFSVP RNATESDRHK ELLGEANESR HAERQLSSSR KRQDEGEARG QQAARAAAGA
HATSIWRAQE THRLERKSHA VRHTHMPVGD GNSRPGKQSL SEHHASGRIL ERNPFRESHT
ADEVDACVSE RDPGEHLILF KLKGDAEGHC GSENRMAQYR DEAEELCFFY RVLQNGEDKE
SRE
//
