ID V5B4V8_TRYCR Unreviewed; 832 AA.
AC V5B4V8;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Trans-sialidase {ECO:0000313|EMBL:ESS62619.1};
GN ORFNames=TCDM_09703 {ECO:0000313|EMBL:ESS62619.1};
OS Trypanosoma cruzi Dm28c.
OC Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC Trypanosomatida; Trypanosomatidae; Trypanosoma; Schizotrypanum.
OX NCBI_TaxID=1416333 {ECO:0000313|EMBL:ESS62619.1, ECO:0000313|Proteomes:UP000017861};
RN [1] {ECO:0000313|EMBL:ESS62619.1, ECO:0000313|Proteomes:UP000017861}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Dm28c {ECO:0000313|EMBL:ESS62619.1,
RC ECO:0000313|Proteomes:UP000017861};
RX PubMed=24482508;
RA Grisard E.C., Teixeira S.M., de Almeida L.G., Stoco P.H., Gerber A.L.,
RA Talavera-Lopez C., Lima O.C., Andersson B., de Vasconcelos A.T.;
RT "Trypanosoma cruzi Clone Dm28c Draft Genome Sequence.";
RL Genome Announc. 2:e01114-13(2014).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ESS62619.1}.
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DR EMBL; AYLP01000172; ESS62619.1; -; Genomic_DNA.
DR AlphaFoldDB; V5B4V8; -.
DR EnsemblProtists; ESS62619; ESS62619; TCDM_09703.
DR VEuPathDB; TriTrypDB:TCDM_09703; -.
DR Proteomes; UP000017861; Unassembled WGS sequence.
DR GO; GO:0004308; F:exo-alpha-sialidase activity; IEA:InterPro.
DR CDD; cd15482; Sialidase_non-viral; 1.
DR Gene3D; 2.120.10.10; -; 1.
DR Gene3D; 2.60.120.200; -; 1.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR011040; Sialidase.
DR InterPro; IPR026856; Sialidase_fam.
DR InterPro; IPR036278; Sialidase_sf.
DR InterPro; IPR008377; Sialidase_trypan.
DR InterPro; IPR021287; Trans-sialidase_CS.
DR PANTHER; PTHR10628; SIALIDASE; 1.
DR PANTHER; PTHR10628:SF25; SIALIDASE-1; 1.
DR Pfam; PF13859; BNR_3; 1.
DR Pfam; PF13385; Laminin_G_3; 1.
DR Pfam; PF11052; Tr-sialidase_C; 1.
DR PRINTS; PR01803; TCSIALIDASE.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR SUPFAM; SSF50939; Sialidases; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000017861};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..27
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 28..832
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004731317"
FT DOMAIN 53..391
FT /note="Sialidase"
FT /evidence="ECO:0000259|Pfam:PF13859"
FT REGION 669..699
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 727..776
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 682..699
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 832 AA; 88419 MW; CB74218CC7ECDCDC CRC64;
MSRRVYTSTV LLLLVVMVCC GSGGASAEVK PSSDPKFQWK DITDGVTVDS LGVPGLLKVG
SDVFAVAEAQ CKKDGKCFTG IASQLLTMGK GKEPEEVLKE AKDTQILEEG GSTEEEKKVD
VSRPTTVVDE SDIYMLVGKH SHDDLAKCKA ATDRIKSGIL LVKGKVGEDG KKIDWKETDG
VPCTLGEKHE SFSQLIVGGG SGVKMKDGTF LFPVEATKKE EEKTVSLIMY SSKEVTNWKL
SKGMSADGCS DPSVVEWKDD KLMMMTACDD GRRRVYESGD KGESWTEALG TLSRVWGNEQ
KGKVEIVRSG FVTAALGDNE GNNRNVMLVT LPVYSKEKDN SKGVLHLWLT DNTHIVDIGS
VSGDDVDAAA SSLLYKSGER GDNNELIALY EKKKGAGETP SPGMVSVLLT EQLKLVKDVL
TTWNDVDERV SKLCPLSNAA VSKSTDTACT TFKITAGLVG FLSGNFSGTT WKDEYLGVNA
TVNNKAAAGK TDNGVKFTGR GAWTEWPVGR QGENQLYHFA NYNFTLVATV SIHKVPKEGS
IPLMGAKMND SENTVLLGLS YNKEKNWILL CDGGENKEQS RVSEPEKAQH VVILLRNGSQ
GSAYVDGQPV GGDEQCELKT KASKEISHFY IGGDGGSAEG QEGVSVTVSN VLLYNRPLSS
EEIDALNPNK VTIPKPEGPK TLVVDTQSSA TSGSPVQGAV SLSNSARQLP LEQELLKENI
GGGAGGVSGA ASVTTPSADA KTPASNGEGK VEPAVKKEMS VNSGEDEDTA DGTDAQGEEG
IHLQVREVNA TALSSSLGNV SQENNSDGGT MSESGLLPSL LLLLGLWGFA AL
//
