ID V5BM67_TRYCR Unreviewed; 359 AA.
AC V5BM67;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=SET domain-containing protein {ECO:0000259|PROSITE:PS50280};
GN ORFNames=TCDM_05973 {ECO:0000313|EMBL:ESS65588.1};
OS Trypanosoma cruzi Dm28c.
OC Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC Trypanosomatida; Trypanosomatidae; Trypanosoma; Schizotrypanum.
OX NCBI_TaxID=1416333 {ECO:0000313|EMBL:ESS65588.1, ECO:0000313|Proteomes:UP000017861};
RN [1] {ECO:0000313|EMBL:ESS65588.1, ECO:0000313|Proteomes:UP000017861}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Dm28c {ECO:0000313|EMBL:ESS65588.1,
RC ECO:0000313|Proteomes:UP000017861};
RX PubMed=24482508;
RA Grisard E.C., Teixeira S.M., de Almeida L.G., Stoco P.H., Gerber A.L.,
RA Talavera-Lopez C., Lima O.C., Andersson B., de Vasconcelos A.T.;
RT "Trypanosoma cruzi Clone Dm28c Draft Genome Sequence.";
RL Genome Announc. 2:e01114-13(2014).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ESS65588.1}.
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DR EMBL; AYLP01000061; ESS65588.1; -; Genomic_DNA.
DR AlphaFoldDB; V5BM67; -.
DR EnsemblProtists; ESS65588; ESS65588; TCDM_05973.
DR VEuPathDB; TriTrypDB:TCDM_05973; -.
DR Proteomes; UP000017861; Unassembled WGS sequence.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR CDD; cd20071; SET_SMYD; 1.
DR Gene3D; 2.170.270.10; SET domain; 1.
DR InterPro; IPR001214; SET_dom.
DR InterPro; IPR046341; SET_dom_sf.
DR PANTHER; PTHR46402:SF2; HISTONE-LYSINE N-TRIMETHYLTRANSFERASE SMYD5; 1.
DR PANTHER; PTHR46402; SET AND MYND DOMAIN-CONTAINING PROTEIN 5; 1.
DR Pfam; PF00856; SET; 1.
DR SUPFAM; SSF82199; SET domain; 1.
DR PROSITE; PS50280; SET; 1.
PE 4: Predicted;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603};
KW Reference proteome {ECO:0000313|Proteomes:UP000017861};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 187..306
FT /note="SET"
FT /evidence="ECO:0000259|PROSITE:PS50280"
SQ SEQUENCE 359 AA; 41616 MW; 2BCC9020DD2C50DD CRC64;
MKLPYAKLEK HSRPVRCVHA EYGCTMLFCS VRCRQAGWSR FHFAGCPGAM MSDQRDAYDE
FIHHDWEYRG VDYSDTVFLA FRFVCMAVTN IRLHRQSLEL AYRPIAQLIK APLSFFHFTY
LFYKEEADST EKKGRGEKQV EKLRLIRWEA FRKFRATHMS TTENDTTDEF LATGMTLLGR
ILRFTQEECT LFTVARWSEL LGAVLLNGQE RSPPSNYDRL KELVQRLPCG ESTMDAFEQE
VQMAGKELQH LLQSSRGQGV YTVGCLFNHS CEPNLQVVYS ESGDETLSVV ALRNIELGEE
LCISYIDESL SYPERQQELY EHYLFVCQCP KCEREAAAWE PIEPCKEALS SAYTFSQLY
//
