ID V5BMU1_TRYCR Unreviewed; 404 AA.
AC V5BMU1;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 22-FEB-2023, entry version 21.
DE SubName: Full=DNA topoisomerase III {ECO:0000313|EMBL:ESS69104.1};
GN ORFNames=TCDM_02132 {ECO:0000313|EMBL:ESS69104.1};
OS Trypanosoma cruzi Dm28c.
OC Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC Trypanosomatida; Trypanosomatidae; Trypanosoma; Schizotrypanum.
OX NCBI_TaxID=1416333 {ECO:0000313|EMBL:ESS69104.1, ECO:0000313|Proteomes:UP000017861};
RN [1] {ECO:0000313|EMBL:ESS69104.1, ECO:0000313|Proteomes:UP000017861}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Dm28c {ECO:0000313|EMBL:ESS69104.1,
RC ECO:0000313|Proteomes:UP000017861};
RX PubMed=24482508;
RA Grisard E.C., Teixeira S.M., de Almeida L.G., Stoco P.H., Gerber A.L.,
RA Talavera-Lopez C., Lima O.C., Andersson B., de Vasconcelos A.T.;
RT "Trypanosoma cruzi Clone Dm28c Draft Genome Sequence.";
RL Genome Announc. 2:e01114-13(2014).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ESS69104.1}.
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DR EMBL; AYLP01000014; ESS69104.1; -; Genomic_DNA.
DR AlphaFoldDB; V5BMU1; -.
DR EnsemblProtists; ESS69104; ESS69104; TCDM_02132.
DR VEuPathDB; TriTrypDB:TCDM_02132; -.
DR Proteomes; UP000017861; Unassembled WGS sequence.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR GO; GO:0016853; F:isomerase activity; IEA:UniProtKB-KW.
DR Gene3D; 1.20.900.10; Dbl homology (DH) domain; 1.
DR InterPro; IPR035899; DBL_dom_sf.
DR InterPro; IPR000219; DH-domain.
DR SUPFAM; SSF48065; DBL homology domain (DH-domain); 1.
DR PROSITE; PS50010; DH_2; 1.
PE 4: Predicted;
KW Isomerase {ECO:0000313|EMBL:ESS69104.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000017861}.
FT DOMAIN 8..254
FT /note="DH"
FT /evidence="ECO:0000259|PROSITE:PS50010"
SQ SEQUENCE 404 AA; 45518 MW; 2EF23C8EEF8821ED CRC64;
MPRDGVLEEM QVYDEFALSE MLYVACLETL LSAYIVPLSN TLCLTTSDGN LSSSHCGDHS
DLLRTFGDDV LQLLSCHRAI INGLRIFTEG CGESDSNGNF EGHERSYLAN RATRVLRRGV
PAMRAAYQRY VMNFNENARR ALLAKSSVPQ DVWRSGYGAL AQDILTNSLL HLGVEKRDII
RFSEGCNLSL EALSLLPMQH IARYPLYMDG FIQIQRHVAS VNISNTNDDD AARIAKAEET
LAALIDICST VNATRASVIE FQRMVELQKS LELTEISSKL LSEGDVVVSF ELQEEKTKLQ
GRCSHGRLIL LSDTLFVQLH EKKRARCEKH LERIPLKSIM SVRFSNQASE GAVYITYNPD
TERRKWRVKK QRKKCVVLFL PNEAEALIWA SDITRAVSDL TPEE
//
