ID V5C5J3_9GAMM Unreviewed; 707 AA.
AC V5C5J3;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 24-JAN-2024, entry version 40.
DE SubName: Full=Molybdopterin oxidoreductase Fe4S4 {ECO:0000313|EMBL:ESS71998.1};
GN ORFNames=MGMO_77c00110 {ECO:0000313|EMBL:ESS71998.1};
OS Methyloglobulus morosus KoM1.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Methylococcales;
OC Methylococcaceae; Methyloglobulus.
OX NCBI_TaxID=1116472 {ECO:0000313|EMBL:ESS71998.1, ECO:0000313|Proteomes:UP000017842};
RN [1] {ECO:0000313|EMBL:ESS71998.1, ECO:0000313|Proteomes:UP000017842}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KoM1 {ECO:0000313|EMBL:ESS71998.1,
RC ECO:0000313|Proteomes:UP000017842};
RX PubMed=24356841;
RA Poehlein A., Deutzmann J.S., Daniel R., Simeonova D.D.;
RT "Draft Genome Sequence of the Methanotrophic Gammaproteobacterium
RT Methyloglobulus morosus DSM 22980 Strain KoM1.";
RL Genome Announc. 1:e01078-13(2013).
CC -!- COFACTOR:
CC Name=Mo-bis(molybdopterin guanine dinucleotide);
CC Xref=ChEBI:CHEBI:60539; Evidence={ECO:0000256|ARBA:ARBA00001942};
CC -!- SIMILARITY: Belongs to the prokaryotic molybdopterin-containing
CC oxidoreductase family. {ECO:0000256|ARBA:ARBA00010312}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ESS71998.1}.
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DR EMBL; AYLO01000074; ESS71998.1; -; Genomic_DNA.
DR RefSeq; WP_023494929.1; NZ_AYLO01000074.1.
DR AlphaFoldDB; V5C5J3; -.
DR STRING; 1116472.MGMO_77c00110; -.
DR PATRIC; fig|1116472.3.peg.2191; -.
DR eggNOG; COG0243; Bacteria.
DR OrthoDB; 9810782at2; -.
DR Proteomes; UP000017842; Unassembled WGS sequence.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0043546; F:molybdopterin cofactor binding; IEA:InterPro.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR CDD; cd02766; MopB_3; 1.
DR CDD; cd02786; MopB_CT_3; 1.
DR Gene3D; 2.40.40.20; -; 1.
DR Gene3D; 3.40.50.740; -; 1.
DR Gene3D; 2.20.25.90; ADC-like domains; 1.
DR Gene3D; 3.40.228.10; Dimethylsulfoxide Reductase, domain 2; 1.
DR Gene3D; 3.30.2070.10; Formate dehydrogenase/DMSO reductase; 1.
DR InterPro; IPR009010; Asp_de-COase-like_dom_sf.
DR InterPro; IPR006657; MoPterin_dinucl-bd_dom.
DR InterPro; IPR006656; Mopterin_OxRdtase.
DR InterPro; IPR006963; Mopterin_OxRdtase_4Fe-4S_dom.
DR InterPro; IPR006655; Mopterin_OxRdtase_prok_CS.
DR InterPro; IPR037920; YoaE_C.
DR PANTHER; PTHR43742:SF6; OXIDOREDUCTASE YYAE-RELATED; 1.
DR PANTHER; PTHR43742; TRIMETHYLAMINE-N-OXIDE REDUCTASE; 1.
DR Pfam; PF04879; Molybdop_Fe4S4; 1.
DR Pfam; PF00384; Molybdopterin; 1.
DR Pfam; PF01568; Molydop_binding; 1.
DR SMART; SM00926; Molybdop_Fe4S4; 1.
DR SUPFAM; SSF50692; ADC-like; 1.
DR SUPFAM; SSF53706; Formate dehydrogenase/DMSO reductase, domains 1-3; 1.
DR PROSITE; PS51669; 4FE4S_MOW_BIS_MGD; 1.
DR PROSITE; PS00932; MOLYBDOPTERIN_PROK_3; 1.
PE 3: Inferred from homology;
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000017842}.
FT DOMAIN 6..63
FT /note="4Fe-4S Mo/W bis-MGD-type"
FT /evidence="ECO:0000259|PROSITE:PS51669"
SQ SEQUENCE 707 AA; 77984 MW; A5C91181F0C60B9E CRC64;
MVETIKTMHH GGCPHDCPDT CSMVFEVKDG KLAGVKGNPD HPMTRGGLCV KLKDYEKRHY
HPDRLLYPMR RTGPKGSKQF ERISWDEALD EITTRWKTII AGHGPQAILP YSYLGNQGLV
HGLNGGDAFF NRMGATVTER TFCGEGSSTA WLLTVGPTAG VDPESFIHSK YIIIWACNSV
STNLHHWHIV KEAQKKGAKV VVIDTYASKT AKEADWHIAP KPGTDGALAM AMIHTIIEEG
LLDQDYVDHY TIGFAELKDR ASLRTPEWAE AVTGIPAVVI RTLAREYAMT QPAAIRMGVA
LERHKGGGQT IRAVSCLPAL TGAWRHVGGG ALQFPVWEHP YRFDVICRPD LIPEGTRVVN
ALQIGRALTD EPPAGPPIKS MMCWNANPVT QAPETDKIVN GLMNEHLFLV SAEHFISDTA
LYADILLPAS MGAEMEDMIL SWGHLYLTYN AKCVNSPGEA IPNNEIFRRL AQRMGYEEDN
FKWSDSECLE QYVDWNSPAC EGIDLDYLRK HGFARLNVGT KDNRAPHKNG NFPTPSGKCQ
FKAKGAVNFV PGPFRQMYDG FQPGEVLDPL PDYVPSRESA STNPDLALKY PLSIVSPKSH
GFLNSCYANM DNKIQGQGEQ FVLINAIDAN NRGIKNGDKV RVYNDRGCFE GNAKITDDVN
PGLIIATLGY WRQLNKGTVN SISSAELVNM GNAPSFSDNL VQLESAC
//
