ID V5ELJ5_9LACO Unreviewed; 1704 AA.
AC V5ELJ5;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 24-JAN-2024, entry version 46.
DE SubName: Full=Mucus-binding protein {ECO:0000313|EMBL:EST02729.1};
GN ORFNames=Lc367_0296 {ECO:0000313|EMBL:EST02729.1};
OS Lactobacillus crispatus EM-LC1.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC Lactobacillus.
OX NCBI_TaxID=1328863 {ECO:0000313|EMBL:EST02729.1, ECO:0000313|Proteomes:UP000017999};
RN [1] {ECO:0000313|EMBL:EST02729.1, ECO:0000313|Proteomes:UP000017999}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=EM-LC1 {ECO:0000313|EMBL:EST02729.1,
RC ECO:0000313|Proteomes:UP000017999};
RX PubMed=24356836;
RA Power S.E., Harris H.M., Bottacini F., Ross R.P., O'Toole P.W.,
RA Fitzgerald G.F.;
RT "Draft Genome Sequence of Lactobacillus crispatus EM-LC1, an Isolate with
RT Antimicrobial Activity Cultured from an Elderly Subject.";
RL Genome Announc. 1:e01070-13(2013).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EST02729.1}.
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DR EMBL; AXLM01000062; EST02729.1; -; Genomic_DNA.
DR RefSeq; WP_023488860.1; NZ_AXLM01000062.1.
DR PATRIC; fig|1328863.3.peg.1805; -.
DR Proteomes; UP000017999; Unassembled WGS sequence.
DR Gene3D; 2.60.40.4300; -; 3.
DR Gene3D; 3.10.20.470; -; 1.
DR InterPro; IPR019931; LPXTG_anchor.
DR InterPro; IPR041495; Mub_B2.
DR InterPro; IPR041558; MucBP_2.
DR InterPro; IPR005877; YSIRK_signal_dom.
DR NCBIfam; TIGR01167; LPXTG_anchor; 1.
DR NCBIfam; TIGR01168; YSIRK_signal; 1.
DR Pfam; PF00746; Gram_pos_anchor; 1.
DR Pfam; PF17966; Muc_B2; 3.
DR Pfam; PF17965; MucBP_2; 1.
DR Pfam; PF04650; YSIRK_signal; 1.
DR PROSITE; PS50847; GRAM_POS_ANCHORING; 1.
PE 4: Predicted;
KW Cell wall {ECO:0000256|ARBA:ARBA00022512};
KW Peptidoglycan-anchor {ECO:0000256|ARBA:ARBA00023088};
KW Secreted {ECO:0000256|ARBA:ARBA00022512};
KW Signal {ECO:0000256|ARBA:ARBA00022729}.
FT DOMAIN 1670..1704
FT /note="Gram-positive cocci surface proteins LPxTG"
FT /evidence="ECO:0000259|PROSITE:PS50847"
FT REGION 39..113
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1538..1675
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 39..62
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 70..88
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1538..1559
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1560..1574
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1584..1604
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1605..1662
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1704 AA; 185409 MW; 760D432B4C26AA9B CRC64;
MRERKNHYSI RKLTIGVASV LIGISFFGIK ADTVQAETSN SNESISQESE QTNANTSESA
QDEPSATRER QNADSPSNST TSNVQEDRTD PAANRDKIGK EAPSASATFG KNSTLTIDHG
QLDEKQKTAK LTMNSADFQA GDTYTITIPK KGGLSLGKTD VAVLAPVFGK TTFTETIDYY
KIEDHFINGG TITQNINLHY DKNINPLASM TNTITVDTTG SAEKHASLKV IAIGKEPELS
ADLVHVPQPI INGQEFTTRP ALTLGTPLKD FNQVDLNLAL DKNYKLTNIT LNDEDQSLVL
TPDQLTIDAN NVAHIVLNEE QITSLLKGQS NHFNFKITGH FDIPASDFVN KKYHAKFLDK
DKSTISGTMV NVTTKPSHIG TITGTGVDDL TIYPTVKDID WAATVNYLTE YTAHDKDNPG
KDTSGVMVVD GKTSSTTDMH YFTLSNQSTL DITDANLTVD LPDGYNVPAT LTLSENTIYQ
DQDQDPDNIN FIVSYVDGTS AVITPDQFGN TLTFHVTPNK KIRSLNVRIA QWNPDVEYDL
SSKHGTYSKT YANGQPVLVG DLLTTKTTLS SPSFNGEVMM PMTTVIDRLV NKVKEGTFTA
VYPFLPNQTS TVPGEKNAGS LTYETCVSGY GHPMLKHPIT YIMVPDNAEV ADLSKVTVKY
SGAYVDYQPL LTPKSVSVIT VDGHRFIKVD CSNYDLLEDG LNVTVPYSNA PDVQNSTKPS
VFFTVADNLK NGNLNDPDHT VAQALKGLVQ KEKIDTNKVV YNGSIGVYSG SWIINTVEGM
LSATMVSGNT SGISTSATQD VHGVNPDQMK IYGSIINATN NQVANAYQII NIPDSQDKVS
QFTPTMSGQA SLIDAVNGTD LSSAGELLYS TALTDLNNAQ AAAADGHWLT ADQITNWSKV
KSVMLKFDSK ALPARTSARV EIPLVDKDIY QHVGKSISVS SAIFSENKAS SNSNLPNLTI
LPGKPASAKL TVTGQAKVNV KVHYKDDQGN DHYVDLPDQA KTYHEGQDIM KPEDFMTKNS
DLTDADRILL PAGIVINWAA GPTIQNSDAQ YAAGYQNGTA AFDQTVAPDF DGDTLIYEGA
FAKPVTDTHK VTRTIKFVDQ NGKQIYPDVA QHSIEFTRSG FEDPFTHKIA WAEIPGSDIL
PQYQVPKIDG YTPDESQVAQ ATVKFGDPDS AITVTYKANS QVIKVNFIDD TTGETLNSKS
LDGISDADAN YNTKADINNY EKQHYVLVRD SSDGQDLIFD HDDQATQSYD VHFTHDTKPD
SRQDTVTRTI TYTGAGNKTP SAVTQSVHFT QAGTKDLVTG KTKWNDVADQ NFVSVGTPEV
AGYTPDKSQV AQATVKYGDK DTTVTVTYAA DKQQAKLRFY DDTAKKFIDA APVLDASGKT
DGQVGFTIPN SYDFSKYNFV NVTKGADPES TDQLAGADLS AVQYGKYDTD DKKDQVFVAH
FTHKIKAINE KVTVNETIHY VYEDGSKAHD DYQATPLVFT KTGTKDLVTG EEKATWTKSQ
KFAEVASPEI PGYTPDQAVV PAVEVAHGDN DVVRTVTYSK NIEPQEPTTP TDNPDTPTDI
PDNPVTPKAP EEPQQPATPD DNLDVVRPHS DNSPQKKQDS KQTNKTTEVN KTVKRSSTVK
PKATATTKRN GTKVQLATKD ASKQSNPKAV VNSTSMTVVN NKGEKKAETL PQTGEKDNKL
GILGLLTLSL ASLFGFSEKK KKED
//
