ID V5HAM3_IXORI Unreviewed; 263 AA.
AC V5HAM3;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=BPTI/Kunitz inhibitor domain-containing protein {ECO:0000259|PROSITE:PS50279};
OS Ixodes ricinus (Common tick) (Acarus ricinus).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC Parasitiformes; Ixodida; Ixodoidea; Ixodidae; Ixodinae; Ixodes.
OX NCBI_TaxID=34613 {ECO:0000313|EMBL:JAB70123.1};
RN [1] {ECO:0000313|EMBL:JAB70123.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Salivary gland and midgut {ECO:0000313|EMBL:JAB70123.1};
RX PubMed=25765539;
RA Kotsyfakis M., Schwarz A., Erhart J., Ribeiro J.M.;
RT "Tissue- and time-dependent transcription in Ixodes ricinus salivary glands
RT and midguts when blood feeding on the vertebrate host.";
RL Sci. Rep. 5:9103-9103(2015).
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DR EMBL; GANP01014345; JAB70123.1; -; mRNA.
DR AlphaFoldDB; V5HAM3; -.
DR GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:UniProtKB-KW.
DR GO; GO:0044562; P:envenomation resulting in negative regulation of voltage-gated potassium channel activity in another organism; IEA:UniProt.
DR CDD; cd22625; Kunitz_ixolaris_1; 1.
DR Gene3D; 4.10.410.10; Pancreatic trypsin inhibitor Kunitz domain; 3.
DR InterPro; IPR002223; Kunitz_BPTI.
DR InterPro; IPR036880; Kunitz_BPTI_sf.
DR PANTHER; PTHR45938; ACP24A4-RELATED; 1.
DR PANTHER; PTHR45938:SF11; PAPILIN; 1.
DR Pfam; PF00014; Kunitz_BPTI; 2.
DR SMART; SM00131; KU; 2.
DR SUPFAM; SSF57362; BPTI-like; 3.
DR PROSITE; PS50279; BPTI_KUNITZ_2; 2.
PE 2: Evidence at transcript level;
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..263
FT /note="BPTI/Kunitz inhibitor domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004737842"
FT DOMAIN 28..80
FT /note="BPTI/Kunitz inhibitor"
FT /evidence="ECO:0000259|PROSITE:PS50279"
FT DOMAIN 200..249
FT /note="BPTI/Kunitz inhibitor"
FT /evidence="ECO:0000259|PROSITE:PS50279"
SQ SEQUENCE 263 AA; 29821 MW; 259C4937D0F2C851 CRC64;
MQKEIAWTLI AAALGICSGQ KSQEEDICFY KPELGQGYNI VKGWSYDPDL DKCYAFYHAS
RRVYGIENIF QNESACNQRC RPRVPAKCYA KPPQRKGRSD LPVVTYDPKT GKCLDIRATQ
QSQSENVFNN RGSCTKECRD TDLRLCLNPN ENDCEYIDGQ SYRYDSGKQT CEEADDGSSG
GFKSAEDCFK RCGILVDNKC TLPIQNITTC EETQERYGYN KKTGQCEEIL GCADGGNSFE
EAEKCWKDCA PTSRCKYETR HWA
//
