ID V5HUC2_IXORI Unreviewed; 938 AA.
AC V5HUC2;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 24-JAN-2024, entry version 33.
DE RecName: Full=Pre-mRNA-processing factor 6 {ECO:0000256|ARBA:ARBA00020235};
DE AltName: Full=PRP6 homolog {ECO:0000256|ARBA:ARBA00032140};
DE AltName: Full=U5 snRNP-associated 102 kDa protein {ECO:0000256|ARBA:ARBA00031070};
DE Flags: Fragment;
OS Ixodes ricinus (Common tick) (Acarus ricinus).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC Parasitiformes; Ixodida; Ixodoidea; Ixodidae; Ixodinae; Ixodes.
OX NCBI_TaxID=34613 {ECO:0000313|EMBL:JAB77873.1};
RN [1] {ECO:0000313|EMBL:JAB77873.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Salivary gland and midgut {ECO:0000313|EMBL:JAB77873.1};
RX PubMed=25765539;
RA Kotsyfakis M., Schwarz A., Erhart J., Ribeiro J.M.;
RT "Tissue- and time-dependent transcription in Ixodes ricinus salivary glands
RT and midguts when blood feeding on the vertebrate host.";
RL Sci. Rep. 5:9103-9103(2015).
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DR EMBL; GANP01006595; JAB77873.1; -; mRNA.
DR AlphaFoldDB; V5HUC2; -.
DR GO; GO:0000398; P:mRNA splicing, via spliceosome; IEA:InterPro.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 4.
DR InterPro; IPR003107; HAT.
DR InterPro; IPR010491; PRP1_N.
DR InterPro; IPR045075; Syf1-like.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR11246; PRE-MRNA SPLICING FACTOR; 1.
DR PANTHER; PTHR11246:SF1; PRE-MRNA-PROCESSING FACTOR 6; 1.
DR Pfam; PF06424; PRP1_N; 1.
DR Pfam; PF13428; TPR_14; 1.
DR Pfam; PF14559; TPR_19; 1.
DR SMART; SM00386; HAT; 14.
DR SMART; SM00028; TPR; 2.
DR SUPFAM; SSF48452; TPR-like; 3.
PE 2: Evidence at transcript level;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 22..174
FT /note="PRP1 splicing factor N-terminal"
FT /evidence="ECO:0000259|Pfam:PF06424"
FT REGION 24..100
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 165..189
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 110..153
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 47..70
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 165..182
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:JAB77873.1"
SQ SEQUENCE 938 AA; 105663 MW; 3AA721233E2DDD49 CRC64;
AAMAAPTSLV AKKKKHFLGI PAPLGYVAGV GRGATGFTTR SDIGPARDAS DVPDDRHAPP
NKRTKKQKEE EEDDEEDLND SNYDEFAGYG GSLFSKDPYD KDDEEADAIY EAIDRRMDEK
RKDYREMKLR RELERYRQER PKIQQQFSDL KRDLSQVTED DWKAIPEVGD ARNKRQRNPR
PEKFTPMPDS ILAKAGIGSE SVTTLDPRQQ AYGSGLTTPF PGTATPGWAT PSADLDLRKI
GQARNTLMDI KLNQVSDSVS GQTVVDPKGY LTDLQSMIPS HGADISDIKK ARLLLKSVRE
TNPNHPPAWI ASARLEEVTG KIQTARNLIM KGGEMCPNSE DIWLEASRLQ PTDLAKAVIA
QAVRQIPNSV RLWIKASELE GELKAKKRVF RKALETIPNS VRLWKAAVEL EEPEDARILL
SRAVECCPTS VELWLALARL ENYDNARKVL NKARENIPTD RQIWITAAKL EEANNNAHMV
EKIIDRAITS LRANGVEINR EQWLKDAVEC EKSQSILTCQ GIIRTVVGIG VEDEDRKHAW
MEDAEAVAAQ GAQECARAIY AHALSVFPSK KSIWLRAAYF EKSCGTRETL EALLQRAVAH
CPKAEVLWLM GAKSKWMAGD IPAARSILSL AFQANPNSEE IWLAAVKLES ENNEFERARR
LLAKARSSAP TARVMMKSVR LEWALGDLRM ASELLEEGLR LYADFPKLWM MKGQILQSQG
QTDEARATYN QGLKKCPTSV PLWLLLSRLE ESGGALTKAR SVLEKARLRN PCHPELWLEA
VRVEARAGFK EIALTLMAKA MQDCPGSGIL WSEAIFMEPR PQRKTKSVDA LKRCEHDPYV
LLAVSKLFWT ERKTNKVREW LNRTVKIEPD LGDAWAYFYK FELLHGSEEQ QEEVKRRCIL
AEPRHGPNWC KVSKDIVNWR KKTEDILVLV AASLPLPT
//
