ID V5HYY5_IXORI Unreviewed; 680 AA.
AC V5HYY5;
DT 22-JAN-2014, integrated into UniProtKB/TrEMBL.
DT 22-JAN-2014, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE RecName: Full=Kelch-like protein diablo {ECO:0000256|ARBA:ARBA00013699};
DE Flags: Fragment;
OS Ixodes ricinus (Common tick) (Acarus ricinus).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC Parasitiformes; Ixodida; Ixodoidea; Ixodidae; Ixodinae; Ixodes.
OX NCBI_TaxID=34613 {ECO:0000313|EMBL:JAB79878.1};
RN [1] {ECO:0000313|EMBL:JAB79878.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Salivary gland and midgut {ECO:0000313|EMBL:JAB79878.1};
RX PubMed=25765539;
RA Kotsyfakis M., Schwarz A., Erhart J., Ribeiro J.M.;
RT "Tissue- and time-dependent transcription in Ixodes ricinus salivary glands
RT and midguts when blood feeding on the vertebrate host.";
RL Sci. Rep. 5:9103-9103(2015).
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DR EMBL; GANP01004590; JAB79878.1; -; mRNA.
DR AlphaFoldDB; V5HYY5; -.
DR UniPathway; UPA00143; -.
DR GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR CDD; cd18502; BACK_NS1BP_IVNS1ABP; 1.
DR CDD; cd18306; BTB_POZ_NS1BP; 1.
DR Gene3D; 1.25.40.420; -; 1.
DR Gene3D; 2.120.10.80; Kelch-type beta propeller; 2.
DR InterPro; IPR017096; BTB-kelch_protein.
DR InterPro; IPR000210; BTB/POZ_dom.
DR InterPro; IPR015915; Kelch-typ_b-propeller.
DR InterPro; IPR006652; Kelch_1.
DR InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR PANTHER; PTHR24412:SF396; INFLUENZA VIRUS NS1A-BINDING PROTEIN; 1.
DR PANTHER; PTHR24412; KELCH PROTEIN; 1.
DR Pfam; PF00651; BTB; 1.
DR Pfam; PF01344; Kelch_1; 6.
DR PIRSF; PIRSF037037; Kelch-like_protein_gigaxonin; 2.
DR PRINTS; PR00501; KELCHREPEAT.
DR SMART; SM00225; BTB; 1.
DR SMART; SM00612; Kelch; 6.
DR SUPFAM; SSF117281; Kelch motif; 2.
DR SUPFAM; SSF54695; POZ domain; 1.
DR PROSITE; PS50097; BTB; 1.
PE 2: Evidence at transcript level;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203};
KW Kelch repeat {ECO:0000256|ARBA:ARBA00022441};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786}.
FT DOMAIN 26..98
FT /note="BTB"
FT /evidence="ECO:0000259|PROSITE:PS50097"
FT REGION 254..305
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 658..680
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 256..276
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 659..680
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:JAB79878.1"
SQ SEQUENCE 680 AA; 74217 MW; 586CDEEA05223B43 CRC64;
LVFDDSAHLN KVLMNLNKLR KNKQFCDVVL HVGSGQDMHE IYAHRAVVAS VSPYLFELLA
QKTKGTMQNQ CKINGNFDIS AFERLVDYAY TSRLEVPKPK MKAMYLVAAK LRVQPVTKYC
GKYLVEHLTP DNCTGVRAIL VESMDQELVA EVDAYVRDNI AEVLKSKELQ SLPHIQVELV
QHSNVEMDAT NNKHLCHMVL DWMRASFDQE GVLMETLTEK VHMLYLNLDR TLHDCNDIET
GDSKDTEMIQ DYKRLSRRLS QPNGSKSKSK TKGRAGVTVS NPAKPRQFLY TRSDSSGSSS
SDEEDRDWKI IATTSTGAHS TMGLAVVSGS MIVLSVVQRL NFNGAAATGD SSPEVCGGGV
GYTTLPPMMS SRCGMGTVEF QGKLLVCGGY DRGECLRTVE SYDLGTNRWS PLVSMGTPRG
RVDVTVLHGH VYVIGGSDGT KELASAEVFD GAAWRPLPAL GVARSNAGVC NLDGKVFVVG
GWNGQRGLTC CDVFDPLTRT WCGVAPMQLG RYQAGVACLN REVYAVGGCD SWTCVASVEK
YNPSTNTWVQ VAPLQNARRG CGLVEYNGKL YAVGGHDGVR SLCSVEVYDA QTNTWSPGPS
LTSCRANVGV AVVGGRLFAV GGFNGKAFLN TVEFLDARTN EWTTFVAKAP VAYQVGGGVI
HEDHDEDRDS SREGSAEEFR
//
