ID V5RYL4_9BACT Unreviewed; 346 AA.
AC V5RYL4;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 24-JAN-2024, entry version 42.
DE RecName: Full=phenylalanine--tRNA ligase {ECO:0000256|ARBA:ARBA00012814};
DE EC=6.1.1.20 {ECO:0000256|ARBA:ARBA00012814};
GN ORFNames=RAAC3_TM7C00001G0881 {ECO:0000313|EMBL:AHB42719.1};
OS Candidatus Saccharibacteria bacterium RAAC3_TM7_1.
OC Bacteria; Candidatus Saccharibacteria.
OX NCBI_TaxID=1394711 {ECO:0000313|EMBL:AHB42719.1, ECO:0000313|Proteomes:UP000018523};
RN [1] {ECO:0000313|EMBL:AHB42719.1, ECO:0000313|Proteomes:UP000018523}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RAAC3_TM7_1 {ECO:0000313|EMBL:AHB42719.1,
RC ECO:0000313|Proteomes:UP000018523};
RA Kantor R.S., Wrighton K.C., Handley K.M., Sharon I., Hug L.A.,
RA Castelle C.J., Thomas B.C., Banfield J.F.;
RT "Small genomes and sparse metabolisms of sediment-associated bacteria from
RT four candidate phyla.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + L-phenylalanine + tRNA(Phe) = AMP + diphosphate + H(+) +
CC L-phenylalanyl-tRNA(Phe); Xref=Rhea:RHEA:19413, Rhea:RHEA-COMP:9668,
CC Rhea:RHEA-COMP:9699, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:33019, ChEBI:CHEBI:58095, ChEBI:CHEBI:78442,
CC ChEBI:CHEBI:78531, ChEBI:CHEBI:456215; EC=6.1.1.20;
CC Evidence={ECO:0000256|ARBA:ARBA00000395};
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DR EMBL; CP006915; AHB42719.1; -; Genomic_DNA.
DR AlphaFoldDB; V5RYL4; -.
DR STRING; 1394711.RAAC3_TM7C00001G0881; -.
DR KEGG; sbe:RAAC3_TM7C01G0881; -.
DR PATRIC; fig|1394711.4.peg.800; -.
DR HOGENOM; CLU_025086_0_1_0; -.
DR BioCyc; CSAC1394711:G132K-881-MONOMER; -.
DR Proteomes; UP000018523; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0004826; F:phenylalanine-tRNA ligase activity; IEA:UniProtKB-EC.
DR GO; GO:0000049; F:tRNA binding; IEA:InterPro.
DR GO; GO:0043039; P:tRNA aminoacylation; IEA:InterPro.
DR CDD; cd00496; PheRS_alpha_core; 1.
DR InterPro; IPR006195; aa-tRNA-synth_II.
DR InterPro; IPR045864; aa-tRNA-synth_II/BPL/LPL.
DR InterPro; IPR002319; Phenylalanyl-tRNA_Synthase.
DR PANTHER; PTHR11538:SF41; PHENYLALANINE--TRNA LIGASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR11538; PHENYLALANYL-TRNA SYNTHETASE; 1.
DR Pfam; PF01409; tRNA-synt_2d; 1.
DR SUPFAM; SSF55681; Class II aaRS and biotin synthetases; 1.
DR PROSITE; PS50862; AA_TRNA_LIGASE_II; 1.
PE 4: Predicted;
KW Ligase {ECO:0000313|EMBL:AHB42719.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000018523}.
FT DOMAIN 200..325
FT /note="Aminoacyl-transfer RNA synthetases class-II family
FT profile"
FT /evidence="ECO:0000259|PROSITE:PS50862"
SQ SEQUENCE 346 AA; 38819 MW; 08728776A7C4E1C6 CRC64;
MNYQDKISAV REKLLGRYET LEAKGDILKA PELRELFGLI PSLEAGDRAA FGQAINALAG
ELKEKVAAEN DKEGALPPLD VTAPFDMNAG LPSLLPSEQG TVHPISAEIQ NIADIFYRMG
FSYFSSREID DQYHMFETLN FPKGHPARDD YDTFMTEETD KAGEALVAPA HTSTMQNRIL
TKLKPKLENG EAIAGVSIDR VFRNEDLDAR HEHTFYQCEG VYVAKGVHAG MLVATLKEFL
ESYYEKELDV QINPYYFPFT EPSFEFSLSC PFCDQKGCQV CSYEGWIELL GCGMIHPNVL
KAAGIDPEVY TGFAWGVGVD RLVMMKHGIE DVRHFESAKL DFLRQF
//
