ID V5TM04_HALHI Unreviewed; 540 AA.
AC V5TM04;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 24-JAN-2024, entry version 38.
DE SubName: Full=Xanthine permease {ECO:0000313|EMBL:AHB66381.1};
GN ORFNames=HISP_10315 {ECO:0000313|EMBL:AHB66381.1};
OS Haloarcula hispanica N601.
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Halobacteriales;
OC Haloarculaceae; Haloarcula.
OX NCBI_TaxID=1417673 {ECO:0000313|Proteomes:UP000018572};
RN [1] {ECO:0000313|EMBL:AHB66381.1, ECO:0000313|Proteomes:UP000018572}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=N601 {ECO:0000313|EMBL:AHB66381.1,
RC ECO:0000313|Proteomes:UP000018572};
RX PubMed=24625874;
RA Ding J.Y., Chiang P.W., Hong M.J., Dyall-Smith M., Tang S.L.;
RT "Complete Genome Sequence of the Extremely Halophilic Archaeon Haloarcula
RT hispanica Strain N601.";
RL Genome Announc. 2:e00178-14(2014).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CP006884; AHB66381.1; -; Genomic_DNA.
DR RefSeq; WP_014040782.1; NC_023013.1.
DR AlphaFoldDB; V5TM04; -.
DR GeneID; 23805359; -.
DR KEGG; hhn:HISP_10315; -.
DR HOGENOM; CLU_017959_5_4_2; -.
DR Proteomes; UP000018572; Chromosome 1.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0071702; P:organic substance transport; IEA:UniProt.
DR InterPro; IPR006043; NCS2.
DR NCBIfam; NF037981; NCS2_1; 1.
DR PANTHER; PTHR11119:SF3; LD30822P; 1.
DR PANTHER; PTHR11119; XANTHINE-URACIL / VITAMIN C PERMEASE FAMILY MEMBER; 1.
DR Pfam; PF00860; Xan_ur_permease; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 46..67
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 73..92
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 104..122
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 134..153
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 160..177
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 197..214
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 226..254
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 274..295
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 389..407
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 419..437
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 470..493
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 1..29
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..18
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 540 AA; 56060 MW; 677A8F24DB1EEA03 CRC64;
MTDATPPDDG QNPTTPEEPE TAGFVEYGID DKPPRKQAIL LGVQHYLTMI GASVAIPLGL
AGAMGMFEAA PDQVGRLIGT FFVVSGIATL AQTTLGNRYP IVQGGTFSML APGLAIIGVL
AQQGADWQTM LVELQGAVIV AGIVEVVIGY SGLMGKLKRY VGPVVIAPVI ALIGLSLFNV
PQIANPNFGN PGTGQNWWLL GLTMLSIIAC SQYLDRRHRA FKLFPVLLGI LFAWTVAAIL
SVTGVFAAGS VSYVSLGSVT NAPLVQPIYP FQWGLPQFTP GFIVGMFAGM LASVVESFGD
YHSVARIAGR GAPNSRRIND GIGMEGVGNV FAGIMGTGNG CTSYTENVGA IAITGVASRY
VVQIGAAVMI LVGYFGPAGQ LFATIPSPII GGLYIVMFGQ IAAVGLSQLK YVDLDANRNV
FIVGFALFAG LAVPEYMSQV GQGMDVGSAT ALQQGLAAVP VLGSVLGTDV VATTLFVMGG
TGMVVGGIVA FVLDNTVPGT REERGLAAWA ALTEDDSEYV SSLDRIRGRG GDRPAAVSDD
//
