ID V5XF26_MYCNE Unreviewed; 435 AA.
AC V5XF26;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 24-JAN-2024, entry version 38.
DE RecName: Full=HNH nuclease domain-containing protein {ECO:0000259|SMART:SM00507};
GN ORFNames=D174_18465 {ECO:0000313|EMBL:AHC26428.1};
OS Mycolicibacterium neoaurum VKM Ac-1815D.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycolicibacterium.
OX NCBI_TaxID=700508 {ECO:0000313|EMBL:AHC26428.1, ECO:0000313|Proteomes:UP000018763};
RN [1] {ECO:0000313|EMBL:AHC26428.1, ECO:0000313|Proteomes:UP000018763}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=VKM Ac-1815D {ECO:0000313|EMBL:AHC26428.1,
RC ECO:0000313|Proteomes:UP000018763};
RX PubMed=24435872;
RA Shtratnikova V.Y., Bragin E.Y., Dovbnya D.V., Pekov Y.A., Schelkunov M.I.,
RA Strizhov N., Ivashina T.V., Ashapkin V.V., Donova M.V.;
RT "Complete Genome Sequence of Sterol-Transforming Mycobacterium neoaurum
RT Strain VKM Ac-1815D.";
RL Genome Announc. 2:e01177-13(2014).
CC -!- SIMILARITY: Belongs to the Rv1128c/1148c/1588c/1702c/1945/3466 family.
CC {ECO:0000256|ARBA:ARBA00023450}.
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DR EMBL; CP006936; AHC26428.1; -; Genomic_DNA.
DR RefSeq; WP_023986005.1; NC_023036.2.
DR AlphaFoldDB; V5XF26; -.
DR KEGG; mne:D174_18465; -.
DR eggNOG; COG1403; Bacteria.
DR HOGENOM; CLU_057500_1_0_11; -.
DR Proteomes; UP000018763; Chromosome.
DR GO; GO:0004519; F:endonuclease activity; IEA:InterPro.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd00085; HNHc; 1.
DR Gene3D; 1.10.30.50; -; 1.
DR InterPro; IPR003870; DUF222.
DR InterPro; IPR002711; HNH.
DR InterPro; IPR003615; HNH_nuc.
DR Pfam; PF02720; DUF222; 1.
DR Pfam; PF01844; HNH; 1.
DR SMART; SM00507; HNHc; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000018763}.
FT DOMAIN 306..357
FT /note="HNH nuclease"
FT /evidence="ECO:0000259|SMART:SM00507"
FT REGION 139..160
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 197..217
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 385..435
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 144..159
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 197..216
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 435 AA; 47552 MW; 716E7006DDD41832 CRC64;
MPPPTTPYAA DVVNSVSDRL SALYDEAAEL VGQRNALDGR LVEIVAEIDG GDGPSLWGHT
GCRSLSELVA WRLGMSPRNA QVMVAIAQRL EVFPRLAANL RQGQMSLDQF GVIAEHAADG
SDDHYAELAT MATVTQLRTA VKQEPRPQPE RRDGSVRSFS RCEQDGCTTY RIRLPRLEAA
KFDAALGAHR EGLVADWRRD HDNPDADGRD GRDGVEVPPF PDTVDALMSM VESGWDAEAA
ARPHGARTTV VVHYDVEKGS AALHLGPVLA EWERQFLLCD ASCEVWLERH GTPMGAGRST
RTISRRLRRA LEHRDGTCAV PGCGATRGLH AHHLVHWEHG GATELENLVL LCPFHHRLHH
KGEITIVGPA DRLVVTDCEG RRLTGASLAR PPTGPPPDVP PCRGPKGERA QWMWYTPFEP
EPPPGTKELA GDPGR
//
