ID   V6AUU2_9ARCH            Unreviewed;       444 AA.
AC   V6AUU2;
DT   19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT   19-FEB-2014, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   SubName: Full=Putative ThiF family protein {ECO:0000313|EMBL:CDI06310.1};
GN   ORFNames=NITUZ_40476 {ECO:0000313|EMBL:CDI06310.1};
OS   Candidatus Nitrosotenuis uzonensis.
OC   Archaea; Nitrososphaerota; Nitrosotenuis.
OX   NCBI_TaxID=1407055 {ECO:0000313|EMBL:CDI06310.1, ECO:0000313|Proteomes:UP000018159};
RN   [1] {ECO:0000313|EMBL:CDI06310.1, ECO:0000313|Proteomes:UP000018159}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=N4 {ECO:0000313|EMBL:CDI06310.1,
RC   ECO:0000313|Proteomes:UP000018159};
RX   DOI=10.1371/journal.pone.0080835;
RA   Lebedeva E.V., Hatzenpichler R., Pelletier E., Schuster N., Hauzmayer S.,
RA   Bulaev A., Grigor'eva N.V., Galushko A., Schmid M., Palatinszky M.,
RA   Le Paslier D., Daims H., Wagner M.;
RT   "Enrichment and Genome Sequence of the Group I.1a Ammonia-Oxidizing
RT   Archaeon ?Ca. Nitrosotenuis uzonensis? Representing a Clade Globally.";
RL   PLoS ONE 0:0-0(2013).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CDI06310.1}.
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DR   EMBL; CBTY010000009; CDI06310.1; -; Genomic_DNA.
DR   RefSeq; WP_048196672.1; NZ_CBTY010000009.1.
DR   AlphaFoldDB; V6AUU2; -.
DR   STRING; 1407055.NITUZ_40476; -.
DR   OrthoDB; 7915at2157; -.
DR   Proteomes; UP000018159; Unassembled WGS sequence.
DR   GO; GO:0008641; F:ubiquitin-like modifier activating enzyme activity; IEA:InterPro.
DR   CDD; cd00757; ThiF_MoeB_HesA_family; 1.
DR   Gene3D; 3.10.20.30; -; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR012675; Beta-grasp_dom_sf.
DR   InterPro; IPR016155; Mopterin_synth/thiamin_S_b.
DR   InterPro; IPR045886; ThiF/MoeB/HesA.
DR   InterPro; IPR000594; ThiF_NAD_FAD-bd.
DR   InterPro; IPR003749; ThiS/MoaD-like.
DR   InterPro; IPR035985; Ubiquitin-activating_enz.
DR   PANTHER; PTHR10953:SF102; ADENYLYLTRANSFERASE AND SULFURTRANSFERASE MOCS3; 1.
DR   PANTHER; PTHR10953; UBIQUITIN-ACTIVATING ENZYME E1; 1.
DR   Pfam; PF00899; ThiF; 1.
DR   Pfam; PF02597; ThiS; 1.
DR   SUPFAM; SSF69572; Activating enzymes of the ubiquitin-like proteins; 1.
DR   SUPFAM; SSF54285; MoaD/ThiS; 1.
PE   4: Predicted;
FT   DOMAIN          103..335
FT                   /note="THIF-type NAD/FAD binding fold"
FT                   /evidence="ECO:0000259|Pfam:PF00899"
SQ   SEQUENCE   444 AA;  48426 MW;  A8D1F8F2A375526E CRC64;
     MADITFTIPS VLNKGGGEKK LQISANSLLE SFNKVSETMG DDFKRRVLND DGTPRSLVNI
     YINGKNSRFS GGINTELKDG DEVYILPAVA GGSDLSSKEI DRYSRQIMLE EIGYQGQQKL
     RAAKVCVVGV GGLGNPITTR LAAMGIGKLR IIDRDVIELS NLHRQTMYDE DDVGQVKVEV
     AARKLKKLNP DVEIESLPIS INDYTALDAV EGCDVVIDAL DSVNARYALN KACVEKKIPF
     VTGAAVGVSG QAFTILPKQS ACYSCMFPAL DEDSMPTCSI EGVHPSILSI VGGIEVAEAV
     KIILGKKPSL SDKILHIDIE TMAFDFTRTF RAEECYVCGT GKLESAPKQE LIIEELCGRN
     RGKRTFSITP TQKFEIDTEQ ITNIAKDLQF RVENQGELGL SMRTNELSVS FMKRGSAVIV
     GPKDETDAVS LYKKLLGKKQ VVPS
//