ID   V6DNF8_9LACO            Unreviewed;       786 AA.
AC   V6DNF8;
DT   19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT   19-FEB-2014, sequence version 1.
DT   24-JAN-2024, entry version 32.
DE   RecName: Full=Probable phosphoketolase {ECO:0000256|HAMAP-Rule:MF_01403};
DE            EC=4.1.2.- {ECO:0000256|HAMAP-Rule:MF_01403};
GN   ORFNames=LSCP400_09801 {ECO:0000313|EMBL:CDK35173.1};
OS   Ligilactobacillus salivarius cp400.
OC   Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC   Ligilactobacillus.
OX   NCBI_TaxID=1273133 {ECO:0000313|EMBL:CDK35173.1, ECO:0000313|Proteomes:UP000018601};
RN   [1] {ECO:0000313|EMBL:CDK35173.1, ECO:0000313|Proteomes:UP000018601}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cp400 {ECO:0000313|Proteomes:UP000018601};
RX   PubMed=24526652; DOI=10.1128/genomeA.01231-13;
RA   Mackenzie D.A., McLay K., Roos S., Walter J., Swarbreck D., Drou N.,
RA   Crossman L.C., Juge N.;
RT   "Draft Genome Sequence of a Novel Lactobacillus salivarius Strain Isolated
RT   from Piglet.";
RL   Genome Announc. 2:e01231-e01213(2014).
CC   -!- COFACTOR:
CC       Name=thiamine diphosphate; Xref=ChEBI:CHEBI:58937;
CC         Evidence={ECO:0000256|ARBA:ARBA00001964,
CC         ECO:0000256|HAMAP-Rule:MF_01403};
CC   -!- SIMILARITY: Belongs to the XFP family. {ECO:0000256|ARBA:ARBA00005623,
CC       ECO:0000256|HAMAP-Rule:MF_01403}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CDK35173.1}.
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DR   EMBL; CBVR010000012; CDK35173.1; -; Genomic_DNA.
DR   AlphaFoldDB; V6DNF8; -.
DR   Proteomes; UP000018601; Unassembled WGS sequence.
DR   GO; GO:0016832; F:aldehyde-lyase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   CDD; cd02011; TPP_PK; 1.
DR   Gene3D; 3.40.50.920; -; 1.
DR   Gene3D; 3.40.50.970; -; 2.
DR   HAMAP; MF_01403; Phosphoketolase; 1.
DR   InterPro; IPR023962; Phosphoketolase.
DR   InterPro; IPR029061; THDP-binding.
DR   InterPro; IPR009014; Transketo_C/PFOR_II.
DR   InterPro; IPR005593; Xul5P/Fru6P_PKetolase.
DR   InterPro; IPR018969; Xul5P/Fru6P_PKetolase_C.
DR   InterPro; IPR019790; Xul5P/Fru6P_PKetolase_CS.
DR   InterPro; IPR018970; Xul5P/Fru6P_PKetolase_N.
DR   InterPro; IPR019789; Xul5P/Fru6P_PKetolase_ThDP_BS.
DR   PANTHER; PTHR31273; PHOSPHOKETOLASE-RELATED; 1.
DR   PANTHER; PTHR31273:SF0; PHOSPHOKETOLASE-RELATED; 1.
DR   Pfam; PF03894; XFP; 1.
DR   Pfam; PF09363; XFP_C; 1.
DR   Pfam; PF09364; XFP_N; 1.
DR   PIRSF; PIRSF017245; Phosphoketolase; 1.
DR   SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 2.
DR   PROSITE; PS60002; PHOSPHOKETOLASE_1; 1.
DR   PROSITE; PS60003; PHOSPHOKETOLASE_2; 1.
PE   3: Inferred from homology;
KW   Lyase {ECO:0000256|ARBA:ARBA00023239, ECO:0000256|HAMAP-Rule:MF_01403};
KW   Thiamine pyrophosphate {ECO:0000256|ARBA:ARBA00023052, ECO:0000256|HAMAP-
KW   Rule:MF_01403}.
FT   DOMAIN          6..366
FT                   /note="Xylulose 5-phosphate/Fructose 6-phosphate
FT                   phosphoketolase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF09364"
FT   DOMAIN          583..782
FT                   /note="Xylulose 5-phosphate/Fructose 6-phosphate
FT                   phosphoketolase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF09363"
SQ   SEQUENCE   786 AA;  88679 MW;  D1B7BEFADD65FE63 CRC64;
     MTDYSSQEYL DKLDAYWRAA NYVSVGQLYL KDNPLLRRPL KAEDVKVKPI GHWGTIAGQN
     FIYAHLNRVI NKYDLNMFYV EGPGHGGQVM VSNSYLDGSY SEIYPEISQD EQGMKRLFKR
     FSFPGGVASH AAPETPGSIH EGGELGYSIS HSVGAVLDNP DLIVAAVVGD GEAETGPLAA
     SWQSNKFINP IHDGAVLPIL DLNGFKISNP TILSRESDET LTKYFEGMGW HPIFVEGDDP
     KLMHPAMAKA MDEAIEEIKA IQKNARENND PNLPAWPVII FRAPKGWTGP KEWDGEPIEK
     SFRAHQIPIP VDQNDMQHAD ALVDWLESYK PEELFDENGK LKAEIAEITP KGDKRMAANP
     HTNPGKLIRE VIKPDFRDFA VDTSVPGKEV AQDMTVLGKY LEKVLSDNRH NYRVFGPDET
     MSNRLAPIFD VTKRQWLAEI KEPNDQYLAP SGQVIDSQLS EHQAEGFLEG YVLTGRHGFF
     ASYESFLRVV DSMLTQHFKW LRKATEQPWR TSIPSLNVIA TSTVFQQDHN GYTHQDPGIL
     GHLADKKPEY IREYLPADAN SLLAVFDKTI NDRDKINLIV ASKHPRQQFY SAAEAKELVD
     KGLKIIDWAS TDKNAEPDVV IAAAGTEPNL EALAAISILH EKLPDLKIRF INVVDILKLR
     SPKVDPRGLS DDEFDAYFTK DKPVIFAFHG YEGLLRDIFY YRHNHNVAFH GYRENGDITT
     PFDMRVLSQM DRFDLVKSVA LSLPNADKYG QLVAEMDAKV AKHHQYIRDE GTDLPEVENW
     EWKPLD
//