ID V6JGN9_STRRC Unreviewed; 420 AA.
AC V6JGN9;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=MFS transporter {ECO:0000313|EMBL:EST19020.1};
GN ORFNames=M878_42915 {ECO:0000313|EMBL:EST19020.1};
OS Streptomyces roseochromogenus subsp. oscitans DS 12.976.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1352936 {ECO:0000313|EMBL:EST19020.1, ECO:0000313|Proteomes:UP000017984};
RN [1] {ECO:0000313|EMBL:EST19020.1, ECO:0000313|Proteomes:UP000017984}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DS 12.976 {ECO:0000313|EMBL:EST19020.1,
RC ECO:0000313|Proteomes:UP000017984};
RX PubMed=24407645;
RA Ruckert C., Kalinowski J., Heide L., Apel A.K.;
RT "Draft Genome Sequence of Streptomyces roseochromogenes subsp. oscitans DS
RT 12.976, Producer of the Aminocoumarin Antibiotic Clorobiocin.";
RL Genome Announc. 2:e01147-e01113(2014).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EST19020.1}.
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DR EMBL; AWQX01000385; EST19020.1; -; Genomic_DNA.
DR RefSeq; WP_023553397.1; NZ_CM002285.1.
DR AlphaFoldDB; V6JGN9; -.
DR STRING; 1352936.M878_42915; -.
DR PATRIC; fig|1352936.5.peg.8885; -.
DR HOGENOM; CLU_035002_0_0_11; -.
DR OrthoDB; 9810492at2; -.
DR Proteomes; UP000017984; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 2.
DR InterPro; IPR011701; MFS.
DR InterPro; IPR020846; MFS_dom.
DR InterPro; IPR036259; MFS_trans_sf.
DR PANTHER; PTHR23517:SF16; PROTEIN, PUTATIVE-RELATED; 1.
DR PANTHER; PTHR23517; RESISTANCE PROTEIN MDTM, PUTATIVE-RELATED-RELATED; 1.
DR Pfam; PF07690; MFS_1; 2.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
DR PROSITE; PS50850; MFS; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000017984};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 20..39
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 59..78
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 90..107
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 154..176
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 182..198
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 303..322
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 328..348
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 369..389
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 395..414
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 237..420
FT /note="Major facilitator superfamily (MFS) profile"
FT /evidence="ECO:0000259|PROSITE:PS50850"
SQ SEQUENCE 420 AA; 43973 MW; E4073BAD5E0539F3 CRC64;
MSTRTESAAE PVRLGLRENW LQFTLLVVVN VCVGGLVGLE RTTVPLIGAH TFRLANDLAV
FSFIIAFGLT KALTNLAAGA LTARFRRKRL LVTGWLIGVP VPFALAWAPS WGWIVAANVL
LGLNQGLTWS MTVNMKIDLV GPARRGLATG LNEAAGYTAV GTTALVTGYL ATAYGLRPVP
ELIGVIFVAA GLGLALIVRD TAAHVALELS QHTKPLPSSE STALRATFAR TSWHHRSLRG
ASQAGLVNNL NDGLTWGVFP LLFTDHGLGI AAVGLIKGLY PILWGLGQIP TGHLSDRIGR
KPLIVTGMLV QATGFVLALA LLDTPLLAGV LSAIALGLGT AMVYPALIAS VSDHAHPAWR
ANALGTYRFW RDIGYAAGAL VAGILADALG LNATVVAAAV LTAGSGLLAA HWISEHDTAR
//
