ID V6JKS8_STRNV Unreviewed; 551 AA.
AC V6JKS8;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=FAD-binding dehydrogenase {ECO:0000313|EMBL:EST20527.1};
GN ORFNames=M877_33515 {ECO:0000313|EMBL:EST20527.1};
OS Streptomyces niveus NCIMB 11891.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1352941 {ECO:0000313|EMBL:EST20527.1, ECO:0000313|Proteomes:UP000017971};
RN [1] {ECO:0000313|EMBL:EST20527.1, ECO:0000313|Proteomes:UP000017971}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NCIMB 11891 {ECO:0000313|EMBL:EST20527.1,
RC ECO:0000313|Proteomes:UP000017971};
RX PubMed=24407644;
RA Flinspach K., Ruckert C., Kalinowski J., Heide L., Apel A.K.;
RT "Draft Genome Sequence of Streptomyces niveus NCIMB 11891, Producer of the
RT Aminocoumarin Antibiotic Novobiocin.";
RL Genome Announc. 2:e01146-e01113(2014).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EST20527.1}.
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DR EMBL; AWQW01000263; EST20527.1; -; Genomic_DNA.
DR RefSeq; WP_023542761.1; NZ_CM002280.1.
DR AlphaFoldDB; V6JKS8; -.
DR STRING; 193462.BBN63_28105; -.
DR PATRIC; fig|1352941.4.peg.6804; -.
DR eggNOG; COG3573; Bacteria.
DR HOGENOM; CLU_022946_0_0_11; -.
DR OrthoDB; 9813348at2; -.
DR Proteomes; UP000017971; Chromosome.
DR GO; GO:0033765; F:steroid dehydrogenase activity, acting on the CH-CH group of donors; IEA:UniProt.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR Gene3D; 3.90.700.10; Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain; 1.
DR InterPro; IPR003953; FAD-binding_2.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR014614; KsdD_DH.
DR InterPro; IPR027477; Succ_DH/fumarate_Rdtase_cat_sf.
DR PANTHER; PTHR43260; 3-KETOSTEROID-DELTA-1-DEHYDROGENASE; 1.
DR PANTHER; PTHR43260:SF1; KSDD-LIKE STEROID DEHYDROGENASE RV0785; 1.
DR Pfam; PF00890; FAD_binding_2; 1.
DR PIRSF; PIRSF036654; UCP036654; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
PE 4: Predicted;
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
FT DOMAIN 6..532
FT /note="FAD-dependent oxidoreductase 2 FAD binding"
FT /evidence="ECO:0000259|Pfam:PF00890"
SQ SEQUENCE 551 AA; 59673 MW; F1A53B146DC6DE3D CRC64;
MAYDADVIVI GAGLAGLVAT AELVDAGRSV ILLDQEPEAS IGGQAHWSFG GLFLVDSPEQ
RRLRVKDSRE LALQDWLGTA GFDRDEDHWP REWAEAYVDF AAGEKRSWLR ERGVRFFPVV
GWAERGGYGA RGHGNSVPRF HITWGTGPGV VAPFERKVRE GVAKGLVTFR FRHRVTGLAA
TAGAVDTVTG EVLEPSDAER GTASSRVTTD TFELRGQAVI VTSGGIGGNH DLVRAQWPER
LGTPPEKMLS GVPAHVDGLM LGITERAGAH HINRDRMWHY TEGIENWNPI WARHGIRILP
GPSSLWLDAR GRRLPVPLFP GFDTLGTLDH IMHSGHDHTW FVLNQRIIGK EFALSGSEQN
PDLTGKSVRD VINRARLDVP GPVKAFMDNG ADFVVEKDLA ALVRGMNALT DKPLIDEAEL
RREITARDRE VANPFTKDLQ MTAVRGARAF LGDKLIRTVA PHRVLDPKAG PLIAVRLHIL
TRKSLGGLQT DLSSRVLRAD GTPLAGVYAA GEAAGFGGGG MHGYRSLEGT FLGGCVFSGR
AAGRAAAEAV A
//
