ID   V6JRL6_STRRC            Unreviewed;       944 AA.
AC   V6JRL6;
DT   19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT   19-FEB-2014, sequence version 1.
DT   24-JAN-2024, entry version 43.
DE   SubName: Full=RNA helicase {ECO:0000313|EMBL:EST21736.1};
GN   ORFNames=M878_36390 {ECO:0000313|EMBL:EST21736.1};
OS   Streptomyces roseochromogenus subsp. oscitans DS 12.976.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=1352936 {ECO:0000313|EMBL:EST21736.1, ECO:0000313|Proteomes:UP000017984};
RN   [1] {ECO:0000313|EMBL:EST21736.1, ECO:0000313|Proteomes:UP000017984}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DS 12.976 {ECO:0000313|EMBL:EST21736.1,
RC   ECO:0000313|Proteomes:UP000017984};
RX   PubMed=24407645;
RA   Ruckert C., Kalinowski J., Heide L., Apel A.K.;
RT   "Draft Genome Sequence of Streptomyces roseochromogenes subsp. oscitans DS
RT   12.976, Producer of the Aminocoumarin Antibiotic Clorobiocin.";
RL   Genome Announc. 2:e01147-e01113(2014).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EST21736.1}.
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DR   EMBL; AWQX01000316; EST21736.1; -; Genomic_DNA.
DR   AlphaFoldDB; V6JRL6; -.
DR   STRING; 1352936.M878_36390; -.
DR   PATRIC; fig|1352936.5.peg.7563; -.
DR   HOGENOM; CLU_002902_4_1_11; -.
DR   Proteomes; UP000017984; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   CDD; cd18795; SF2_C_Ski2; 1.
DR   Gene3D; 1.10.3380.30; -; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR001650; Helicase_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR012961; Ski2/MTR4_C.
DR   PANTHER; PTHR12131; ATP-DEPENDENT RNA AND DNA HELICASE; 1.
DR   PANTHER; PTHR12131:SF8; HELICASE SKI2W; 1.
DR   Pfam; PF00270; DEAD; 1.
DR   Pfam; PF08148; DSHCT; 1.
DR   Pfam; PF00271; Helicase_C; 1.
DR   SMART; SM00487; DEXDc; 1.
DR   SMART; SM01142; DSHCT; 1.
DR   SMART; SM00490; HELICc; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR   PROSITE; PS51194; HELICASE_CTER; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:EST21736.1};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000017984}.
FT   DOMAIN          53..211
FT                   /note="Helicase ATP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51192"
FT   DOMAIN          332..495
FT                   /note="Helicase C-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51194"
FT   REGION          260..285
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          654..696
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   944 AA;  105165 MW;  6A26FBC2D4DB7BE6 CRC64;
     MAPGTLESTM TEDLSPAERY AAARRRAAEQ ATALASFREM YDFGLDPFQI EACEALETGK
     GVLVAAPTGS GKTIVGEFAV HLALRQGKKC FYTTPIKALS NQKYADLCRR YGDGMVGLLT
     GDNSINSDAP VVVMTTEVLR NMLYAGSQTL LGLGYVVMDE VHYLSDRFRG AVWEEVIIHL
     PESVTLVSLS ATVSNAEEFG DWLDTVRGDT EVIVSEHRPV PLFQHVLAGR RMYDLFEEGE
     GHKKAVNPDL ARLARMEATR PSYQDRRRGR AMREADRERE RRQRSRVWTP GRPEVIERLD
     SEGLLPAITF IFSRAACEAA VQQCLYAGLR LNDEEAREQV RALVEERTAS IPSEDLHVLG
     YYEWLEGLER GIAAHHAGML PTFKEVVEEL FVRGLVKAVF ATETLALGIN MPARSVVLEK
     LVKWNGEQHA DITPGEYTQL TGRAGRRGID IEGHAVVLWQ RGMSPEHLAG LAGTRTYPLR
     SSFKPSYNMA VNLVEQFGRH RSRELLETSF AQFQADKSVV GISRQVQRNE EGLAGYKASM
     TCHLGDFEEY ARLRRELKDR ETELARQGAN ERRAEAAVAL EKLKPGDVIH VPTGKYAGLA
     LVLDPGLPAG RSNGHRGFDH HDGPRPLVLT AERQVKRLAS MDFPVPVEPL DRMRIPKSFN
     PRSPQSRRDL ASALRSKAGH IPPERARKKR SQAADDREIA RLRTAIRAHS CHGCNDREDH
     ARWAERYHRL LRDTSQLERR IEGRTNTIAR TFDRIVALLT ELDYLRGDEV TEHGKRLARL
     YGELDLLASE CLRERVWEGL APAELAACVS ALVYEARVSD DAMAPKLPSG KAKAALGEMV
     RIWGRLDGLE EEFRINQTEG VGQREPDLGF AWAAYMWASG KGLDEVLREA DMPAGDFVRW
     CKQVIDVLGQ ISAAAPVEGS TVAKAARKAV DQLLRGVVAY SSVG
//