ID V6JT24_STRNV Unreviewed; 598 AA.
AC V6JT24;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 24-JAN-2024, entry version 30.
DE SubName: Full=2-oxoglutarate ferredoxin oxidoreductase subunit alpha {ECO:0000313|EMBL:EST22261.1};
DE Flags: Fragment;
GN ORFNames=M877_15875 {ECO:0000313|EMBL:EST27846.1}, M877_30335
GN {ECO:0000313|EMBL:EST22261.1};
OS Streptomyces niveus NCIMB 11891.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1352941 {ECO:0000313|EMBL:EST22261.1, ECO:0000313|Proteomes:UP000017971};
RN [1] {ECO:0000313|EMBL:EST22261.1, ECO:0000313|Proteomes:UP000017971}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NCIMB 11891 {ECO:0000313|EMBL:EST22261.1,
RC ECO:0000313|Proteomes:UP000017971};
RX PubMed=24407644;
RA Flinspach K., Ruckert C., Kalinowski J., Heide L., Apel A.K.;
RT "Draft Genome Sequence of Streptomyces niveus NCIMB 11891, Producer of the
RT Aminocoumarin Antibiotic Novobiocin.";
RL Genome Announc. 2:e01146-e01113(2014).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EST22261.1}.
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DR EMBL; AWQW01000216; EST22261.1; -; Genomic_DNA.
DR EMBL; AWQW01000115; EST27846.1; -; Genomic_DNA.
DR AlphaFoldDB; V6JT24; -.
DR STRING; 193462.BBN63_13300; -.
DR PATRIC; fig|1352941.4.peg.3233; -.
DR eggNOG; COG0674; Bacteria.
DR eggNOG; COG1014; Bacteria.
DR HOGENOM; CLU_456026_0_0_11; -.
DR Proteomes; UP000017971; Chromosome.
DR GO; GO:0000287; F:magnesium ion binding; IEA:UniProt.
DR GO; GO:0016903; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors; IEA:InterPro.
DR CDD; cd07034; TPP_PYR_PFOR_IOR-alpha_like; 1.
DR Gene3D; 3.40.50.920; -; 1.
DR Gene3D; 3.40.50.970; -; 1.
DR Gene3D; 3.40.920.10; Pyruvate-ferredoxin oxidoreductase, PFOR, domain III; 1.
DR InterPro; IPR022367; 2-oxoacid/accept_OxRdtase_asu.
DR InterPro; IPR033412; PFOR_II.
DR InterPro; IPR019752; Pyrv/ketoisovalerate_OxRed_cat.
DR InterPro; IPR002880; Pyrv_Fd/Flavodoxin_OxRdtase_N.
DR InterPro; IPR002869; Pyrv_flavodox_OxRed_cen.
DR InterPro; IPR029061; THDP-binding.
DR InterPro; IPR009014; Transketo_C/PFOR_II.
DR NCBIfam; TIGR03710; OAFO_sf; 1.
DR PANTHER; PTHR32154:SF20; 2-OXOGLUTARATE OXIDOREDUCTASE SUBUNIT KORA; 1.
DR PANTHER; PTHR32154; PYRUVATE-FLAVODOXIN OXIDOREDUCTASE-RELATED; 1.
DR Pfam; PF17147; PFOR_II; 1.
DR Pfam; PF01558; POR; 1.
DR Pfam; PF01855; POR_N; 1.
DR SUPFAM; SSF53323; Pyruvate-ferredoxin oxidoreductase, PFOR, domain III; 1.
DR SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 1.
DR SUPFAM; SSF52922; TK C-terminal domain-like; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
FT DOMAIN 1..187
FT /note="Pyruvate/ketoisovalerate oxidoreductase catalytic"
FT /evidence="ECO:0000259|Pfam:PF01558"
FT DOMAIN 242..456
FT /note="Pyruvate flavodoxin/ferredoxin oxidoreductase
FT pyrimidine binding"
FT /evidence="ECO:0000259|Pfam:PF01855"
FT DOMAIN 497..566
FT /note="Pyruvate:ferredoxin oxidoreductase core"
FT /evidence="ECO:0000259|Pfam:PF17147"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EST22261.1"
SQ SEQUENCE 598 AA; 64416 MW; C9B5E30E76A41558 CRC64;
DGMQLTGDRF TSETASFGND LSTLPNFPAE IRAPAGTLPG VSSFQLHFAD HDILTPGDAP
NVLVAMNPAA LKANIADVPR GADIIVNTDE FTKRPMAKVG YLTSPLEDGS LEAYQLHPVP
LTTLTIEALK DFGLSRKEAE RSKNMFALGL LSWMYHRPTE GTEQFLRTKF AKKPNIAEAN
VAAFRAGWNF GETTEDFAVS YEVAPATTAF PTGTYRNISG NLALSYGLIA ASHQADLPLY
LGSYPITPAS DILHELSRHK NFGVRTFQAE DEIAAIGAAL GAAFGGSLAV TTTSGPGVAL
KSETIGLAVS LELPLLVVAI QRGGPSTGLP TKTEQADLLQ AMYGRNGEAP VPVVAPRTPA
DCFDAAIEAA RIAVTYRTPV FLLSDGYLAN GSEPWRIPEP GELPDLGVQF ASGPNHTLPD
GTEVFWPYKR DPHTLARPWA VPGTPGLEHR IGGIEKQDGT GNISYDPANH DFMVRTRQAK
IDNIQVPDLT VDDPHRARTL VLGWGSTYGP ITAAVRRLRT AGHPIAQAHL RHINPFPRNL
GDILKRYDKV VVPEMNLGQL AALLRAKYLI DAHSYNQVNG MPFKAEQLAT ALKEAIDA
//
