ID   V6K0I5_STRNV            Unreviewed;       559 AA.
AC   V6K0I5;
DT   19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT   19-FEB-2014, sequence version 1.
DT   24-JAN-2024, entry version 29.
DE   RecName: Full=DUF4331 domain-containing protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=M877_21345 {ECO:0000313|EMBL:EST25730.1};
OS   Streptomyces niveus NCIMB 11891.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=1352941 {ECO:0000313|EMBL:EST25730.1, ECO:0000313|Proteomes:UP000017971};
RN   [1] {ECO:0000313|EMBL:EST25730.1, ECO:0000313|Proteomes:UP000017971}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NCIMB 11891 {ECO:0000313|EMBL:EST25730.1,
RC   ECO:0000313|Proteomes:UP000017971};
RX   PubMed=24407644;
RA   Flinspach K., Ruckert C., Kalinowski J., Heide L., Apel A.K.;
RT   "Draft Genome Sequence of Streptomyces niveus NCIMB 11891, Producer of the
RT   Aminocoumarin Antibiotic Novobiocin.";
RL   Genome Announc. 2:e01146-e01113(2014).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EST25730.1}.
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DR   EMBL; AWQW01000147; EST25730.1; -; Genomic_DNA.
DR   RefSeq; WP_023540465.1; NZ_CM002280.1.
DR   AlphaFoldDB; V6K0I5; -.
DR   PATRIC; fig|1352941.4.peg.4355; -.
DR   eggNOG; ENOG502Z7P1; Bacteria.
DR   HOGENOM; CLU_025722_0_0_11; -.
DR   OrthoDB; 9791748at2; -.
DR   Proteomes; UP000017971; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR025566; DUF4331.
DR   Pfam; PF14224; DUF4331; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        531..551
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   REGION          41..62
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          273..314
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        279..293
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   559 AA;  58504 MW;  650CA95F9DB2B645 CRC64;
     MTMRSFHLPG RKPASRRAER ALASVGTLAL VGAAAVTGLA PATSSASSHR EAPMTAGDPR
     ADNTDVYAFT SPDKPDTVTL VANWIPFQEP NGGPNFYPFA NDARYNIKID ANGDGKPDTT
     YTWEFTDHIR DSADQFLYNT GVVKNLDDPT LNFRQTYDLT VTDSAGNRRT LLDDAPAAPS
     NVGKASMPDY ASLREQAVKQ LPDGGQTLAG QTSDPFFADL RIFDLLYGGN LSETGHNTLA
     GYNVNTIAIQ VPKKSVALKG DATRNPVIGV WSTTDREGAD VTGGKDGENA DAVDGKGTDG
     QAGGTPDKGG EDGWRQVSRL GNPLVNEVVV PLKYKDAFNA LSPDKDASVT PVVNAVKDPI
     VPKLVQSIYG VPAPATPRND LVEIFLTGIC KACGPIKADL NAQQLNADAD KSAIVPAEEL
     RLNMSVPPAA KPNRLGVLGK DLAGFPNGRR LNDDVVDIEL QALEGAAQTG KIVPALAAGD
     KVDTPYREPG DSFPYVALPN TAAVNQADSL HPDGGVGAGL GGNAFGGGFP VGPVAAVGGG
     ALLTCAGVMA LRRRRAERV
//