ID V6TKV2_GIAIN Unreviewed; 343 AA.
AC V6TKV2;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 28-JUN-2023, entry version 25.
DE SubName: Full=Glucokinase {ECO:0000313|EMBL:ESU39618.1};
GN ORFNames=DHA2_8826 {ECO:0000313|EMBL:ESU39618.1};
OS Giardia intestinalis (Giardia lamblia).
OC Eukaryota; Metamonada; Diplomonadida; Hexamitidae; Giardiinae; Giardia.
OX NCBI_TaxID=5741 {ECO:0000313|EMBL:ESU39618.1, ECO:0000313|Proteomes:UP000018320};
RN [1] {ECO:0000313|Proteomes:UP000018320}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=DH {ECO:0000313|Proteomes:UP000018320};
RA Adam R., Dahlstrom E., Martens C., Bruno D., Barbian K., Porcella S.F.,
RA Nash T.;
RT "Genome sequencing of Giardia lamblia Genotypes A2 and B isolates (DH and
RT GS) and comparative analysis with the genomes of Genotypes A1 and E (WB and
RT Pig).";
RL Submitted (FEB-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ESU39618.1, ECO:0000313|Proteomes:UP000018320}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DH {ECO:0000313|EMBL:ESU39618.1,
RC ECO:0000313|Proteomes:UP000018320};
RX PubMed=24307482; DOI=10.1093/gbe/evt197;
RA Adam R.D., Dahlstrom E.W., Martens C.A., Bruno D.P., Barbian K.D.,
RA Ricklefs S.M., Hernandez M.M., Narla N.P., Patel R.B., Porcella S.F.,
RA Nash T.E.;
RT "Genome sequencing of Giardia lamblia genotypes A2 and B isolates (DH and
RT GS) and comparative analysis with the genomes of genotypes A1 and E (WB and
RT Pig).";
RL Genome Biol. Evol. 5:2498-2511(2013).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ESU39618.1}.
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DR EMBL; AHGT01000002; ESU39618.1; -; Genomic_DNA.
DR AlphaFoldDB; V6TKV2; -.
DR EnsemblProtists; ESU39618; ESU39618; DHA2_8826.
DR VEuPathDB; GiardiaDB:DHA2_8826; -.
DR VEuPathDB; GiardiaDB:GL50581_943; -.
DR VEuPathDB; GiardiaDB:GL50803_008826; -.
DR VEuPathDB; GiardiaDB:QR46_1892; -.
DR Proteomes; UP000018320; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0004340; F:glucokinase activity; IEA:InterPro.
DR GO; GO:0005536; F:glucose binding; IEA:InterPro.
DR GO; GO:0006096; P:glycolytic process; IEA:InterPro.
DR Gene3D; 3.30.420.40; -; 1.
DR Gene3D; 3.40.367.20; -; 1.
DR InterPro; IPR043129; ATPase_NBD.
DR InterPro; IPR003836; Glucokinase.
DR PANTHER; PTHR47363; GLUCOKINASE; 1.
DR PANTHER; PTHR47363:SF1; GLUCOKINASE; 1.
DR Pfam; PF02685; Glucokinase; 1.
DR SUPFAM; SSF53067; Actin-like ATPase domain; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:ESU39618.1};
KW Transferase {ECO:0000313|EMBL:ESU39618.1}.
SQ SEQUENCE 343 AA; 37685 MW; A0DE9D03BAFA89C0 CRC64;
MPYSLSGDLG GTKCFLAIHD LDVLKTDPRA APLLEHELLC KDYQSTGDLI NDFLKRWDRE
TPIVGCLGVA GPVTNGRVCI TNLDWNESEE ELQNTTGVGK MKLINDFAAI GYGLLAIRPD
DYLDFDARNG SVSTPTVVPD NSTGIVSYAG AGTGFGVGFV ADGVAYAAEG GHTTFSPMEA
EDHALAQFIK EKYNTDHVSF ERVVSGLGLR NMHDFFWKNL SGLASPALRE HVLSRDHDID
MGFLAKCAET GDKYALKIFK KFFYYYGFYL GNICVLFRPK DYFIAGGILA KDLNLVCGPC
REDFCRGLYT KGRMSHLPNG VSFHVVTNQK LGIVGAAYFC TKM
//
