ID V6U1J7_GIAIN Unreviewed; 593 AA.
AC V6U1J7;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=Ankyrin repeat protein {ECO:0000313|EMBL:ESU43130.1};
GN ORFNames=GSB_150419 {ECO:0000313|EMBL:ESU43130.1};
OS Giardia intestinalis (Giardia lamblia).
OC Eukaryota; Metamonada; Diplomonadida; Hexamitidae; Giardiinae; Giardia.
OX NCBI_TaxID=5741 {ECO:0000313|EMBL:ESU43130.1, ECO:0000313|Proteomes:UP000018040};
RN [1] {ECO:0000313|Proteomes:UP000018040}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=GS {ECO:0000313|Proteomes:UP000018040};
RA Adam R., Dahlstrom E., Martens C., Bruno D., Barbian K., Porcella S.F.,
RA Nash T.;
RT "Genome sequencing of Giardia lamblia Genotypes A2 and B isolates (DH and
RT GS) and comparative analysis with the genomes of Genotypes A1 and E (WB and
RT Pig).";
RL Submitted (FEB-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ESU43130.1, ECO:0000313|Proteomes:UP000018040}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=GS {ECO:0000313|EMBL:ESU43130.1,
RC ECO:0000313|Proteomes:UP000018040};
RX PubMed=24307482; DOI=10.1093/gbe/evt197;
RA Adam R.D., Dahlstrom E.W., Martens C.A., Bruno D.P., Barbian K.D.,
RA Ricklefs S.M., Hernandez M.M., Narla N.P., Patel R.B., Porcella S.F.,
RA Nash T.E.;
RT "Genome sequencing of Giardia lamblia genotypes A2 and B isolates (DH and
RT GS) and comparative analysis with the genomes of genotypes A1 and E (WB and
RT Pig).";
RL Genome Biol. Evol. 5:2498-2511(2013).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ESU43130.1}.
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DR EMBL; AHHH01000059; ESU43130.1; -; Genomic_DNA.
DR AlphaFoldDB; V6U1J7; -.
DR EnsemblProtists; ESU43130; ESU43130; GSB_150419.
DR VEuPathDB; GiardiaDB:DHA2_151595; -.
DR VEuPathDB; GiardiaDB:GL50581_2341; -.
DR VEuPathDB; GiardiaDB:GL50803_003147; -.
DR VEuPathDB; GiardiaDB:QR46_2056; -.
DR Proteomes; UP000018040; Unassembled WGS sequence.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 5.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR PANTHER; PTHR24120:SF4; ANKYRIN REPEAT AND SOCS BOX PROTEIN 12; 1.
DR PANTHER; PTHR24120; GH07239P; 1.
DR Pfam; PF00023; Ank; 1.
DR Pfam; PF12796; Ank_2; 4.
DR SMART; SM00248; ANK; 15.
DR SUPFAM; SSF48403; Ankyrin repeat; 2.
DR PROSITE; PS50297; ANK_REP_REGION; 1.
DR PROSITE; PS50088; ANK_REPEAT; 1.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023}.
FT REPEAT 258..280
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
SQ SEQUENCE 593 AA; 65272 MW; EC5713DCAE89574E CRC64;
MHRKVAEYEI CSNVTPLFDA VRNNNVEQVQ KSLSYAGIYD SMGMTALMHA ARHNYLDIVK
VLEPLEGHLE GPRGETVLMH AAECGAFETS QYILSFQGYI KSDKLPGNCL KNAMLAGEVQ
CAELFYENEK DILEITPLMW AAFVGNIPVV QEEILLKDNL RKRTCDGYTA LMFAACSNQT
QAIELLLPYE ATLRDDSEET ALMHAAQNSS ISAAHLLVER EIGLSTKLGN TALYIAAAQG
CVEIVKMTME QEHSILFNGF SALYIAADGG HLDCVKILIQ YLDKFKKSSD TGLSGAAASG
HTEIVKFLIP YEAKVRVDGD GTTALMYAAQ NNQIKCVRML KDYELGLVNN SGLTALSMAA
MNGSSKIVSL LIDELSVITE DVVSPLEMCF SSNNFEPISL LLPREKDRVG ANNLMVYACT
GRREAMRQLR PMLLQQQDLG GRTALMYAVI GKQLNCAKDL LAESRITDNE GRTALMYAVF
LEPDECLPFL KLLTGLTGVQ DESGETALIK AASVSNHIAV KYLAQYERRM VSKDGDTALL
VAARTDAYKC VEYLLEEADI VDQFGSTALE NAESYGGYNV YQMLKNSQRA LIM
//
