ID V6U3F5_GIAIN Unreviewed; 528 AA.
AC V6U3F5;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=Translation initiation factor beta propellor-like domain-containing protein {ECO:0000259|Pfam:PF08662};
GN ORFNames=GSB_9899 {ECO:0000313|EMBL:ESU45536.1};
OS Giardia intestinalis (Giardia lamblia).
OC Eukaryota; Metamonada; Diplomonadida; Hexamitidae; Giardiinae; Giardia.
OX NCBI_TaxID=5741 {ECO:0000313|EMBL:ESU45536.1, ECO:0000313|Proteomes:UP000018040};
RN [1] {ECO:0000313|Proteomes:UP000018040}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=GS {ECO:0000313|Proteomes:UP000018040};
RA Adam R., Dahlstrom E., Martens C., Bruno D., Barbian K., Porcella S.F.,
RA Nash T.;
RT "Genome sequencing of Giardia lamblia Genotypes A2 and B isolates (DH and
RT GS) and comparative analysis with the genomes of Genotypes A1 and E (WB and
RT Pig).";
RL Submitted (FEB-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ESU45536.1, ECO:0000313|Proteomes:UP000018040}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=GS {ECO:0000313|EMBL:ESU45536.1,
RC ECO:0000313|Proteomes:UP000018040};
RX PubMed=24307482; DOI=10.1093/gbe/evt197;
RA Adam R.D., Dahlstrom E.W., Martens C.A., Bruno D.P., Barbian K.D.,
RA Ricklefs S.M., Hernandez M.M., Narla N.P., Patel R.B., Porcella S.F.,
RA Nash T.E.;
RT "Genome sequencing of Giardia lamblia genotypes A2 and B isolates (DH and
RT GS) and comparative analysis with the genomes of genotypes A1 and E (WB and
RT Pig).";
RL Genome Biol. Evol. 5:2498-2511(2013).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ESU45536.1}.
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DR EMBL; AHHH01000004; ESU45536.1; -; Genomic_DNA.
DR AlphaFoldDB; V6U3F5; -.
DR EnsemblProtists; ESU45536; ESU45536; GSB_9899.
DR VEuPathDB; GiardiaDB:DHA2_9899; -.
DR VEuPathDB; GiardiaDB:GL50581_4293; -.
DR VEuPathDB; GiardiaDB:GL50803_009899; -.
DR VEuPathDB; GiardiaDB:QR46_0692; -.
DR Proteomes; UP000018040; Unassembled WGS sequence.
DR GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
DR InterPro; IPR011387; TIF2A.
DR InterPro; IPR013979; TIF_beta_prop-like.
DR PANTHER; PTHR13227; EUKARYOTIC TRANSLATION INITIATION FACTOR 2A; 1.
DR PANTHER; PTHR13227:SF0; EUKARYOTIC TRANSLATION INITIATION FACTOR 2A; 1.
DR Pfam; PF08662; eIF2A; 1.
PE 4: Predicted;
KW Initiation factor {ECO:0000256|ARBA:ARBA00022540};
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917}.
FT DOMAIN 375..483
FT /note="Translation initiation factor beta propellor-like"
FT /evidence="ECO:0000259|Pfam:PF08662"
SQ SEQUENCE 528 AA; 58855 MW; 1E25ABE89B542647 CRC64;
MQPIITNSAD GAQVWSFDGA KLTLTETLSQ QQVKCAAAIT RSDNLMLVFL TGQQQVTCRI
YESTLQRDKL LQECTHTMPH PIESFTLSQY GTFIQLHCNV QHPLDNFLLI DTLSGDILAS
MHSTIRLASF RSMSWPYCLS EDEDYVLFQD GWLLCLKQYD LASRSLKDCG CLSAIPRDQA
WRHVAYHFTP TLKIPSDNLD KYSVVVCIPS QGNSPGYTIV YKLSQFVELS SAELEEGRAT
NKKPAAIADK IMVKPYMHST TAVCDVFVFK PGESGAWFLL LEKTDVDTSK ANNYYGGTIL
RHFCIINKAT TTVTDGKSYV HDFSIKPLAP SDRDSLASGN TSSMNKLVEM FVVTCGVVPP
KVCSYVVTLT NLDRKNASAE LQKDINFGNM PTNSTSWDVA GRYLLLRGEA GMNGDSRILR
PIINNEPKYL AKGTIHSRTH ALFSPRGDAI MYLVTKPRFT VDNGIEIFNM NLKPLAAQPF
EALSSAYFIP YCKSDYTAVG LADEVEGVYL SAMKTETKKY VPPSQRRK
//
