ID V7AXC6_PHAVU Unreviewed; 530 AA.
AC V7AXC6;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 24-JAN-2024, entry version 29.
DE RecName: Full=Endoglucanase {ECO:0000256|RuleBase:RU361166};
DE EC=3.2.1.4 {ECO:0000256|RuleBase:RU361166};
GN ORFNames=PHAVU_009G082800g {ECO:0000313|EMBL:ESW08886.1};
OS Phaseolus vulgaris (Kidney bean) (French bean).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC NPAAA clade; indigoferoid/millettioid clade; Phaseoleae; Phaseolus.
OX NCBI_TaxID=3885 {ECO:0000313|EMBL:ESW08886.1, ECO:0000313|Proteomes:UP000000226};
RN [1] {ECO:0000313|Proteomes:UP000000226}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. G19833 {ECO:0000313|Proteomes:UP000000226};
RX PubMed=24908249; DOI=10.1038/ng.3008;
RA Schmutz J., McClean P.E., Mamidi S., Wu G.A., Cannon S.B., Grimwood J.,
RA Jenkins J., Shu S., Song Q., Chavarro C., Torres-Torres M., Geffroy V.,
RA Moghaddam S.M., Gao D., Abernathy B., Barry K., Blair M., Brick M.A.,
RA Chovatia M., Gepts P., Goodstein D.M., Gonzales M., Hellsten U.,
RA Hyten D.L., Jia G., Kelly J.D., Kudrna D., Lee R., Richard M.M.,
RA Miklas P.N., Osorno J.M., Rodrigues J., Thareau V., Urrea C.A., Wang M.,
RA Yu Y., Zhang M., Wing R.A., Cregan P.B., Rokhsar D.S., Jackson S.A.;
RT "A reference genome for common bean and genome-wide analysis of dual
RT domestications.";
RL Nat. Genet. 46:707-713(2014).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Endohydrolysis of (1->4)-beta-D-glucosidic linkages in
CC cellulose, lichenin and cereal beta-D-glucans.; EC=3.2.1.4;
CC Evidence={ECO:0000256|ARBA:ARBA00000966,
CC ECO:0000256|RuleBase:RU361166};
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 9 (cellulase E) family.
CC {ECO:0000256|ARBA:ARBA00007072, ECO:0000256|PROSITE-ProRule:PRU10059,
CC ECO:0000256|RuleBase:RU361166}.
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DR EMBL; CM002296; ESW08886.1; -; Genomic_DNA.
DR RefSeq; XP_007136892.1; XM_007136830.1.
DR AlphaFoldDB; V7AXC6; -.
DR STRING; 3885.V7AXC6; -.
DR EnsemblPlants; ESW08886; ESW08886; PHAVU_009G082800g.
DR GeneID; 18619514; -.
DR Gramene; ESW08886; ESW08886; PHAVU_009G082800g.
DR KEGG; pvu:PHAVU_009G082800g; -.
DR eggNOG; ENOG502QQ06; Eukaryota.
DR OMA; PSWRGDS; -.
DR OrthoDB; 1347382at2759; -.
DR Proteomes; UP000000226; Chromosome 9.
DR GO; GO:0008810; F:cellulase activity; IEA:UniProtKB-EC.
DR GO; GO:0030245; P:cellulose catabolic process; IEA:UniProtKB-KW.
DR Gene3D; 1.50.10.10; -; 1.
DR InterPro; IPR008928; 6-hairpin_glycosidase_sf.
DR InterPro; IPR012341; 6hp_glycosidase-like_sf.
DR InterPro; IPR001701; Glyco_hydro_9.
DR InterPro; IPR018221; Glyco_hydro_9_His_AS.
DR PANTHER; PTHR22298; ENDO-1,4-BETA-GLUCANASE; 1.
DR PANTHER; PTHR22298:SF104; ENDOGLUCANASE 16; 1.
DR Pfam; PF00759; Glyco_hydro_9; 1.
DR SUPFAM; SSF48208; Six-hairpin glycosidases; 1.
DR PROSITE; PS00592; GH9_2; 1.
PE 3: Inferred from homology;
KW Carbohydrate metabolism {ECO:0000256|ARBA:ARBA00023277,
KW ECO:0000256|PROSITE-ProRule:PRU10059};
KW Cellulose degradation {ECO:0000256|ARBA:ARBA00023001,
KW ECO:0000256|RuleBase:RU361166};
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295, ECO:0000256|PROSITE-
KW ProRule:PRU10059};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW ProRule:PRU10059};
KW Polysaccharide degradation {ECO:0000256|ARBA:ARBA00023326,
KW ECO:0000256|PROSITE-ProRule:PRU10059};
KW Reference proteome {ECO:0000313|Proteomes:UP000000226};
KW Signal {ECO:0000256|RuleBase:RU361166}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|RuleBase:RU361166"
FT CHAIN 21..530
FT /note="Endoglucanase"
FT /evidence="ECO:0000256|RuleBase:RU361166"
FT /id="PRO_5018378594"
FT DOMAIN 77..523
FT /note="Glycoside hydrolase family 9"
FT /evidence="ECO:0000259|Pfam:PF00759"
FT REGION 31..69
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 449
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10059"
SQ SEQUENCE 530 AA; 56716 MW; 5E172AD551D256BC CRC64;
MGNRQVYLAI ILAWLTLFEG NMMVVSGGGG GGGGRGGGGS GGGGGRGGGG SGGGGGGGGS
GGGGGRGGGG GGGGLNYKEA LTKSLIFLEA QRSGKLPKNN RVPWRGDSAL DDGKLVNMDL
VGGYYDAGDN VKYGLPMAFT VTTLAWAAIA YNSEFKSAQE LNNLHAAIRW GTDYFLKATS
RSKTLYVEVG DPNKDHKCWI SPERMKIKRM VKMIGEGTAG SEIAAETAAA MAASSIVFGT
TDRPYSRNLL NKAKLLFDMA KANKGTYDGE CPFYCSYSGF NDELMWAATW LYMATKSSMY
IKFVLEESKS ASVAEFSWDL KYAGAQILLS QLFFEGEQKL ERFKKQADSF ICSVLPDSPY
SQVKLTPGGY IHLRDGANSQ YATSAAYLFS VYSDLLAKYK GKVVCGDKTF GAPRLLAFAK
KQMDYLLGKN PEGRSYMVGF GKNPPTQAHH RGASVPALKK GEEEVNCGMS FVKWFKKDEP
NIHELTGAIV GGPDIGDKFK DKRWESPYTE PCTYVNSLAA GVLAKLASMY
//
