ID V7CS24_PHAVU Unreviewed; 398 AA.
AC V7CS24;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE RecName: Full=Histone deacetylase domain-containing protein {ECO:0000259|Pfam:PF00850};
GN ORFNames=PHAVU_001G034500g {ECO:0000313|EMBL:ESW32992.1};
OS Phaseolus vulgaris (Kidney bean) (French bean).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC NPAAA clade; indigoferoid/millettioid clade; Phaseoleae; Phaseolus.
OX NCBI_TaxID=3885 {ECO:0000313|EMBL:ESW32992.1, ECO:0000313|Proteomes:UP000000226};
RN [1] {ECO:0000313|Proteomes:UP000000226}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. G19833 {ECO:0000313|Proteomes:UP000000226};
RX PubMed=24908249; DOI=10.1038/ng.3008;
RA Schmutz J., McClean P.E., Mamidi S., Wu G.A., Cannon S.B., Grimwood J.,
RA Jenkins J., Shu S., Song Q., Chavarro C., Torres-Torres M., Geffroy V.,
RA Moghaddam S.M., Gao D., Abernathy B., Barry K., Blair M., Brick M.A.,
RA Chovatia M., Gepts P., Goodstein D.M., Gonzales M., Hellsten U.,
RA Hyten D.L., Jia G., Kelly J.D., Kudrna D., Lee R., Richard M.M.,
RA Miklas P.N., Osorno J.M., Rodrigues J., Thareau V., Urrea C.A., Wang M.,
RA Yu Y., Zhang M., Wing R.A., Cregan P.B., Rokhsar D.S., Jackson S.A.;
RT "A reference genome for common bean and genome-wide analysis of dual
RT domestications.";
RL Nat. Genet. 46:707-713(2014).
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947};
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CM002288; ESW32992.1; -; Genomic_DNA.
DR RefSeq; XP_007160998.1; XM_007160936.1.
DR AlphaFoldDB; V7CS24; -.
DR STRING; 3885.V7CS24; -.
DR EnsemblPlants; ESW32992; ESW32992; PHAVU_001G034500g.
DR GeneID; 18640258; -.
DR Gramene; ESW32992; ESW32992; PHAVU_001G034500g.
DR eggNOG; KOG1344; Eukaryota.
DR OMA; GTHHAHY; -.
DR OrthoDB; 239005at2759; -.
DR Proteomes; UP000000226; Chromosome 1.
DR GO; GO:0004407; F:histone deacetylase activity; IEA:UniProtKB-EC.
DR CDD; cd09993; HDAC_classIV; 1.
DR Gene3D; 3.40.800.20; Histone deacetylase domain; 1.
DR InterPro; IPR044150; HDAC_classIV.
DR InterPro; IPR000286; His_deacetylse.
DR InterPro; IPR023801; His_deacetylse_dom.
DR InterPro; IPR037138; His_deacetylse_dom_sf.
DR InterPro; IPR023696; Ureohydrolase_dom_sf.
DR PANTHER; PTHR10625:SF33; HISTONE DEACETYLASE 11; 1.
DR PANTHER; PTHR10625; HISTONE DEACETYLASE HDAC1-RELATED; 1.
DR Pfam; PF00850; Hist_deacetyl; 1.
DR PRINTS; PR01270; HDASUPER.
DR SUPFAM; SSF52768; Arginase/deacetylase; 1.
PE 4: Predicted;
KW Chromatin regulator {ECO:0000256|ARBA:ARBA00022853};
KW Reference proteome {ECO:0000313|Proteomes:UP000000226};
KW Repressor {ECO:0000256|ARBA:ARBA00022491};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 100..381
FT /note="Histone deacetylase"
FT /evidence="ECO:0000259|Pfam:PF00850"
SQ SEQUENCE 398 AA; 44556 MW; 5FB3757CD22F5E5D CRC64;
MQWVRKVYFW IIRVISHSIF GACMKLVNRV SEFSKKNISD SSPPPLLSLS MSSSSVNDTE
ALRRNRILSS KLYFDVSPSK VPLIYSESYD IAFLGIEKLH PFDSSKWGRI CRFLVSFGIL
DKKCIVEPLE ASKDDLLVVH TELYLNRLKE SSKVAMIVEV PPVALIPNCL VQQKLLSPFR
KQVGGTVLAA KLAKERGWAI NVGGGFHHCS AEKGGGFCAY ADISLCIHFA FVRLNISRVM
IIDLDAHQGN GHEMDFAYDS RVYILDMYNP GIYPLDYEAR NYINQKVEVK SGTVTEEYLQ
KLDEALEVAG RRFNPELVIY NAGTDILEGD PLGRLEISPE GIALRDEKVF RFARERNIPI
VMLTSGGYMK SSARVIADSI VNLSKKCLIE TSGAPKSS
//
