ID   V7J806_MYCAV            Unreviewed;       490 AA.
AC   V7J806;
DT   19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT   19-FEB-2014, sequence version 1.
DT   24-JAN-2024, entry version 35.
DE   SubName: Full=Peptidase M28 {ECO:0000313|EMBL:ETA93681.1};
GN   ORFNames=O982_21485 {ECO:0000313|EMBL:ETA93681.1};
OS   Mycobacterium avium 10-5581.
OC   Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium avium complex (MAC).
OX   NCBI_TaxID=1392000 {ECO:0000313|EMBL:ETA93681.1, ECO:0000313|Proteomes:UP000018557};
RN   [1] {ECO:0000313|EMBL:ETA93681.1, ECO:0000313|Proteomes:UP000018557}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=10-5581 {ECO:0000313|EMBL:ETA93681.1,
RC   ECO:0000313|Proteomes:UP000018557};
RA   Bannantine J.P., Robbe-Austerman S., O'Connell C.;
RT   "Genome sequence of MAC strains.";
RL   Submitted (OCT-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ETA93681.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AYNT01000222; ETA93681.1; -; Genomic_DNA.
DR   AlphaFoldDB; V7J806; -.
DR   PATRIC; fig|1392000.4.peg.4574; -.
DR   Proteomes; UP000018557; Unassembled WGS sequence.
DR   GO; GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008235; F:metalloexopeptidase activity; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR   CDD; cd04816; PA_SaNapH_like; 1.
DR   Gene3D; 3.50.30.30; -; 1.
DR   Gene3D; 3.40.630.10; Zn peptidases; 1.
DR   InterPro; IPR045175; M28_fam.
DR   InterPro; IPR046450; PA_dom_sf.
DR   InterPro; IPR003137; PA_domain.
DR   InterPro; IPR007484; Peptidase_M28.
DR   PANTHER; PTHR12147; METALLOPEPTIDASE M28 FAMILY MEMBER; 1.
DR   PANTHER; PTHR12147:SF55; PEPTIDE HYDROLASE; 1.
DR   Pfam; PF02225; PA; 1.
DR   Pfam; PF04389; Peptidase_M28; 1.
DR   SUPFAM; SSF52025; PA domain; 1.
DR   SUPFAM; SSF53187; Zn-dependent exopeptidases; 1.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE   4: Predicted;
KW   Aminopeptidase {ECO:0000256|ARBA:ARBA00022438};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022438};
KW   Protease {ECO:0000256|ARBA:ARBA00022438}; Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..22
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           23..490
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5004761526"
FT   DOMAIN          131..220
FT                   /note="PA"
FT                   /evidence="ECO:0000259|Pfam:PF02225"
FT   DOMAIN          243..460
FT                   /note="Peptidase M28"
FT                   /evidence="ECO:0000259|Pfam:PF04389"
FT   REGION          346..366
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   490 AA;  49821 MW;  7094890FFC1712D8 CRC64;
     MTVRLGATLL WIAVLLAGCS SAGPGLPTAA PDLGHGLAKK VTADAMMAHL RALQNIANAN
     GGNRADGTPG FQASVDYVAK ALRDKGFDVQ TPQFDRLYPV SPGKPTLTVA GRGYPVDQAS
     MLVQTPPGGL TGPAVRPAQP SGCAASDYPG ALPKGAIAVV DDTRCSVVDK QNSAVARGAS
     ALIVVSALDG HGAPPTLFTP GYYKQLSVPV AVVNPSGAAA LAGAGGPVRL ILDAVNVKVT
     SRNVVAQTKT GSAHEVIMVG AHLDGSRAGP GINDNGSGVA AVLETALQLG PLAPVSNAVR
     FVFWGAGEDG LGGVMDYLFG LDRDQLNDIA LYLNFTMLGS PNAGFFTDDG DQSGPPAPGI
     SAADVPEGSA GIERTLAGYL NLAGKRAADM PLNTRADYHP FMVAGVPIGG MTTGASQPKT
     TVQSRLWGGQ AGVPFDPNFQ SPRDTADNIN RDALAVMGSG VGFAVGSYAQ SIGGVNGVPP
     HDKRHRTRVP
//