ID V8CB93_9HELI Unreviewed; 1151 AA.
AC V8CB93;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 24-JAN-2024, entry version 33.
DE RecName: Full=CoA-substrate-specific enzyme activase {ECO:0008006|Google:ProtNLM};
GN ORFNames=HMPREF2086_00723 {ECO:0000313|EMBL:ETD23976.1};
OS Helicobacter macacae MIT 99-5501.
OC Bacteria; Campylobacterota; Epsilonproteobacteria; Campylobacterales;
OC Helicobacteraceae; Helicobacter.
OX NCBI_TaxID=1357400 {ECO:0000313|EMBL:ETD23976.1, ECO:0000313|Proteomes:UP000018731};
RN [1] {ECO:0000313|EMBL:ETD23976.1, ECO:0000313|Proteomes:UP000018731}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MIT 99-5501 {ECO:0000313|EMBL:ETD23976.1,
RC ECO:0000313|Proteomes:UP000018731};
RX PubMed=25212613;
RA Shen Z., Sheh A., Young S.K., Abouelliel A., Ward D.V., Earl A.M.,
RA Fox J.G.;
RT "Draft genome sequences of six enterohepatic helicobacter species isolated
RT from humans and one from rhesus macaques.";
RL Genome Announc. 2:e00857-e00814(2014).
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ETD23976.1}.
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DR EMBL; AZJI01000004; ETD23976.1; -; Genomic_DNA.
DR RefSeq; WP_023927447.1; NZ_KI669454.1.
DR AlphaFoldDB; V8CB93; -.
DR STRING; 1357400.HMPREF2086_00723; -.
DR PATRIC; fig|1357400.3.peg.996; -.
DR eggNOG; COG1924; Bacteria.
DR eggNOG; COG3580; Bacteria.
DR HOGENOM; CLU_002393_3_0_7; -.
DR OrthoDB; 9177882at2; -.
DR Proteomes; UP000018731; Unassembled WGS sequence.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.
DR CDD; cd00012; NBD_sugar-kinase_HSP70_actin; 1.
DR Gene3D; 3.30.420.40; -; 4.
DR InterPro; IPR002731; ATPase_BadF.
DR InterPro; IPR043129; ATPase_NBD.
DR InterPro; IPR018709; CoA_activase_DUF2229.
DR InterPro; IPR008275; CoA_E_activase_dom.
DR NCBIfam; TIGR00241; CoA_E_activ; 1.
DR PANTHER; PTHR32329:SF4; ACTIVATOR OF 2-HYDROXYACYL-COA DEHYDRATASE-RELATED; 1.
DR PANTHER; PTHR32329; BIFUNCTIONAL PROTEIN [INCLUDES 2-HYDROXYACYL-COA DEHYDRATASE (N-TER) AND ITS ACTIVATOR DOMAIN (C_TERM)-RELATED; 1.
DR Pfam; PF01869; BcrAD_BadFG; 2.
DR Pfam; PF09989; DUF2229; 1.
DR SUPFAM; SSF53067; Actin-like ATPase domain; 2.
PE 4: Predicted;
KW Iron {ECO:0000256|ARBA:ARBA00023014};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00023014};
KW Reference proteome {ECO:0000313|Proteomes:UP000018731}.
FT DOMAIN 19..250
FT /note="ATPase BadF/BadG/BcrA/BcrD type"
FT /evidence="ECO:0000259|Pfam:PF01869"
FT DOMAIN 369..623
FT /note="ATPase BadF/BadG/BcrA/BcrD type"
FT /evidence="ECO:0000259|Pfam:PF01869"
FT DOMAIN 724..981
FT /note="DUF2229"
FT /evidence="ECO:0000259|Pfam:PF09989"
FT REGION 250..270
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1151 AA; 127608 MW; 0BD154524D12DF2D CRC64;
MSQIITQTAN STLLQPLLLG IDVGSTTAKI ALLDGEKIIY KRYERHYSKV REKAIEIITD
LRDIVGTREL KVALSGSAGF GIAKAVGIDF VQEVFATAEA VKFLEPDTDA VIELGGEDAK
ILFLSGGSEE RMNGSCAGGT GAFIDQMVTL LAISAQEFDE ISLNHSKIYP VASRCGVFAK
TDVQPLLNQG VDKSNIAASI FQAVVNQTIS GLAQGRKITG KVLFLGGPLF FYKGLQERFA
KTLQEDYEKS ESYERAKNKN PSHTQNTQNP AKSIKPFCAV FPDFAPYAVA IGVARCASES
SKTFSCDSLL ERLEQSKNTA SRNKYLKPLF ASQKELDDFN ARHKKASLKI IDIDEAFEAN
GGKPIEAYLG VDCGSTTTKI ILLDSANNIL YQYYNSNEGN PASVIHSQLK HIYKHYGAQI
FIKGSAVTGY GEELIKSGFG LDAGIVETMA HLKAAQFFNP KVDFIIDIGG QDMKCFYIRN
GTIDSIMLNE ACSSGCGSFI ETFARSMGHS VSEFATLGLK SKHPVELGSR CTVFMNSSVK
EAQKEGASIE DISAGLSMSV VKNAIYKVIR ARDADDLGQQ IVVQGGTFLN DAVLRSFEIE
IARNVIRPEI SGLMGAFGAA LYAKSLGLDK SSILDEHDLE HFSHSASATN CKICGNNCHL
TINKFNDSKG ARKFISGNRC DKPLGIKKQS TLPNMYEYKL NRLKDLTNYK LYENPSQNPK
YKGKIGIPLG LNMYENLPFW HKLFSELGFE VVVSKFSSKD TYQKGQYSIP SDTVCYPAKL
MHGHIEDLLE QGVEAIFYPC MSKGFQNSQN HQDSSTKSYN CPVVAYYPEL LANNVDKLKE
VRFYYPYFGL HKKDNFYRKS SRFFGEMFRD FAKSKSDKKG LKSALKNTLK STIKTTSKML
GLKDFSQKEL KAALDSAYRF REEWLADIRT RGEEILQIIK EQNLKAIVLC GRPYHIDPEI
NHGIDKLINS LGLVVLSEDT IAHLAHAKDL QILNQWSYHS RLYNAAQFVC ENENIELVQL
VSFGCGIDSI TTDEVREILE SKGRFYTQLK IDEISNLGAV KIRIRSLIAA MELASQNHKQ
DSKQLEAKSS LMDSSVLKTQ FNSAVFATKI DNANSTNSEQ SIIFRKRANM AFPSVLATRQ
NLATQATKEN A
//
