ID V8NHN0_OPHHA Unreviewed; 769 AA.
AC V8NHN0;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 24-JAN-2024, entry version 16.
DE SubName: Full=Amine sulfotransferase {ECO:0000313|EMBL:ETE61148.1};
DE Flags: Fragment;
GN Name=Sult3a1 {ECO:0000313|EMBL:ETE61148.1};
GN ORFNames=L345_13103 {ECO:0000313|EMBL:ETE61148.1};
OS Ophiophagus hannah (King cobra) (Naja hannah).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera;
OC Serpentes; Colubroidea; Elapidae; Elapinae; Ophiophagus.
OX NCBI_TaxID=8665 {ECO:0000313|EMBL:ETE61148.1, ECO:0000313|Proteomes:UP000018936};
RN [1] {ECO:0000313|EMBL:ETE61148.1, ECO:0000313|Proteomes:UP000018936}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Blood {ECO:0000313|EMBL:ETE61148.1};
RX PubMed=24297900; DOI=10.1073/pnas.1314702110;
RA Vonk F.J., Casewell N.R., Henkel C.V., Heimberg A.M., Jansen H.J.,
RA McCleary R.J., Kerkkamp H.M., Vos R.A., Guerreiro I., Calvete J.J.,
RA Wuster W., Woods A.E., Logan J.M., Harrison R.A., Castoe T.A.,
RA de Koning A.P., Pollock D.D., Yandell M., Calderon D., Renjifo C.,
RA Currier R.B., Salgado D., Pla D., Sanz L., Hyder A.S., Ribeiro J.M.,
RA Arntzen J.W., van den Thillart G.E., Boetzer M., Pirovano W., Dirks R.P.,
RA Spaink H.P., Duboule D., McGlinn E., Kini R.M., Richardson M.K.;
RT "The king cobra genome reveals dynamic gene evolution and adaptation in the
RT snake venom system.";
RL Proc. Natl. Acad. Sci. U.S.A. 110:20651-20656(2013).
CC -!- SIMILARITY: Belongs to the sulfotransferase 1 family.
CC {ECO:0000256|ARBA:ARBA00005771}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ETE61148.1}.
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DR EMBL; AZIM01004136; ETE61148.1; -; Genomic_DNA.
DR AlphaFoldDB; V8NHN0; -.
DR Proteomes; UP000018936; Unassembled WGS sequence.
DR GO; GO:0008146; F:sulfotransferase activity; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 5.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000863; Sulfotransferase_dom.
DR PANTHER; PTHR11783:SF43; AMINE SULFOTRANSFERASE-RELATED; 1.
DR PANTHER; PTHR11783; SULFOTRANSFERASE SULT; 1.
DR Pfam; PF00685; Sulfotransfer_1; 3.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 4.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000018936};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:ETE61148.1}.
FT DOMAIN 15..93
FT /note="Sulfotransferase"
FT /evidence="ECO:0000259|Pfam:PF00685"
FT DOMAIN 168..268
FT /note="Sulfotransferase"
FT /evidence="ECO:0000259|Pfam:PF00685"
FT DOMAIN 306..524
FT /note="Sulfotransferase"
FT /evidence="ECO:0000259|Pfam:PF00685"
FT NON_TER 769
FT /evidence="ECO:0000313|EMBL:ETE61148.1"
SQ SEQUENCE 769 AA; 89956 MW; 9F698F6F9429FC72 CRC64;
MLDFGYSGRS ASIEYNVHNV DITQLPSPRV IISHLPYYLV PKTLRAKKGK VIYVYRNPKD
ILVSYFHYVN AWSGMENSRN LEEYMQRFLS GNGTVLKICK FIGKELSSQE VDKVVEMSTF
KNMKADPRAN VVKTYEECFG LKNITHLRKG TVGDWKNIMT VSQSESSLWL DHVEGWYAHK
GDFNILFLSY EEMKKDLRSS VPKICNFLGR ELTEKEVDDV VDKATFDNMK MDPRTNYKLM
NPTIADSSKG GIVWYWKNIM TVAQNQIMEI VDKFLCKYKG FYFVRNQTSA ENIDSIENFE
IQDDDTFLIT YPKSGHRDGT ENITLIDRIP WLEYNVFQVD LTSRPSPRVI CSHLPYYLVP
KGLRNKRAKI IYVFRNPKDV LASMYHFHKI SVTLETPKDF DTFLEKFLAG KVGNSLWLDH
IEGWCTHKDD FNILFLSYEE MKKDLRSSVL KICNFLGKEL SEKEVDDVVD KATFDNMKMD
ARANYRFMPS DQIDFSKGDF LRKGTIGDWK NLMTVAQSER FDRIIYVFRN PKDVLVSLYH
FHKISVILET PKDFDTFLEK FLAGKVGHSL WLDHIEGWCT HKDDFNILFL SYEEMKRDLR
SSVLKICNFL GKELSEKEVD DVVDKATFDN MKMDSRANYT FMPSDQIDFS KGDFLRKGKS
NERFDSVFKE RMEKLPFKFC WDIQEDPQPI SSSAEENNIT EDSNIKFCAI VNYNKTYRKL
VIPDIGLQIT CLYYYYFYVV QNARKIISIF SSSEDKILHG DFNFELHVT
//
