ID V8NNY8_OPHHA Unreviewed; 256 AA.
AC V8NNY8;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Cdc42 effector protein 3 {ECO:0000313|EMBL:ETE63252.1};
DE Flags: Fragment;
GN Name=CDC42EP3 {ECO:0000313|EMBL:ETE63252.1};
GN ORFNames=L345_10988 {ECO:0000313|EMBL:ETE63252.1};
OS Ophiophagus hannah (King cobra) (Naja hannah).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera;
OC Serpentes; Colubroidea; Elapidae; Elapinae; Ophiophagus.
OX NCBI_TaxID=8665 {ECO:0000313|EMBL:ETE63252.1, ECO:0000313|Proteomes:UP000018936};
RN [1] {ECO:0000313|EMBL:ETE63252.1, ECO:0000313|Proteomes:UP000018936}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Blood {ECO:0000313|EMBL:ETE63252.1};
RX PubMed=24297900; DOI=10.1073/pnas.1314702110;
RA Vonk F.J., Casewell N.R., Henkel C.V., Heimberg A.M., Jansen H.J.,
RA McCleary R.J., Kerkkamp H.M., Vos R.A., Guerreiro I., Calvete J.J.,
RA Wuster W., Woods A.E., Logan J.M., Harrison R.A., Castoe T.A.,
RA de Koning A.P., Pollock D.D., Yandell M., Calderon D., Renjifo C.,
RA Currier R.B., Salgado D., Pla D., Sanz L., Hyder A.S., Ribeiro J.M.,
RA Arntzen J.W., van den Thillart G.E., Boetzer M., Pirovano W., Dirks R.P.,
RA Spaink H.P., Duboule D., McGlinn E., Kini R.M., Richardson M.K.;
RT "The king cobra genome reveals dynamic gene evolution and adaptation in the
RT snake venom system.";
RL Proc. Natl. Acad. Sci. U.S.A. 110:20651-20656(2013).
CC -!- SUBCELLULAR LOCATION: Endomembrane system
CC {ECO:0000256|ARBA:ARBA00004184}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004184}.
CC -!- SIMILARITY: Belongs to the BORG/CEP family.
CC {ECO:0000256|ARBA:ARBA00010770}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ETE63252.1}.
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DR EMBL; AZIM01002840; ETE63252.1; -; Genomic_DNA.
DR AlphaFoldDB; V8NNY8; -.
DR Proteomes; UP000018936; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR GO; GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.
DR InterPro; IPR029273; Cdc42_effect-like.
DR InterPro; IPR000095; CRIB_dom.
DR PANTHER; PTHR15344:SF3; CDC42 EFFECTOR PROTEIN 3; 1.
DR PANTHER; PTHR15344; CDC42 EFFECTOR PROTEIN BORG; 1.
DR Pfam; PF14957; BORG_CEP; 1.
DR Pfam; PF00786; PBD; 1.
DR SMART; SM00285; PBD; 1.
DR PROSITE; PS50108; CRIB; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000018936}.
FT DOMAIN 31..45
FT /note="CRIB"
FT /evidence="ECO:0000259|PROSITE:PS50108"
FT REGION 207..229
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 207..222
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ETE63252.1"
SQ SEQUENCE 256 AA; 28542 MW; 690A50753C6B99C1 CRC64;
MPAKTPIYLK ADNNKKGKKF KLRDILSPDM ISPPLGDFRH TIHIGKEGQH DVFGDISFLK
GNYELLPGNE GETAASQYEG CNEFLRANST SDSVFIETPS PVLKNAISLP AIGGSQALML
PLLSPVTFNS KRDSLGPLRN PRHSCEPVME EKLQEKSKHL ENGKIYKDDI TWKQRAPASY
YTNGTDSHST SHSEQYTKWQ TEEFLDNPHL SCDQTKMQPQ SDDPLSDLAE PLLSLQLDLG
PSLLDEVLSV MDKNKS
//
