ID V8P2F9_OPHHA Unreviewed; 671 AA.
AC V8P2F9;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 24-JAN-2024, entry version 36.
DE SubName: Full=Cartilage acidic protein 1 {ECO:0000313|EMBL:ETE68002.1};
DE Flags: Fragment;
GN Name=CRTAC1 {ECO:0000313|EMBL:ETE68002.1};
GN ORFNames=L345_06201 {ECO:0000313|EMBL:ETE68002.1};
OS Ophiophagus hannah (King cobra) (Naja hannah).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera;
OC Serpentes; Colubroidea; Elapidae; Elapinae; Ophiophagus.
OX NCBI_TaxID=8665 {ECO:0000313|EMBL:ETE68002.1, ECO:0000313|Proteomes:UP000018936};
RN [1] {ECO:0000313|EMBL:ETE68002.1, ECO:0000313|Proteomes:UP000018936}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Blood {ECO:0000313|EMBL:ETE68002.1};
RX PubMed=24297900; DOI=10.1073/pnas.1314702110;
RA Vonk F.J., Casewell N.R., Henkel C.V., Heimberg A.M., Jansen H.J.,
RA McCleary R.J., Kerkkamp H.M., Vos R.A., Guerreiro I., Calvete J.J.,
RA Wuster W., Woods A.E., Logan J.M., Harrison R.A., Castoe T.A.,
RA de Koning A.P., Pollock D.D., Yandell M., Calderon D., Renjifo C.,
RA Currier R.B., Salgado D., Pla D., Sanz L., Hyder A.S., Ribeiro J.M.,
RA Arntzen J.W., van den Thillart G.E., Boetzer M., Pirovano W., Dirks R.P.,
RA Spaink H.P., Duboule D., McGlinn E., Kini R.M., Richardson M.K.;
RT "The king cobra genome reveals dynamic gene evolution and adaptation in the
RT snake venom system.";
RL Proc. Natl. Acad. Sci. U.S.A. 110:20651-20656(2013).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ETE68002.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AZIM01001124; ETE68002.1; -; Genomic_DNA.
DR AlphaFoldDB; V8P2F9; -.
DR Proteomes; UP000018936; Unassembled WGS sequence.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR CDD; cd00054; EGF_CA; 1.
DR Gene3D; 2.10.25.10; Laminin; 1.
DR InterPro; IPR027039; Crtac1.
DR InterPro; IPR001881; EGF-like_Ca-bd_dom.
DR InterPro; IPR018097; EGF_Ca-bd_CS.
DR InterPro; IPR013517; FG-GAP.
DR InterPro; IPR009030; Growth_fac_rcpt_cys_sf.
DR InterPro; IPR028994; Integrin_alpha_N.
DR PANTHER; PTHR16026; CARTILAGE ACIDIC PROTEIN 1; 1.
DR PANTHER; PTHR16026:SF0; CARTILAGE ACIDIC PROTEIN 1; 1.
DR Pfam; PF07645; EGF_CA; 1.
DR Pfam; PF13517; FG-GAP_3; 1.
DR SMART; SM00179; EGF_CA; 1.
DR SUPFAM; SSF57184; Growth factor receptor domain; 1.
DR SUPFAM; SSF69318; Integrin alpha N-terminal domain; 1.
DR PROSITE; PS01187; EGF_CA; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW EGF-like domain {ECO:0000256|ARBA:ARBA00022536};
KW Reference proteome {ECO:0000313|Proteomes:UP000018936};
KW Signal {ECO:0000256|ARBA:ARBA00022729}.
FT DOMAIN 597..644
FT /note="EGF-like calcium-binding"
FT /evidence="ECO:0000259|SMART:SM00179"
FT REGION 1..30
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ETE68002.1"
SQ SEQUENCE 671 AA; 73486 MW; 81D65D2D708E2C1F CRC64;
IHIHARRDRK SGGRRADAAT TASAREQGSP LARPLRMFRG QLVGMELPRQ STCPVPRLLL
LLLWSLVLPW PGEGSQRSKP MFTAVTDQIL PPDYDSNPTQ LNYGVAVTDA DRDGDFEIIV
AGYNGPNLVL KYDKARDRLL NLAVDEHSSP YYALRDRQGN AIGVTACDID GDGWEEIYFL
NTNNAFSGVA TYTDKLFKFR NGRWEDILSD EVNRGVASRF AGRSVACVDR LGSGRYSIYI
ANYANGRVGP HALIEMDTAA SDLEHGIVAL NDVAAEAGVN KFTGGRGIAV GPILSEAASD
IFCDNENGAN FLFQNQGDGT FIDVAPSTGL DDPYQHGRGV ALADFNRDGK VDLIYGNWNG
PHRLYLQVNA GGRIRFRDIA TPKLSMPSPV RTVIAADFDN DQELEVFFNN IAYRGSSANR
LFRVIRREHA DPAIEELNPG DAVEPEGRGT GGVVVDFDGD GKLDLILSHG ESMAQPLSVF
KVNEGAGNNW LRVIPRTRFG AFARGAKVVL FTRHSGAHLR IIDGGSGYLC EMEPDEPSSL
EVTWPDGKFI SRAVVSTEIN SVLEILYPKE TPGSPTILVP LECGQGFSQH KNGRCVDMDE
CAEFPFVCPR GRPICINTYG GYRCRSNKRC NRGFEPNEDG TACQCKTGSK YLNILGATLE
DFLLTHLCLL P
//
