ID V8P829_OPHHA Unreviewed; 817 AA.
AC V8P829;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE RecName: Full=Small ribosomal subunit protein eS19 {ECO:0000256|ARBA:ARBA00035143};
DE AltName: Full=40S ribosomal protein S19 {ECO:0000256|ARBA:ARBA00035466};
DE Flags: Fragment;
GN Name=Plxna1 {ECO:0000313|EMBL:ETE70480.1};
GN ORFNames=L345_03708 {ECO:0000313|EMBL:ETE70480.1};
OS Ophiophagus hannah (King cobra) (Naja hannah).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera;
OC Serpentes; Colubroidea; Elapidae; Elapinae; Ophiophagus.
OX NCBI_TaxID=8665 {ECO:0000313|EMBL:ETE70480.1, ECO:0000313|Proteomes:UP000018936};
RN [1] {ECO:0000313|EMBL:ETE70480.1, ECO:0000313|Proteomes:UP000018936}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Blood {ECO:0000313|EMBL:ETE70480.1};
RX PubMed=24297900; DOI=10.1073/pnas.1314702110;
RA Vonk F.J., Casewell N.R., Henkel C.V., Heimberg A.M., Jansen H.J.,
RA McCleary R.J., Kerkkamp H.M., Vos R.A., Guerreiro I., Calvete J.J.,
RA Wuster W., Woods A.E., Logan J.M., Harrison R.A., Castoe T.A.,
RA de Koning A.P., Pollock D.D., Yandell M., Calderon D., Renjifo C.,
RA Currier R.B., Salgado D., Pla D., Sanz L., Hyder A.S., Ribeiro J.M.,
RA Arntzen J.W., van den Thillart G.E., Boetzer M., Pirovano W., Dirks R.P.,
RA Spaink H.P., Duboule D., McGlinn E., Kini R.M., Richardson M.K.;
RT "The king cobra genome reveals dynamic gene evolution and adaptation in the
RT snake venom system.";
RL Proc. Natl. Acad. Sci. U.S.A. 110:20651-20656(2013).
CC -!- SIMILARITY: Belongs to the eukaryotic ribosomal protein eS19 family.
CC {ECO:0000256|ARBA:ARBA00010014}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ETE70480.1}.
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DR EMBL; AZIM01000545; ETE70480.1; -; Genomic_DNA.
DR AlphaFoldDB; V8P829; -.
DR Proteomes; UP000018936; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:1990904; C:ribonucleoprotein complex; IEA:UniProtKB-KW.
DR GO; GO:0005840; C:ribosome; IEA:UniProtKB-KW.
DR GO; GO:0017154; F:semaphorin receptor activity; IEA:InterPro.
DR GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR GO; GO:0006412; P:translation; IEA:InterPro.
DR CDD; cd01180; IPT_plexin_repeat1; 1.
DR CDD; cd01181; IPT_plexin_repeat3; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 3.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR014756; Ig_E-set.
DR InterPro; IPR002909; IPT_dom.
DR InterPro; IPR031148; Plexin.
DR InterPro; IPR013548; Plexin_cytoplasmic_RasGAP_dom.
DR InterPro; IPR046800; Plexin_RBD.
DR InterPro; IPR002165; Plexin_repeat.
DR InterPro; IPR016201; PSI.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR InterPro; IPR001266; Ribosomal_eS19.
DR InterPro; IPR018277; Ribosomal_eS19_CS.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR22625; PLEXIN; 1.
DR PANTHER; PTHR22625:SF35; PLEXIN-A1; 1.
DR Pfam; PF08337; Plexin_cytopl; 1.
DR Pfam; PF20170; Plexin_RBD; 1.
DR Pfam; PF01437; PSI; 1.
DR Pfam; PF01090; Ribosomal_S19e; 1.
DR Pfam; PF01833; TIG; 2.
DR SMART; SM00429; IPT; 2.
DR SMART; SM00423; PSI; 1.
DR SMART; SM01413; Ribosomal_S19e; 1.
DR SUPFAM; SSF81296; E set domains; 3.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR SUPFAM; SSF103575; Plexin repeat; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS00628; RIBOSOMAL_S19E; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000018936};
KW Ribonucleoprotein {ECO:0000256|ARBA:ARBA00023274};
KW Ribosomal protein {ECO:0000256|ARBA:ARBA00022980};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 497..521
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 105..158
FT /note="PSI"
FT /evidence="ECO:0000259|SMART:SM00423"
FT DOMAIN 159..255
FT /note="IPT/TIG"
FT /evidence="ECO:0000259|SMART:SM00429"
FT DOMAIN 317..417
FT /note="IPT/TIG"
FT /evidence="ECO:0000259|SMART:SM00429"
FT COILED 518..552
FT /evidence="ECO:0000256|SAM:Coils"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ETE70480.1"
SQ SEQUENCE 817 AA; 91342 MW; 168A039D4D655E44 CRC64;
MAPYDENWFY TRAASTTRHL YLQGGAVVSS MTKIYWGHQR NGVMPSHFSQ GSKIVARRVL
QALERLKIYF YEGNDISDLP VNLSVVWNGN FIIDNPQNIQ AHLYKCSALR ESCGLCLKAD
PRFECGWCVS EKRCSLRQHC PLSESSWMHA SNGNSRCADP KILKLFPETG PRQGGTRLTI
IGENLGLKFE DVRMGVRVGK VMCIPIESEY ISAEQIVCEI GEASPSKIQD APVEVCVRDC
SPSYKAIAPK SFTFVAPTFS QVIPSRGPLS GGTWISIRGR HLNAGSNITI PGSSAILIHI
NRAVLSSADV TYYYTEDPTI QKIEPEWSIR SGGTLLTVTG TNLATIKAPR IRAKYGTAEK
ENNCTVYNDT IMVCYAPSID NPVKSPSELG DRPDEIGFIM DNVQALLIIN RTNFIYYPDP
VIIYSASFLQ VLETNVLLEH RSWSYYINTP CALTVSETQL LCESPNLTGQ HKVTIKAGGF
EFSPGTLLIY SDNLLTLPAI IGIGGGGGLL LLIIIIVLIA YKRKSRDADR TLKRLQLQMD
NLESRVALEC KEAFAELQTD IHELTNDLDG AGIPFLDYCT YAMRVLFPGI EDHPVLKEME
VQANVEKSLT LFGQLLNKKH FLLTFIRTLE AQRSFSMRDR GNVASLIMTA LQGEMEYATG
VLKQLLSDLI EKNLESKNHP KLLLRRTESV AEKMLTNWFT FLLYKFLKEC AGEPLFMLYC
AIKQQMEKGP IDAITGEARY SLSEDKLIRQ QIDYKMLTLN CVNPENENAP EIPVKVLNCD
TITQVKEKLL DAVYKGVPYS QRPKAGDMDL GEQLLLV
//
