ID V8PEH5_OPHHA Unreviewed; 511 AA.
AC V8PEH5;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE SubName: Full=FAST kinase domain-containing protein 2 {ECO:0000313|EMBL:ETE72755.1};
DE Flags: Fragment;
GN Name=Fastkd2 {ECO:0000313|EMBL:ETE72755.1};
GN ORFNames=L345_01404 {ECO:0000313|EMBL:ETE72755.1};
OS Ophiophagus hannah (King cobra) (Naja hannah).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera;
OC Serpentes; Colubroidea; Elapidae; Elapinae; Ophiophagus.
OX NCBI_TaxID=8665 {ECO:0000313|EMBL:ETE72755.1, ECO:0000313|Proteomes:UP000018936};
RN [1] {ECO:0000313|EMBL:ETE72755.1, ECO:0000313|Proteomes:UP000018936}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Blood {ECO:0000313|EMBL:ETE72755.1};
RX PubMed=24297900; DOI=10.1073/pnas.1314702110;
RA Vonk F.J., Casewell N.R., Henkel C.V., Heimberg A.M., Jansen H.J.,
RA McCleary R.J., Kerkkamp H.M., Vos R.A., Guerreiro I., Calvete J.J.,
RA Wuster W., Woods A.E., Logan J.M., Harrison R.A., Castoe T.A.,
RA de Koning A.P., Pollock D.D., Yandell M., Calderon D., Renjifo C.,
RA Currier R.B., Salgado D., Pla D., Sanz L., Hyder A.S., Ribeiro J.M.,
RA Arntzen J.W., van den Thillart G.E., Boetzer M., Pirovano W., Dirks R.P.,
RA Spaink H.P., Duboule D., McGlinn E., Kini R.M., Richardson M.K.;
RT "The king cobra genome reveals dynamic gene evolution and adaptation in the
RT snake venom system.";
RL Proc. Natl. Acad. Sci. U.S.A. 110:20651-20656(2013).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ETE72755.1}.
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DR EMBL; AZIM01000181; ETE72755.1; -; Genomic_DNA.
DR AlphaFoldDB; V8PEH5; -.
DR Proteomes; UP000018936; Unassembled WGS sequence.
DR GO; GO:0005739; C:mitochondrion; IEA:UniProtKB-KW.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR GO; GO:0044528; P:regulation of mitochondrial mRNA stability; IEA:InterPro.
DR InterPro; IPR013579; FAST_2.
DR InterPro; IPR010622; FAST_Leu-rich.
DR InterPro; IPR013584; RAP.
DR PANTHER; PTHR21228:SF1; FAST KINASE DOMAIN-CONTAINING PROTEIN 2, MITOCHONDRIAL; 1.
DR PANTHER; PTHR21228; FAST LEU-RICH DOMAIN-CONTAINING; 1.
DR Pfam; PF06743; FAST_1; 1.
DR Pfam; PF08368; FAST_2; 1.
DR Pfam; PF08373; RAP; 1.
DR SMART; SM00952; RAP; 1.
DR PROSITE; PS51286; RAP; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:ETE72755.1};
KW Mitochondrion {ECO:0000256|ARBA:ARBA00023128};
KW Reference proteome {ECO:0000313|Proteomes:UP000018936};
KW Transferase {ECO:0000313|EMBL:ETE72755.1}.
FT DOMAIN 446..509
FT /note="RAP"
FT /evidence="ECO:0000259|PROSITE:PS51286"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ETE72755.1"
SQ SEQUENCE 511 AA; 58579 MW; 0725B10F896F891C CRC64;
MWMLKKNTLK NQKYDETKMM LEHPQFRQLC QYMMDNAKYI DSNDLAHTLL SVVKLGVPQN
TLLVQTLLRT CQERVNEFND RCVSIIANTL KVMEKCKNVE ALQLGLQLLL QDKVHKISNV
FVLQTIMRSI GKDVPLPLKK NLENKMLNLM GHFTVPNAFQ MFRVLGEMDY LSVPILNSCS
KTIIENIEGT QFSNLLNVLK TGKQLRYQNR TLYSALADYA ASVFYTWNRN EIILLLSAFE
NLSVHPVQLM DKFLEEVMLH PESLNLKDVI IILRAYSNLN HLSSTQNQEF LDSLNSILNK
HLHEIDNMDL LRVVYSFCLA GYLPQLALNQ LLQEEIINDL VKSGNSLSML SAINVCLELD
GNSSTTSTIL PEKLSSLPKK ILDFSYPEIQ EALLTLLENE NLFQTNVQLT QGYCLDFEIL
MDTNRKIALT STEADQLKGD PNLKRIAVLC PPASAFSNPS RHPKGRLAMK IRHLNRLGYQ
VILVSYKEFQ KLEKDEAVLF FKRQIFLAEN I
//
