ID V8PEW1_OPHHA Unreviewed; 432 AA.
AC V8PEW1;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 24-JAN-2024, entry version 40.
DE SubName: Full=TNF receptor-associated factor 5 {ECO:0000313|EMBL:ETE73094.1};
DE Flags: Fragment;
GN Name=TRAF5 {ECO:0000313|EMBL:ETE73094.1};
GN ORFNames=L345_01066 {ECO:0000313|EMBL:ETE73094.1};
OS Ophiophagus hannah (King cobra) (Naja hannah).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera;
OC Serpentes; Colubroidea; Elapidae; Elapinae; Ophiophagus.
OX NCBI_TaxID=8665 {ECO:0000313|EMBL:ETE73094.1, ECO:0000313|Proteomes:UP000018936};
RN [1] {ECO:0000313|EMBL:ETE73094.1, ECO:0000313|Proteomes:UP000018936}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Blood {ECO:0000313|EMBL:ETE73094.1};
RX PubMed=24297900; DOI=10.1073/pnas.1314702110;
RA Vonk F.J., Casewell N.R., Henkel C.V., Heimberg A.M., Jansen H.J.,
RA McCleary R.J., Kerkkamp H.M., Vos R.A., Guerreiro I., Calvete J.J.,
RA Wuster W., Woods A.E., Logan J.M., Harrison R.A., Castoe T.A.,
RA de Koning A.P., Pollock D.D., Yandell M., Calderon D., Renjifo C.,
RA Currier R.B., Salgado D., Pla D., Sanz L., Hyder A.S., Ribeiro J.M.,
RA Arntzen J.W., van den Thillart G.E., Boetzer M., Pirovano W., Dirks R.P.,
RA Spaink H.P., Duboule D., McGlinn E., Kini R.M., Richardson M.K.;
RT "The king cobra genome reveals dynamic gene evolution and adaptation in the
RT snake venom system.";
RL Proc. Natl. Acad. Sci. U.S.A. 110:20651-20656(2013).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ETE73094.1}.
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DR EMBL; AZIM01000140; ETE73094.1; -; Genomic_DNA.
DR AlphaFoldDB; V8PEW1; -.
DR Proteomes; UP000018936; Unassembled WGS sequence.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 2.
DR InterPro; IPR049440; TRAF3/5_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR017907; Znf_RING_CS.
DR InterPro; IPR001293; Znf_TRAF.
DR PANTHER; PTHR35760; SI:CH211-22I13.2; 1.
DR PANTHER; PTHR35760:SF1; SI:CH211-22I13.2; 1.
DR Pfam; PF21363; TRAF3_RING; 1.
DR Pfam; PF02176; zf-TRAF; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR SUPFAM; SSF49599; TRAF domain-like; 1.
DR PROSITE; PS00518; ZF_RING_1; 1.
DR PROSITE; PS50145; ZF_TRAF; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723, ECO:0000256|PROSITE-
KW ProRule:PRU00207}; Receptor {ECO:0000313|EMBL:ETE73094.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000018936};
KW Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|PROSITE-ProRule:PRU00207};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00207}.
FT DOMAIN 116..169
FT /note="TRAF-type"
FT /evidence="ECO:0000259|PROSITE:PS50145"
FT ZN_FING 116..169
FT /note="TRAF-type"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00207"
FT REGION 275..398
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 213..263
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 275..292
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 305..340
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 344..375
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 376..396
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ETE73094.1"
SQ SEQUENCE 432 AA; 50887 MW; 68FB96708799A49E CRC64;
MREAPLRDAP QLKPMASEDL AGQLPNLYIR QNSSNAVSLE FDPNVNYQFV EFLDERYKCT
RCHLVLHNPH QTGCGHRFCQ HCIVSFRYEW LHFLTIFVQI NATLQCIILL FCLQDHLQQC
LFETVQCTNE GCHEKMVLKD LKEHLIQQCN FRKEQCQYCK QPVISINLKT HEKVDCLNYP
WICPYGCMQM ILMKEIKRSK LLEHEDIFLK EHMLQIVDKN TKLEDQVKQL VQKENQQQCK
LDLRTLLDTI DNLKQKVALL ESYDQRLDMD NHHEAKDEIR CATSQEKTKV REESKRKRKR
SRSRSSSISS STSSSSSTSS SSRSSSRSSA SQSRSSSSSR DSSKVKAKKR KKEKHNKKKR
KKEKMKRKKE KKRKKEKSSP VQLSKYLKDK KKNHNYSMIT GKKIKMKIKK SKKDKERDRN
RAELLDFLNS TF
//
