ID V9DZV6_PHYPR Unreviewed; 740 AA.
AC V9DZV6;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 22-FEB-2023, entry version 23.
DE RecName: Full=Trehalase {ECO:0000256|RuleBase:RU361180};
DE EC=3.2.1.28 {ECO:0000256|RuleBase:RU361180};
DE AltName: Full=Alpha-trehalose glucohydrolase {ECO:0000256|RuleBase:RU361180};
GN ORFNames=F443_21243 {ECO:0000313|EMBL:ETI31838.1};
OS Phytophthora parasitica P1569.
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Phytophthora.
OX NCBI_TaxID=1317065 {ECO:0000313|EMBL:ETI31838.1, ECO:0000313|Proteomes:UP000018721};
RN [1] {ECO:0000313|EMBL:ETI31838.1, ECO:0000313|Proteomes:UP000018721}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=P1569 {ECO:0000313|EMBL:ETI31838.1,
RC ECO:0000313|Proteomes:UP000018721};
RG The Broad Institute Genomics Platform;
RA Russ C., Tyler B., Panabieres F., Shan W., Tripathy S., Grunwald N.,
RA Machado M., Johnson C.S., Arredondo F., Hong C., Coffey M., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Abouelleil A., Alvarado L.,
RA Chapman S.B., Gainer-Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M.,
RA Howarth C., Imamovic A., Ireland A., Larimer J., McCowan C., Murphy C.,
RA Pearson M., Poon T.W., Priest M., Roberts A., Saif S., Shea T., Sykes S.,
RA Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Phytophthora parasitica P1569.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=alpha,alpha-trehalose + H2O = alpha-D-glucose + beta-D-
CC glucose; Xref=Rhea:RHEA:32675, ChEBI:CHEBI:15377, ChEBI:CHEBI:15903,
CC ChEBI:CHEBI:16551, ChEBI:CHEBI:17925; EC=3.2.1.28;
CC Evidence={ECO:0000256|ARBA:ARBA00001576,
CC ECO:0000256|RuleBase:RU361180};
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 37 family.
CC {ECO:0000256|ARBA:ARBA00005615, ECO:0000256|RuleBase:RU361180}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ETI31838.1}.
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DR EMBL; ANIZ01003725; ETI31838.1; -; Genomic_DNA.
DR AlphaFoldDB; V9DZV6; -.
DR EnsemblProtists; ETI31838; ETI31838; F443_21243.
DR eggNOG; KOG0602; Eukaryota.
DR HOGENOM; CLU_006451_4_2_1; -.
DR OrthoDB; 1329212at2759; -.
DR Proteomes; UP000018721; Unassembled WGS sequence.
DR GO; GO:0004555; F:alpha,alpha-trehalase activity; IEA:UniProtKB-EC.
DR GO; GO:0005991; P:trehalose metabolic process; IEA:InterPro.
DR Gene3D; 1.50.10.10; -; 1.
DR InterPro; IPR008928; 6-hairpin_glycosidase_sf.
DR InterPro; IPR012341; 6hp_glycosidase-like_sf.
DR InterPro; IPR001661; Glyco_hydro_37.
DR InterPro; IPR018232; Glyco_hydro_37_CS.
DR PANTHER; PTHR23403; TREHALASE; 1.
DR PANTHER; PTHR23403:SF1; TREHALASE; 1.
DR Pfam; PF01204; Trehalase; 1.
DR PRINTS; PR00744; GLHYDRLASE37.
DR SUPFAM; SSF48208; Six-hairpin glycosidases; 1.
DR PROSITE; PS00927; TREHALASE_1; 1.
DR PROSITE; PS00928; TREHALASE_2; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295, ECO:0000256|RuleBase:RU361180};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU361180};
KW Reference proteome {ECO:0000313|Proteomes:UP000018721}.
SQ SEQUENCE 740 AA; 83991 MW; 6CCB089C5B7636FF CRC64;
MSPSSSSFAP SYSCMIEGSG RDEVEALKRT ALLDDKLNHD AASNEEKTLL LPKDQHQDDR
STLKRRDAAG VLGREVILRY VRWAMEILVV MIIVAGSLRL LSTKTCDHEV RRTPSFSLHR
SGGKLMHGGH RLRSFLRHMK SHPPVLGELP SDADITLGVD VELERAMDIY CHGPLLHAVQ
MANVFSDSKY FVDMPIKENS SAFDILVDFQ RRELAMTDYR PHAHDTHEQL LRRFINDHFD
PPGTDLLPIT PFDYQGQYHP PMVSDIQDNE LRDWAFGLHQ IWQTLGRIRN PNVKGSLLRS
RKLDAPSLNQ PANVLIVPGG RFRESYYWDS YWIVQGLLVS DMPITARGIV NHLLEYVSDY
GFVPNGGRIY YLTRSQPPML SDMVKLVARL PADGNESEYD EEYLRAALPI LEREYDFWMQ
HGPCGHAVEL TRRNSSAGAT DKATYVLNRY TSNANRPRPE SYREDVLVAA EIFDRTMQMD
GNAAATERHK DKYYNNVIAA AESGWDFSSR WLRDPLDMKS MVTSSVVPVD LNAIMYRVER
NLMEFNRHLG NDDRAQYFEG AAARRLEAID AILWSEKHKS WKDYDLETDT HSSIISVSDY
TPLWAKAFNS SDIDRLKHVV TSLKSSGLLQ VGGVQTTTIF SGQQWDSPNA WPPEQDIIVE
GLLAVNTTES YSLARELSQT WTQTSLTAWK QTGLMFEKYN SSEIGGLGAG GEYFPQFGFG
WTNGVILKFL TIHQNLLLAE
//
