ID V9E1W4_PHYPR Unreviewed; 1516 AA.
AC V9E1W4;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 24-JAN-2024, entry version 38.
DE SubName: Full=TKL protein kinase {ECO:0000313|EMBL:ETI32926.1};
GN ORFNames=F443_20353 {ECO:0000313|EMBL:ETI32926.1};
OS Phytophthora parasitica P1569.
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Phytophthora.
OX NCBI_TaxID=1317065 {ECO:0000313|EMBL:ETI32926.1, ECO:0000313|Proteomes:UP000018721};
RN [1] {ECO:0000313|EMBL:ETI32926.1, ECO:0000313|Proteomes:UP000018721}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=P1569 {ECO:0000313|EMBL:ETI32926.1,
RC ECO:0000313|Proteomes:UP000018721};
RG The Broad Institute Genomics Platform;
RA Russ C., Tyler B., Panabieres F., Shan W., Tripathy S., Grunwald N.,
RA Machado M., Johnson C.S., Arredondo F., Hong C., Coffey M., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Abouelleil A., Alvarado L.,
RA Chapman S.B., Gainer-Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M.,
RA Howarth C., Imamovic A., Ireland A., Larimer J., McCowan C., Murphy C.,
RA Pearson M., Poon T.W., Priest M., Roberts A., Saif S., Shea T., Sykes S.,
RA Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Phytophthora parasitica P1569.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ETI32926.1}.
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DR EMBL; ANIZ01003544; ETI32926.1; -; Genomic_DNA.
DR EnsemblProtists; ETI32926; ETI32926; F443_20353.
DR eggNOG; KOG0192; Eukaryota.
DR eggNOG; KOG0550; Eukaryota.
DR HOGENOM; CLU_251096_0_0_1; -.
DR OrthoDB; 69608at2759; -.
DR Proteomes; UP000018721; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0004672; F:protein kinase activity; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 3.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR001245; Ser-Thr/Tyr_kinase_cat_dom.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR44200; DNAJ HOMOLOG SUBFAMILY C MEMBER 7; 1.
DR PANTHER; PTHR44200:SF1; DNAJ HOMOLOG SUBFAMILY C MEMBER 7; 1.
DR Pfam; PF07714; PK_Tyr_Ser-Thr; 1.
DR Pfam; PF13432; TPR_16; 1.
DR Pfam; PF13181; TPR_8; 1.
DR SMART; SM00028; TPR; 9.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR SUPFAM; SSF48452; TPR-like; 3.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS50005; TPR; 4.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:ETI32926.1};
KW Lipoprotein {ECO:0000256|ARBA:ARBA00022707};
KW Myristate {ECO:0000256|ARBA:ARBA00022707};
KW Reference proteome {ECO:0000313|Proteomes:UP000018721};
KW TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339};
KW Transferase {ECO:0000313|EMBL:ETI32926.1}.
FT DOMAIN 265..583
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT REPEAT 1187..1220
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 1255..1288
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 1323..1356
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 1379..1412
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REGION 741..941
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 794..809
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 841..876
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 877..894
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 895..913
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1516 AA; 168280 MW; 8F12CD1EF15D6973 CRC64;
MDDDAMTSLL FEGQGRAISA ATSARSEAST APSSLNSMDQ AAMRTLPNAN KVLAFLHSIF
GLCQQVRDRP RACLQAHARL HQAFLRIASA AKHGSLPVSF RLSHFIVLLN QLKAVLDQHL
KLPNLVAKVA ASRRLLSGLA RVHHELNVVL VDNSLASATS SLLEWKQQFA SNRLQDEKTL
HDTLMALLST PTFVNKEFPS ERRQALVLLE LVAEFAANDP PRGHSSQLVE TLKMTHRRIS
NLCDLHLRRV PRWFLPGCEV DFSLTEHTIG HSRGSFGSTL HRGEAYRYNY NSEGALSSST
STVAVKCLWA LPDVQYQFVE QLFARSGVSK WTRVRHPNVV TVRGASHAAT PPFLVRDFTT
YSGLTSYLAA LETRAKQCAG PESSGKMETL TWQLLYGASR GLLHLHEQHS IVHGGLRCNN
ILVDKKGRAV IADFGLYTLA CDARDSGLTE YFQLDVFDAD AEELIRWQAP ECLREHVAYR
ESLRSLSETG SALVSSGSSA SATSFATDVY AFGMCILEAL TRTVPWAGLD IAKIRTLKGN
LSLLPSRPKY ISAQAWTLIE KMCAADPKQR ITLSEASQEL KRLGYGKRVF NRSRNSSSKD
LEGLETDAAS KVDRVSNVLE EVSQRLQHLS NESRSRGSST TDLKTMEAEA VAKVEHVSTS
LGEVSQELKE ISDRSRNGSS ADLVEIEEQA SQKLVCVSSL LNIASQELKR LGMGDKVSSE
SRSSSTQDLV AMAQEALAKL TRLSSEDSNR DEASVESRPD QSSNGDNEPV SPTDPLASPP
SVKTIEGVTA ATDLSAPSDA STVEQTGRRV KDSVSARRQR YSGAVAWDPA PVNEEGSGEN
WMSEEETKES VPRSREVVRS LHGALVEDHA DDQLTSTDDS AEASTAPESI SNRSTDDQPE
QEMDSDTGSF KDAISEEDSA VFLSDDDAEG VTTGESSTDD EALMIVPAEF QTARSYEEDD
DPTSPLHPVI SLLESLRTDE PDEARFVETL ATMKEDLELS TAWTIVEREG LLTLMELVWK
NYSDACTLCA LELLQSISGL SPDFVIVLVE SKLVKILLAV VKHRSSPQQV DFAASFLLEI
IAENDEAKRQ LWKCRGVGVM EDSLVLDRRL VQEVKSTMAK FKRSEGYKSL EDGEYHLAID
KFTEAIALDR KRAGYYGDRS LAYMEASMFK KAADDAYRCM RYNPYDVTGY LRHGLALKAL
GKYKEAIASL RKGTEVDPKF TKIHDALAEA ERLYKARLKG GDGTVLRRMT ASESAKLKKK
DGDDALRKKD FALAIECYSE ALELDPKNDW VYLHRSIAHA ARGDHPKAIE DASRCIRINY
RQVEGYYRLA LALHAAGQHD QALSTLYRGQ EVDPRHAGIT RFISQLEAEE AKAAGLPLTE
WFKEKGYRAF QLRSYEDAIK FYTKAIDASQ SDDDDVVMHC YLYRSRANQT RGEFTAVIAD
CTYVLERRPK NVFARLRRAD AYEQQRDFHM ALKDIRELVA LNPEYEDAHA RLRSLEHRCR
LLPGASEHKG VVEVDL
//
