ID V9F4R6_PHYPR Unreviewed; 829 AA.
AC V9F4R6;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE RecName: Full=DOMON domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=F443_10066 {ECO:0000313|EMBL:ETI45337.1};
OS Phytophthora parasitica P1569.
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Phytophthora.
OX NCBI_TaxID=1317065 {ECO:0000313|EMBL:ETI45337.1, ECO:0000313|Proteomes:UP000018721};
RN [1] {ECO:0000313|EMBL:ETI45337.1, ECO:0000313|Proteomes:UP000018721}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=P1569 {ECO:0000313|EMBL:ETI45337.1,
RC ECO:0000313|Proteomes:UP000018721};
RG The Broad Institute Genomics Platform;
RA Russ C., Tyler B., Panabieres F., Shan W., Tripathy S., Grunwald N.,
RA Machado M., Johnson C.S., Arredondo F., Hong C., Coffey M., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Abouelleil A., Alvarado L.,
RA Chapman S.B., Gainer-Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M.,
RA Howarth C., Imamovic A., Ireland A., Larimer J., McCowan C., Murphy C.,
RA Pearson M., Poon T.W., Priest M., Roberts A., Saif S., Shea T., Sykes S.,
RA Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Phytophthora parasitica P1569.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ETI45337.1}.
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DR EMBL; ANIZ01001710; ETI45337.1; -; Genomic_DNA.
DR AlphaFoldDB; V9F4R6; -.
DR EnsemblProtists; ETI45337; ETI45337; F443_10066.
DR eggNOG; KOG0039; Eukaryota.
DR HOGENOM; CLU_024610_0_0_1; -.
DR OrthoDB; 5489970at2759; -.
DR Proteomes; UP000018721; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR CDD; cd09631; DOMON_DOH; 1.
DR CDD; cd06186; NOX_Duox_like_FAD_NADP; 1.
DR Gene3D; 3.40.50.80; Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module; 1.
DR Gene3D; 2.40.30.10; Translation factors; 1.
DR InterPro; IPR045266; DOH_DOMON.
DR InterPro; IPR005018; DOMON_domain.
DR InterPro; IPR013112; FAD-bd_8.
DR InterPro; IPR017927; FAD-bd_FR_type.
DR InterPro; IPR013130; Fe3_Rdtase_TM_dom.
DR InterPro; IPR013121; Fe_red_NAD-bd_6.
DR InterPro; IPR039261; FNR_nucleotide-bd.
DR InterPro; IPR017938; Riboflavin_synthase-like_b-brl.
DR PANTHER; PTHR11972:SF210; DOMON DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR11972; NADPH OXIDASE; 1.
DR Pfam; PF08022; FAD_binding_8; 1.
DR Pfam; PF01794; Ferric_reduct; 1.
DR Pfam; PF08030; NAD_binding_6; 1.
DR SFLD; SFLDS00052; Ferric_Reductase_Domain; 1.
DR SFLD; SFLDG01168; Ferric_reductase_subgroup_(FRE; 1.
DR SUPFAM; SSF52343; Ferredoxin reductase-like, C-terminal NADP-linked domain; 1.
DR SUPFAM; SSF63380; Riboflavin synthase domain-like; 1.
DR PROSITE; PS50836; DOMON; 1.
DR PROSITE; PS51384; FAD_FR; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000018721};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 311..331
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 374..394
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 406..429
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 441..458
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 478..495
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 502..520
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 526..545
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 136..257
FT /note="DOMON"
FT /evidence="ECO:0000259|PROSITE:PS50836"
FT DOMAIN 502..655
FT /note="FAD-binding FR-type"
FT /evidence="ECO:0000259|PROSITE:PS51384"
SQ SEQUENCE 829 AA; 89141 MW; 79F147501512F6DF CRC64;
MVMQPHAPHT TGLIGCTTED YGRSRTPLNR RKQSRWSRIG FLLSVFTQFS FCSGSNRSNS
DSLSRVHPST RNFSYCSNCR IGRILRISVM ARSFLPLLAT ALAATSANMA SAAVSNSSIC
SSAAFQALSG TRLGDSPIFV RALVQGDEVC VEYQLEASVA SSATWFGVGP SRGSSMVSSP
AANVMMFFKD SGTPTSYVLG GYVNSDVTEE SDLSSFVVGS ASTTSMSFSF QRTLAAASSS
DVAISATGST DFIWAYGTSW PISTHRSGTN GVATFNVAAA ATATGSNAGA STTVSSSTST
PWCDDKNCPG IVGGVAFATM AVCGLLLTAA LKSSPVGKIL LHRTVAPPPV KMTTNAPVAK
PHTMFMQTLA DLHLGELLVM LIFVAAVIVL IALLSDEQNY VVSGQVSLLI LMFLILPVAR
LPVWSVLFGS SFERIVKFHR WLGLIMNVAV IVHVVQASDV VDLTLNEKYG EVTPLPGFVA
FICFIAMLFL SIEYIRRMFF EVFYFTHRVL SIVGFVFTIL HAPKFIGLAL CVPLGLYALG
LLYRWSSAFT GSYKASAIVH SGSNSTTLVL ESTPKTGKMA MNVNPGSYFL VRLPAISATQ
WHPFSSIVTP DGKSLGFTIK AMGNGSFTRK LLEKAGTQYD FTANLCGPFG KMSLNVDSYD
AVVLVAGGVG ITPMMSLINQ TRLFPTATGD SDKAPKASDW YVLWSVREPE DILMMEQFLP
THAQLDYAAR ASIQDPNMAI LGNNAPAPVN INWMFHVSNA RTDGVVTRAN GETLSYRGGQ
PILDELINTS RFNGRKVTVV ACGPPTMTVE AQALARNCNF DFHKEVFNW
//
